Article
Biochemical Research Methods
Fuchun Si, Zenghui Liu, Jinge Li, Huaixia Yang, Yanju Liu, Jinming Kong
Summary: An electrochemical detection strategy for exosomes was established based on DNA/ferrocene-modified single-walled carbon nanotube complex. The method showed high sensitivity and good selectivity, providing a potential platform for early diagnosis and biomedical applications.
ANALYTICAL BIOCHEMISTRY
(2023)
Article
Chemistry, Analytical
Xiaoyan Gan, Feng Qiu, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: An electrochemical assay for ACP in human serum samples using DNA extension and magnetic bead technologies on rGO-modified electrode was developed, providing high sensitivity and selectivity with a wide detection range and low detection limit.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Chenhui Wu, Yunkang Ma, Lihua Chen
Summary: In this study, a low-cost, portable, and reusable biosensor was developed for the rapid and selective quantization of tuberculosis gene in early-stage serum samples. The biosensor exhibited antifouling properties and could be used for complex biological systems. The biosensor, based on DNA double strand reversible bonding, showed a fast response with good linear concentration dependence on the target DNA. Furthermore, the biosensor could be reused after regeneration, reducing the overall cost.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Physical
A. G. Kamaha Tchekep, V. Suryanarayanan, Deepak K. Pattanayak
Summary: A new approach combining silver nanoparticles (AgNPs) with multiwalled carbon nanotubes (MWCNTs) and graphene oxide (GO) was developed for highly sensitive and interference-free electroanalysis of dopamine (DA), which is crucial for the diagnosis and monitoring of neurodegenerative disorders.
Article
Chemistry, Multidisciplinary
Mohsin Amin, Badr M. M. Abdullah, Stephen R. R. Wylie, Samuel J. J. Rowley-Neale, Craig E. E. Banks, Kathryn A. A. Whitehead
Summary: This study developed a MWCNT-based enzymatic biosensor for the voltammetric detection of cadaverine. The biosensor exhibited high sensitivity and linear concentration dependence, and it was also effective when tested in artificial saliva.
Article
Biophysics
Lin Huang, Peipei Li, Chen Lin, Yongning Wu, Zhiqiang Chen, FengFu Fu
Summary: A novel aptamer for detecting organic mercury was designed, and a label-free fluorescent method for sensitive and specific determination of organic mercury total concentration was developed. The method showed rapid, accurate, and reliable characteristics, making it suitable for detecting organic mercury in environmental and biological samples.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Environmental Sciences
Yangyang Chen, Qian Zhu, Xiaohong Zhou, Ruoyu Wang, Zhenchuan Yang
Summary: The homemade waveguide-based evanescent wave aptasensor demonstrated high selectivity and stability for the online monitoring of mercury pollution in water samples, with a detection limit of 0.2 μg/L and a linear range from 1.4 to 240.7 μg/L. The sensor's negligible environmental matrix effect and cross reactivity towards other metal ions ensured its reliability for real-time monitoring and emergency treatment of pollution incidents.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Chemistry, Analytical
Chittatosh Pal, Subrata Majumder
Summary: The feasibility of designing a highly selective and sensitive label-free biosensor for the determination of Hg2+ ions using gold electrodes functionalized with DNA-wrapped carbon nanotubes was examined. The detection limit of 1 femtomolar was achieved, and the method showed good selectivity against common metal cations.
Article
Chemistry, Analytical
Kentaro Ito, Kumi Y. Inoue, Kosuke Ino, Hitoshi Shiku
Summary: A highly sensitive immunoassay for human immunoglobulin G (IgG) using signal amplification of the coagulation cascade is reported. The reaction product, pNA, was quantified using square wave voltammetry with a glassy carbon electrode. Thrombin efficiently reacted with the substrate FPK-pNA and factor XIa was not inactivated during labeling. The coagulation cascade-based immunoassay showed high selectivity and sensitivity for human IgG.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Jerson Gonzalez-Hernandez, Guillermo Moya-Alvarado, Ana Lorena Alvarado-Gamez, Roberto Urcuyo, Miriam Barquero-Quiros, Maria Julia Arcos-Martinez
Summary: Fentanyl, a synthetic opioid used for severe pain treatment, has become a growing threat to public health due to its increasing illegal recreational use. This study proposes a novel enzymatic biosensor for the rapid and reliable determination of fentanyl in urine samples, using adsorptive-stripping cyclic voltammetry. The biosensor showed high sensitivity, wide linearity range, and low detection limits, making it an efficient device for fentanyl detection.
