Immunofibrogenic Gene Expression Patterns in Tanzanian Children with Ocular Chlamydia trachomatis Infection, Active Trachoma and Scarring: Baseline Results of a 4-Year Longitudinal Study

Effects of MMP12 on cell motility and inflammation during corneal epithelial repair

(2017) Marie Wolf et al.   EXPERIMENTAL EYE RESEARCH

Chlamydia cell biology and pathogenesis

(2016) Cherilyn Elwell et al.   NATURE REVIEWS MICROBIOLOGY

Immunohistochemical Analysis of Scarring Trachoma Indicates Infiltration by Natural Killer and Undefined CD45 Negative Cells

(2016) Victor H. Hu et al.   PLoS Neglected Tropical Diseases

Blinding Trachoma: Systematic Review of Rates and Risk Factors for Progressive Disease

(2016) Athumani M. Ramadhani et al.   PLoS Neglected Tropical Diseases

The Relationship between Active Trachoma and Ocular Chlamydia trachomatis Infection before and after Mass Antibiotic Treatment

(2016) Athumani M. Ramadhani et al.   PLoS Neglected Tropical Diseases

Increased Epithelial Expression of CTGF and S100A7 with Elevated Subepithelial Expression of IL-1β in Trachomatous Trichiasis

(2016) Tamsyn Derrick et al.   PLoS Neglected Tropical Diseases

Intravaginal Chlamydia trachomatis Challenge Infection Elicits TH1 and TH17 Immune Responses in Mice That Promote Pathogen Clearance and Genital Tract Damage

(2016) Rodolfo D. Vicetti Miguel et al.   PLoS One

Fibroblasts profiling in scarring trachoma identifies IL-6 as a functional component of a fibroblast-macrophage pro-fibrotic and pro-inflammatory feedback loop

(2016) Jenny Z. Kechagia et al.   Scientific Reports

Inverse relationship between microRNA-155 and -184 expression with increasing conjunctival inflammation during ocular Chlamydia trachomatis infection

(2015) Tamsyn Derrick et al.   BMC INFECTIOUS DISEASES

Mucosal Barrier Depletion and Loss of Bacterial Diversity are Primary Abnormalities in Paediatric Ulcerative Colitis

(2015) Misagh Alipour et al.   Journal of Crohns & Colitis

Conjunctival fibrosis and the innate barriers to Chlamydia trachomatis intracellular infection: a genome wide association study

(2015) Chrissy h. Roberts et al.   Scientific Reports

Pathogenesis of Progressive Scarring Trachoma in Ethiopia and Tanzania and Its Implications for Disease Control: Two Cohort Studies

(2015) Matthew J. Burton et al.   PLoS Neglected Tropical Diseases

CD8+ T Cells Define an Unexpected Role in Live-Attenuated Vaccine Protective Immunity against Chlamydia trachomatis Infection in Macaques

(2014) N. Olivares-Zavaleta et al.   JOURNAL OF IMMUNOLOGY

Trachoma

(2014) Hugh R Taylor et al.   LANCET

Tumor Suppressor p53 Alters Host Cell Metabolism to Limit Chlamydia trachomatis Infection

(2014) Christine Siegl et al.   Cell Reports

The conjunctival microbiome in health and trachomatous disease: a case control study

(2014) Yanjiao Zhou et al.   Genome Medicine

The Effect of Multiple Rounds of Mass Drug Administration on the Association between Ocular Chlamydia trachomatis Infection and Follicular Trachoma in Preschool-Aged Children

(2014) Jennifer S. Lee et al.   PLoS Neglected Tropical Diseases

The Role of the Immune Response in Chlamydia trachomatis Infection of the Male Genital Tract: A Double-Edged Sword

(2014) Kate A. Redgrove et al.   Frontiers in Immunology

IL-23 Induces IL-22 and IL-17 Production in Response toChlamydia muridarumGenital Tract Infection, but the Absence of these Cytokines does not Influence Disease Pathogenesis

(2013) Lauren C. Frazer et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Chlamydia inhibit host cell apoptosis by inducing Bag-1 via the MAPK/ERK survival pathway

(2013) Du Kun et al.   APOPTOSIS

In vivo confocal microscopy and histopathology of the conjunctiva in trachomatous scarring and normal tissue: a systematic comparison

(2013) Victor H Hu et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

The dynamics of gut-associated microbial communities during inflammation

(2013) Sebastian E Winter et al.   EMBO REPORTS

Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis

(2013) Malin E V Johansson et al.   GUT

IL-22, not simply a Th17 cytokine

(2013) Sascha Rutz et al.   IMMUNOLOGICAL REVIEWS

Plasmid Copy Number and Disease Severity in Naturally Occurring Ocular Chlamydia trachomatis Infection

