Transcriptome analysis of microglia in a mouse model of Rett syndrome: differential expression of genes associated with microglia/macrophage activation and cellular stress

Integrative transcriptome network analysis of iPSC-derived neurons from schizophrenia and schizoaffective disorder patients with 22q11.2 deletion

(2016) Mingyan Lin et al.   BMC Systems Biology

MECP2, a multi-talented modulator of chromatin architecture

(2016) Floriana Della Ragione et al.   Briefings in Functional Genomics

Enrichment of mutations in chromatin regulators in people with Rett syndrome lacking mutations in MECP2

(2016) Samin A. Sajan et al.   GENETICS IN MEDICINE

Whole exome sequencing of Rett syndrome-like patients reveals the mutational diversity of the clinical phenotype

(2016) Mario Lucariello et al.   HUMAN GENETICS

Crosstalk between astrocytic CXCL12 and microglial CXCR4 contributes to the development of neuropathic pain

(2016) Xin Luo et al.   Molecular Pain

Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology

(2016) P Dourlen et al.   MOLECULAR PSYCHIATRY

Schizophrenia risk from complex variation of complement component 4

(2016) Aswin Sekar et al.   NATURE

Merging data from genetic and epigenetic approaches to better understand autistic spectrum disorder

(2016) Dennis R Grayson et al.   Epigenomics

Manipulations of MeCP2 in glutamatergic neurons highlight their contributions to Rett and other neurological disorders

(2016) Xiangling Meng et al.   eLife

Restoration of Mecp2 expression in GABAergic neurons is sufficient to rescue multiple disease features in a mouse model of Rett syndrome

(2016) Kerstin Ure et al.   eLife

Microglia contribute to circuit defects in Mecp2 null mice independent of microglia-specific loss of Mecp2 expression

(2016) Dorothy P Schafer et al.   eLife

Neuron-Glia Interactions in Neural Plasticity: Contributions of Neural Extracellular Matrix and Perineuronal Nets

(2016) Egor Dzyubenko et al.   NEURAL PLASTICITY

MECP2 Duplication Syndrome: Evidence of Enhanced Oxidative Stress. A Comparison with Rett Syndrome

(2016) Cinzia Signorini et al.   PLoS One

De novoSHANK3mutation causes Rett syndrome-like phenotype in a female patient

(2015) Munetsugu Hara et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Exploring the possible link between MeCP2 and oxidative stress in Rett syndrome

(2015) Stefania Filosa et al.   FREE RADICAL BIOLOGY AND MEDICINE

Rett syndrome: disruption of epigenetic control of postnatal neurological functions

(2015) Amy E. Pohodich et al.   HUMAN MOLECULAR GENETICS

Methyl-CpG Binding Protein 2 Regulates Microglia and Macrophage Gene Expression in Response to Inflammatory Stimuli

(2015) James C. Cronk et al.   IMMUNITY

MECP2 disorders: from the clinic to mice and back

(2015) Laura Marie Lombardi et al.   JOURNAL OF CLINICAL INVESTIGATION

MECP2 missense mutations outside the canonical MBD and TRD domains in males with intellectual disability

(2015) Laura Bianciardi et al.   JOURNAL OF HUMAN GENETICS

Endothelial LSP1 Modulates Extravascular Neutrophil Chemotaxis by Regulating Nonhematopoietic Vascular PECAM-1 Expression

(2015) Mokarram Hossain et al.   JOURNAL OF IMMUNOLOGY

Dysregulation of Glutamine Transporter SNAT1 in Rett Syndrome Microglia: A Mechanism for Mitochondrial Dysfunction and Neurotoxicity

(2015) L.-W. Jin et al.   JOURNAL OF NEUROSCIENCE

Temporal profile of M1 and M2 responses in the hippocampus following early 24h of neurotrauma

(2015) Mubeen A. Ansari   JOURNAL OF THE NEUROLOGICAL SCIENCES

Altered neuronal network and rescue in a human MECP2 duplication model

(2015) S Nageshappa et al.   MOLECULAR PSYCHIATRY

Wild-type microglia do not reverse pathology in mouse models of Rett syndrome

(2015) Jieqi Wang et al.   NATURE

The role of inflammation and microglial activation in the pathophysiology of psychiatric disorders

(2015) G.Z. Réus et al.   NEUROSCIENCE

CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in neurodevelopment

(2015) Ping Wang et al.   Molecular Autism

Novel Markers to Delineate Murine M1 and M2 Macrophages

(2015) Kyle A. Jablonski et al.   PLoS One

Adult neuropsychiatric expression and familial segregation of 2q13 duplications

(2014) Gregory Costain et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Maternal immune activation leads to activated inflammatory macrophages in offspring

(2014) Charity E. Onore et al.   BRAIN BEHAVIOR AND IMMUNITY

Extracellular Hsp70: Export and Function

(2014) Antonio De Maio   CURRENT PROTEIN & PEPTIDE SCIENCE

MeCP2 Suppresses Nuclear MicroRNA Processing and Dendritic Growth by Regulating the DGCR8/Drosha Complex

(2014) Tian-Lin Cheng et al.   DEVELOPMENTAL CELL

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Interferon-Induced Ifit Proteins: Their Role in Viral Pathogenesis