Article
Biophysics
Yuan Cheng, Hongliang Wang, Yuxin Zhuo, Dan Song, Chunsheng Li, Anna Zhu, Feng Long
Summary: This paper presents an innovative reusable smartphone-facilitated mobile fluorescence biosensor that combines optical system, microfluidic system, and smartphone to achieve rapid detection and quantitative analysis of toxic pollutants.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Biochemistry & Molecular Biology
Yaping Zhang, Peipei Li, Mengyuan Hou, Luyao Chen, Jianfeng Wang, Huaixia Yang, Weisheng Feng
Summary: An electrochemical biosensor for detecting TMV RNA is constructed using ARGET ATRP and DSN-assisted target recycling. The method shows high sensitivity, superior selectivity, excellent stability, and good reproducibility. It demonstrates satisfactory applicability in detecting TMV RNA in real samples.
BIOELECTROCHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Nataliya Stasyuk, Olha Demkiv, Galina Gayda, Oksana Zakalska, Andriy Zakalskiy, Roman Serkiz, Taras Kavetskyy, Mykhailo Gonchar
Summary: In this study, a convenient method for ethanol assay using nanozymes as peroxidase mimetics was proposed. The results showed that this method has good accuracy and sensitivity, and can be used for quantitative analysis of ethanol in alcoholic beverages.
Article
Chemistry, Analytical
Lingling Wang, Xiaohui Lin, Ting Liu, Zhaohuan Zhang, Jie Kong, Hai Yu, Juan Yan, Donglei Luan, Yong Zhao, Xiaojun Bian
Summary: A reusable and universal impedimetric sensing platform based on a bacteria-imprinted polythiophene film (BIF) is proposed for the rapid and sensitive detection of pathogenic bacteria. The sensor exhibits excellent selectivity and can be applied in the analysis of real samples.
Article
Electrochemistry
Palraj Kalimuthu, Tobias Kruse, Paul V. Bernhardt
Summary: The electrochemical nitrate biosensor utilizes nitrate reductase from Neurospora crassa, entrapped within a polymeric chitosan matrix on a glassy carbon electrode, with the electron mediator anthraquinone sulfonate. The sensor shows high sensitivity, selectivity, and long-term stability, and is successfully applied for nitrate detection in lake and river water samples.
ELECTROCHIMICA ACTA
(2021)
Article
Engineering, Chemical
Sijian Zhang, Ying Xie, Jingyu Feng, Zhenyu Chu, Wanqin Jin
Summary: A screen-printed biosensing microchip (SPBM) was proposed for analyzing ethanol concentration during fermentation through a well-defined nanocubic structure, enabling direct detection of fermentation broth without pretreatment; the microchip exhibited high sensitivity and electrocatalysis, allowing accurate and rapid monitoring of ethanol concentration during fermentation.
Article
Engineering, Chemical
Tao Liu, Ying Xie, Lei Shi, Yu Liu, Zhenyu Chu, Wanqin Jin
Summary: Water pollution is increasingly serious, affecting human health. Electrochemical biosensors play an important role in pollution detection, but stability and sensitivity are challenging. A novel composite film structure was successfully developed to enhance sensitivity in biosensors.
CHINESE JOURNAL OF CHEMICAL ENGINEERING
(2021)
Article
Chemistry, Analytical
Nisha Zhuang, Jieyu Ma, Lu Yang, Rui Xue, Xiujuan Qian, Minjiao Chen, Sijian Zhang, Zhenyu Chu, Weiliang Dong, Jie Zhou, Min Jiang
Summary: An amperometric biosensor utilizing PB nanocubes microchip was developed for rapid and accurate determination of sucrose and glucose contents in fermentation broth and juice samples. The biosensor showed high performance and strong anti-interference, with fast response time, wide linear range, and good recovery rate, indicating its potential for applications in fermentation industry and beverage products.
MICROCHEMICAL JOURNAL
(2021)
Article
Engineering, Chemical
Min Lu, Mengxuan Liu, Chunli Xu, Yu Yin, Lei Shi, Hong Wu, Aihua Yuan, Xiao-Ming Ren, Shaobin Wang, Hongqi Sun
Summary: Refractory antibiotics in domestic wastewater are difficult to eliminate completely using conventional methods, leading to environmental contamination and negative impacts on public health. This study utilized advanced oxidation processes (AOPs) to remove sulfachloropyridazine (SCP) antibiotics. Nanosized Mn2O3 catalysts were synthesized on SBA-15 material to activate potassium peroxydisulfate (PDS) and generate reactive oxygen radicals for SCP degradation. The location and size of Mn2O3 were found to significantly influence the oxidation activity, with Mn2O3 at the interior of SBA-15 showing complete SCP removal. The study also revealed the importance of SO4???- species as decisive radicals in the SCP degradation processes. Exploring the use of as-made mesoporous silica as a support provides new insights for the development of environmentally friendly catalysts.