(2013) A. R. Last et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Development and Evaluation of a Next-Generation Digital PCR Diagnostic Assay for Ocular Chlamydia trachomatis Infections

(2013) C. h. Roberts et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Hevin Plays a Pivotal Role in Corneal Wound Healing

(2013) Shyam S. Chaurasia et al.   PLoS One

Conjunctival MicroRNA Expression in Inflammatory Trachomatous Scarring

(2013) Tamsyn Derrick et al.   PLoS Neglected Tropical Diseases

Trachoma: Protective and Pathogenic Ocular Immune Responses to Chlamydia trachomatis

(2013) Victor H. Hu et al.   PLoS Neglected Tropical Diseases

IL-22 Mediates Goblet Cell Hyperplasia and Worm Expulsion in Intestinal Helminth Infection

(2013) Jan-Eric Turner et al.   PLoS Pathogens

Antibiotic development challenges: the various mechanisms of action of antimicrobial peptides and of bacterial resistance

(2013) Fernanda Guilhelmelli et al.   Frontiers in Microbiology

Sex differences matter in the gut: effect on mucosal immune activation and inflammation

(2013) Sumathi Sankaran-Walters et al.   Biology of Sex Differences

Causes of vision loss worldwide, 1990–2010: a systematic analysis

(2013) Rupert R A Bourne et al.   Lancet Global Health

Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β

(2012) Christina E. Zielinski et al.   NATURE

Post-Operative Recurrent Trachomatous Trichiasis Is Associated with Increased Conjunctival Expression of S100A7 (Psoriasin)

(2012) Matthew J. Burton et al.   PLoS Neglected Tropical Diseases

Essential Role for Neutrophils in Pathogenesis and Adaptive Immunity in Chlamydia caviae Ocular Infections

(2011) H. Marie Lacy et al.   INFECTION AND IMMUNITY

Innate Immune Responses and Modified Extracellular Matrix Regulation Characterize Bacterial Infection and Cellular/Connective Tissue Changes in Scarring Trachoma

(2011) Victor H. Hu et al.   INFECTION AND IMMUNITY

Active Trachoma Is Associated with Increased Conjunctival Expression ofIL17Aand Profibrotic Cytokines

(2011) Matthew J. Burton et al.   INFECTION AND IMMUNITY

Enhanced Neutrophil Longevity and Recruitment Contribute to the Severity of Oviduct Pathology during Chlamydia muridarum Infection

(2011) Lauren C. Frazer et al.   INFECTION AND IMMUNITY

Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5

(2011) Xiang-Ping Yang et al.   NATURE IMMUNOLOGY

Protective immunity against mouse upper genital tract pathology correlates with high IFNγ but low IL-17 T cell and anti-secretion protein antibody responses induced by replicating chlamydial organisms in the airway

(2011) Chunxue Lu et al.   VACCINE

Correlation of Clinical Trachoma and Infection in Aboriginal Communities

(2011) Claude-Edouard C. Michel et al.   PLoS Neglected Tropical Diseases

Systemic effector and regulatory immune responses to chlamydial antigens in trachomatous trichiasis

(2011) Gall   Frontiers in Microbiology

Differentiation of Effector CD4 T Cell Populations

(2010) Jinfang Zhu et al.   Annual Review of Immunology

Human Conjunctival Transcriptome Analysis Reveals the Prominence of Innate Defense in Chlamydia trachomatis Infection

(2010) A. Natividad et al.   INFECTION AND IMMUNITY

Conjunctival Transcriptome in Scarring Trachoma

(2010) Matthew J. Burton et al.   INFECTION AND IMMUNITY

IL-17 and IL-22: siblings, not twins

(2010) Stefanie Eyerich et al.   TRENDS IN IMMUNOLOGY

Stronger inflammatory/cytotoxic T-cell response in women identified by microarray analysis

(2009) A Hewagama et al.   GENES AND IMMUNITY

Th17 cells in human disease

(2008) Laura A. Tesmer et al.   IMMUNOLOGICAL REVIEWS

The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt

(2008) Nicolas Manel et al.   NATURE IMMUNOLOGY

Constant Ocular Infection with Chlamydia trachomatis Predicts Risk of Scarring in Children in Tanzania

(2008) Meraf A. Wolle et al.   OPHTHALMOLOGY

Role of Secreted Conjunctival Mucosal Cytokine and Chemokine Proteins in Different Stages of Trachomatous Disease

(2008) Troy A. Skwor et al.   PLoS Neglected Tropical Diseases

The Natural History of Trachoma Infection and Disease in a Gambian Cohort with Frequent Follow-Up

(2008) Nicholas C. Grassly et al.   PLoS Neglected Tropical Diseases