(2014) Volker Fensterl et al.   JOURNAL OF VIROLOGY

De novo mutations in schizophrenia implicate chromatin remodeling and support a genetic overlap with autism and intellectual disability

(2014) S E McCarthy et al.   MOLECULAR PSYCHIATRY

The impact of microglial activation on blood-brain barrier in brain diseases

(2014) Anna Carolina Carvalho da Fonseca et al.   Frontiers in Cellular Neuroscience

Conditional deletion of Mecp2 in parvalbumin-expressing GABAergic cells results in the absence of critical period plasticity

(2014) Ling-jie He et al.   Nature Communications

Transcriptome analysis reveals dysregulation of innate immune response genes and neuronal activity-dependent genes in autism

(2014) Simone Gupta et al.   Nature Communications

Genome-Wide Association Meta-analysis of Neuropathologic Features of Alzheimer's Disease and Related Dementias

(2014) Gary W. Beecham et al.   PLoS Genetics

Translational Regulation of Specific mRNAs Controls Feedback Inhibition and Survival during Macrophage Activation

(2014) Johanna Schott et al.   PLoS Genetics

Recurrent duplications of the annexin A1 gene (ANXA1) in autism spectrum disorders

(2014) Catarina T Correia et al.   Molecular Autism

Exome sequencing of extended families with autism reveals genes shared across neurodevelopmental and neuropsychiatric disorders

(2014) Holly N Cukier et al.   Molecular Autism

Rare-Variant Extensions of the Transmission Disequilibrium Test: Application to Autism Exome Sequence Data

(2013) Zongxiao He et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Converging Pathways in Autism Spectrum Disorders: Interplay between Synaptic Dysfunction and Immune Responses

(2013) Irina Voineagu et al.   Frontiers in Human Neuroscience

Lipoprotein Lipase (LPL) is Associated with Neurite Pathology and Its Levels Are Markedly Reduced in the Dentate Gyrus of Alzheimer’s Disease Brains

(2013) Huilin Gong et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Oligodendrocyte Lineage Cells Contribute Unique Features to Rett Syndrome Neuropathology

(2013) M. V. C. Nguyen et al.   JOURNAL OF NEUROSCIENCE

Activated Cyclin-Dependent Kinase 5 Promotes Microglial Phagocytosis of Fibrillar β-Amyloid by Up-regulating Lipoprotein Lipase Expression

(2013) Yuanhui Ma et al.   MOLECULAR & CELLULAR PROTEOMICS

Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain

(2013) Junjie U Guo et al.   NATURE NEUROSCIENCE

Age-Related Behavioral Phenotype of an Astrocytic Monoamine Oxidase-B Transgenic Mouse Model of Parkinson’s Disease

(2013) Christopher A. Lieu et al.   PLoS One

Common Variants on Xq28 Conferring Risk of Schizophrenia in Han Chinese

(2013) Emily H.M. Wong et al.   SCHIZOPHRENIA BULLETIN

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

RSeQC: quality control of RNA-seq experiments

(2012) Liguo Wang et al.   BIOINFORMATICS

MeCP2 Binds to 5hmC Enriched within Active Genes and Accessible Chromatin in the Nervous System

(2012) Marian Mellén et al.   CELL

Microglia as modulators of cognition and neuropsychiatric disorders

(2012) Thomas Blank et al.   GLIA

Microglial Cell Activation is a Source of Metalloproteinase Generation during Hemorrhagic Transformation

(2012) Gregory J del Zoppo et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Wild-type microglia arrest pathology in a mouse model of Rett syndrome

(2012) Noël C. Derecki et al.   NATURE

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

The role of microglia in brain maintenance: implications for Rett syndrome

(2012) Noël C. Derecki et al.   TRENDS IN IMMUNOLOGY

The Complement Control-Related Genes CSMD1 and CSMD2 Associate to Schizophrenia

(2011) Bjarte Håvik et al.   BIOLOGICAL PSYCHIATRY

Transcriptomic analysis of autistic brain reveals convergent molecular pathology

(2011) Irina Voineagu et al.   NATURE

A role for glia in the progression of Rett’s syndrome

(2011) Daniel T. Lioy et al.   NATURE

Synaptic plasticity deficits in an experimental model of rett syndrome: long-term potentiation saturation and its pharmacological reversal

(2011) S.-M. Weng et al.   NEUROSCIENCE

Gene expression in blood is associated with risperidone response in children with autism spectrum disorders

(2011) L Lit et al.   PHARMACOGENOMICS JOURNAL

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

TheMECP2duplication syndrome

(2010) Melissa B. Ramocki et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Abnormalities of cell packing density and dendritic complexity in the MeCP2 A140V mouse model of Rett syndrome/X-linked mental retardation

(2010) Garilyn M Jentarra et al.   BMC NEUROSCIENCE

ToppGene Suite for gene list enrichment analysis and candidate gene prioritization

(2009) J. Chen et al.   NUCLEIC ACIDS RESEARCH

A novel hypomorphic MECP2 point mutation is associated with a neuropsychiatric phenotype

(2008) Abidemi A. Adegbola et al.   HUMAN GENETICS