CHINESE JOURNAL OF CHEMICAL ENGINEERING
(2022)
Article
Engineering, Chemical
Lei Shi, Yu Yin, Hong Wu, Rajan Arjan Kalyan Hirani, Xinyuan Xu, Jinqiang Zhang, Nasir Rafique, Abdul Hannan Asif, Shu Zhang, Hongqi Sun
Summary: This study proposes a template-assisted strategy to construct a hollow Cr2O3 nanocatalyst with controllable morphology. The hollow structure enhances the efficiency of N-2 conversion to NH3 and exhibits outstanding electrocatalytic performance.
CHINESE JOURNAL OF CHEMICAL ENGINEERING
(2022)
Article
Engineering, Biomedical
Huajie Zou, Fuhai Cai, Jianghua Zhang, Zhenyu Chu
Summary: With the development of environmental energy harvesting technology, the research focus has shifted towards the energy harvesting system of coupled environmental vibration sources, particularly on the piezoelectric energy harvesting technology based on the piezoelectric effect. The study reviewed and summarized the different types of piezoelectric energy harvesting, highlighting the benefits of rotational types, the limitations of vortex-induced vibration and flutter types, and the effectiveness of resonant types in improving energy and power output. The future main development tendencies involve multiple frequency excitation and multi-piezoelectric array for enhanced power generation capacity and broader range of airflow velocity.
JOURNAL OF VIBROENGINEERING
(2022)
Article
Biophysics
Tao Liu, Bowen Lin, Xueli Yuan, Zhenyu Chu, Wanqin Jin
Summary: In this study, a novel electrochemical aptasensor was developed for ultrasensitive and quantitative detection of trace Hg2+. The aptasensor utilized an urchin-like architecture of Cu@carbon nanoneedles as the electroactive probe and employed an exonuclease III-assisted cycling amplification strategy to enhance the signal strength of trace Hg2+. The developed aptasensor exhibited a low detection limit and wide linear range, and it shows promising potential for early warning and efficient pollution monitoring of heavy metal ions.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Food Science & Technology
Ke Zhang, Hui Zeng, Jingyu Feng, Zhengkun Liu, Zhenyu Chu, Wanqin Jin
Summary: Allura red (AR) is commonly used as a food and soft drink additive, but due to the special harm of the azo structure to the human body, dosage control is necessary. To address the issues of time-consuming, expensive, and complicated detection methods, a core-shell nanocube sensor has been developed for ultrawide detection range and selective recognition of AR. This sensor exhibits excellent selectivity with an ultra-wide linear range and remarkable anti-interference and reusability over 30 days.
FOOD AND CHEMICAL TOXICOLOGY
(2022)
Article
Engineering, Multidisciplinary
Chengzhang Zhu, Haiqian Yao, Shukun Le, Yu Yin, Chuanxiang Chen, Haitao Xu, Shaobin Wang, Xiaoguang Duan
Summary: The fabrication of ultrathin TiO2(B) nanosheets-decorated hierarchical In2S3 spheres forming an efficient IT-1.5:1 heterojunction led to a superior photocatalytic degradation performance. The S-scheme structure at the In2S3/TiO2(B) interface provided an internal electron channel and maintained active sites, offering new insights for the design of sustainable water purification catalysts.
COMPOSITES PART B-ENGINEERING
(2022)
Article
Engineering, Environmental
Yu Yin, Mengxuan Liu, Lei Shi, Shu Zhang, Rajan Arjan Kalyan Hirani, Chengzhang Zhu, Chuanxiang Chen, Aihua Yuan, Xiaoguang Duan, Shaobin Wang, Hongqi Sun
Summary: Ru species loaded on 2D graphitic carbon nitride material exhibited excellent catalytic activity for organic compound removal. The dispersion degree of Ru was crucial to the catalytic performance, achieved by optimizing the preparation process and obtaining Ru-pCN catalysts with homogeneous dispersion of Ru species.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Nanoscience & Nanotechnology
Ke Zhang, Meiqi Wang, Tao Liu, Zhenyu Chu, Wanqin Jin
Summary: In this study, we developed an ultrasensitive biosensor microchip that can rapidly and accurately detect sucrose concentration by constructing a special microarchitecture. This research is of great importance for industrial fermentation and synthetic biology research.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Review
Engineering, Chemical
Xiaoyue Yao, Yu Liu, Zhenyu Chu, Wanqin Jin
Summary: Since the global outbreak of COVID-19, membrane technology has received significant attention for its crucial role in clinical treatments. Membranes are essential in various fields of life science and possess additional functions to meet specific clinical requirements. This review introduces and discusses advanced membranes and their functions in four typical areas of life science. A comparison of the advantages and disadvantages of these membranes is provided, along with guidance for selecting and fabricating the appropriate membrane material.
