Fibroblasts profiling in scarring trachoma identifies IL-6 as a functional component of a fibroblast-macrophage pro-fibrotic and pro-inflammatory feedback loop

A Chlamydia effector recruits CEP170 to reprogram host microtubule organization

(2015) M. Dumoux et al.   JOURNAL OF CELL SCIENCE

Conjunctival fibrosis and the innate barriers to Chlamydia trachomatis intracellular infection: a genome wide association study

(2015) Chrissy h. Roberts et al.   Scientific Reports

Pathogenesis of Progressive Scarring Trachoma in Ethiopia and Tanzania and Its Implications for Disease Control: Two Cohort Studies

(2015) Matthew J. Burton et al.   PLoS Neglected Tropical Diseases

Interleukin-6 Signaling Drives Fibrosis in Unresolved Inflammation

(2014) Ceri A. Fielding et al.   IMMUNITY

Blockade of IL-6TransSignaling Attenuates Pulmonary Fibrosis

(2014) Thanh-Thuy T. Le et al.   JOURNAL OF IMMUNOLOGY

Tissue mechanics and fibrosis

(2013) Rebecca G. Wells   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

In vivo confocal microscopy and histopathology of the conjunctiva in trachomatous scarring and normal tissue: a systematic comparison

(2013) Victor H Hu et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

AP2α transcriptional activity is essential for retinoid-induced neuronal differentiation of mesenchymal stem cells

(2013) Yang Bi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts

(2013) Fernando Calvo et al.   NATURE CELL BIOLOGY

Trachoma: Protective and Pathogenic Ocular Immune Responses to Chlamydia trachomatis

(2013) Victor H. Hu et al.   PLoS Neglected Tropical Diseases

GO-Elite: a flexible solution for pathway and ontology over-representation

(2012) Alexander C. Zambon et al.   BIOINFORMATICS

The myofibroblast matrix: implications for tissue repair and fibrosis

(2012) Franco Klingberg et al.   JOURNAL OF PATHOLOGY

Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis

(2012) Alfiya Akhmetshina et al.   Nature Communications

Profibrotic Phenotype of Conjunctival Fibroblasts from Mucous Membrane Pemphigoid

(2011) Valerie P.J. Saw et al.   AMERICAN JOURNAL OF PATHOLOGY

Active Trachoma Is Associated with Increased Conjunctival Expression ofIL17Aand Profibrotic Cytokines

(2011) Matthew J. Burton et al.   INFECTION AND IMMUNITY

NCAM2/OCAM/RNCAM: Cell adhesion molecule with a role in neuronal compartmentalization

(2011) Malene Winther et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

A Role for Prolyl 3-Hydroxylase 2 in Post-translational Modification of Fibril-forming Collagens

(2011) Russell J. Fernandes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The effect of MMP inhibitor GM6001 on early fibroblast-mediated collagen matrix contraction is correlated to a decrease in cell protrusive activity

(2010) Belen Martin-Martin et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Human Conjunctival Transcriptome Analysis Reveals the Prominence of Innate Defense in Chlamydia trachomatis Infection

(2010) A. Natividad et al.   INFECTION AND IMMUNITY

Conjunctival Transcriptome in Scarring Trachoma

(2010) Matthew J. Burton et al.   INFECTION AND IMMUNITY

Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression

(2010) Fei Liu et al.   JOURNAL OF CELL BIOLOGY

Association of TNFSF4 (OX40L) polymorphisms with susceptibility to systemic sclerosis

(2009) P. Gourh et al.   ANNALS OF THE RHEUMATIC DISEASES

High-Throughput Measurements of Hydrogel Tissue Construct Mechanics

(2009) Juan Pablo Marquez et al.   TISSUE ENGINEERING PART C-METHODS

Signaling cross-talk between TGF-β/BMP and other pathways

(2008) Xing Guo et al.   CELL RESEARCH

Role of Secreted Conjunctival Mucosal Cytokine and Chemokine Proteins in Different Stages of Trachomatous Disease

(2008) Troy A. Skwor et al.   PLoS Neglected Tropical Diseases