CHINESE JOURNAL OF CHEMICAL ENGINEERING
(2022)
Article
Environmental Sciences
Jing Zhang, Jing Lei, Zhengkun Liu, Zhenyu Chu, Wanqin Jin
Summary: With the rapid development of industrial society, phenolic pollutants in water pose serious threats to human health. Traditional detection techniques are not cost-effective and lack on-site detection abilities. Electrochemical enzymatic biosensors have gained increasing attention as an effective strategy for the recognition of phenolic compounds. However, challenges such as enzyme deactivation, poor stability, and low sensitivity need to be addressed. Effective immobilization methods of enzymes and nanomaterials with excellent properties are being extensively researched to achieve high-sensitivity and high-stability biosensing platforms. Simultaneous detection of multiple phenols is also an area of focus for future research.
ENVIRONMENTAL RESEARCH
(2022)
Review
Engineering, Biomedical
Xueli Yuan, Bowen Lin, Tao Liu, Wei Zhang, Zhenyu Chu, Xiaoping Gu, Zhengliang Ma, Wanqin Jin
Summary: Cancer is a malignant disease with a high fatality rate, and early screening with rapid and accurate detection is crucial for improving the survival rate. Electrochemical biosensors that detect cancer biomarkers in blood offer advantages such as low invasiveness, fast diagnosis, and low cost. However, there is a trade-off between sensitivity and selectivity, which limits the detection of trace amounts of biomarkers. Recently, nanomaterials with improved sensitivity and selectivity have been developed to address this issue. This review introduces different categories of state-of-the-art electrochemical biosensors, discusses their operating principles and advantages/disadvantages, and evaluates the existing detection strategies and performance of nanomaterial-based cancer biosensors.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Engineering, Electrical & Electronic
Shilin Yang, Cuimei Bo, Jun Li, Qiang Tan, Yiqing Wang, Hao Wu, Zhenyu Chu, Wanqin Jin
Summary: A homemade enzymatic biosensor chip and a specific signal conversion system were proposed for online glucose analysis. The system exhibited high sensitivity and a wide linear range, enabling accurate detection of glucose concentration during fermentation.
IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT
(2022)
Article
Materials Science, Biomaterials
Izabela Stupka, Artur P. Biela, Bernard Piette, Agnieszka Kowalczyk, Karolina Majsterkiewicz, Kinga Borzecka-Solarz, Antonina Naskalska, Jonathan G. Heddle
Summary: Artificial protein cages, such as TRAP-cages, have potential applications in vaccines and drug delivery. TRAP-cages have the ability to control the disassembly conditions by modifying the interface between their building blocks. By using TRAP rings with different numbers of monomers, it is possible to predict the formation of other cages.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
Article
Materials Science, Biomaterials
Guo Zhang, Yu Wang, Hua Qiu, Lei Lu
Summary: This study presents a one-pot synthesis method for flower-like AMPs@EAMP particles by combining antimicrobial peptides with ellagic acid, offering enlarged surface area, excellent biocompatibility, and broad-spectrum antibacterial activity. In vivo studies indicate their potential for tissue repair and immune barrier reconstruction.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
Article
Materials Science, Biomaterials
Jiamei Zhang, Lingshuang Wang, Cheng Xu, Yingui Cao, Shengsheng Liu, Rui L. Reis, Subhas C. Kundu, Xiao Yang, Bo Xiao, Lian Duan
Summary: Pluronic F127 modified silk fibroin film with different types of antibacterial agents could accelerate wound recovery by promoting fibroblast adhesion, eradicating bacteria, and facilitating angiogenesis and re-epithelialization.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
Article
Materials Science, Biomaterials
Yinsheng Liu, Mingyue Wang, Yinfei Hui, Lei Sun, Yanrui Hao, Henlong Ren, Hao Guo, Wu Yang
Summary: In this study, a rare-earth hybrid luminescent material was developed for the detection of a biomarker for anthrax. The material showed excellent selectivity and high sensitivity, allowing for the determination of the biomarker in saliva and urine. Additionally, a convenient point-of-care testing method using fluorescent test paper and a smartphone was established for the initial diagnosis of anthrax.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
Review
Materials Science, Biomaterials
Wenshuai Yang, Jingsi Chen, Ziqian Zhao, Meng Wu, Lu Gong, Yimei Sun, Charley Huang, Bin Yan, Hongbo Zeng
Summary: Injectable hydrogels with shear-thinning and/or in situ formation properties offer distinct advantages in bioengineering applications, as they can be directly delivered to target sites, possess self-healing abilities, and simplify the implantation process.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)