Genetic evidence that Nkx2.2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development

Pancreatic β cell identity requires continual repression of non–β cell programs

(2016) Giselle Domínguez Gutiérrez et al.   JOURNAL OF CLINICAL INVESTIGATION

The Spatiotemporal Pattern of Glis3 Expression Indicates a Regulatory Function in Bipotent and Endocrine Progenitors during Early Pancreatic Development and in Beta, PP and Ductal Cells

(2016) Hong Soon Kang et al.   PLoS One

Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3

(2014) A. B. Osipovich et al.   DEVELOPMENT

Gene Ontology Consortium: going forward

(2014)   NUCLEIC ACIDS RESEARCH

Rfx6 Maintains the Functional Identity of Adult Pancreatic β Cells

(2014) Julie Piccand et al.   Cell Reports

Development of the Human Pancreas From Foregut to Endocrine Commitment

(2013) R. E. Jennings et al.   DIABETES

Gastrin: A Distinct Fate of Neurogenin3 Positive Progenitor Cells in the Embryonic Pancreas

(2013) Yaron Suissa et al.   PLoS One

Generation of mice encoding a conditional allele of Nkx2.2

(2013) Teresa L. Mastracci et al.   TRANSGENIC RESEARCH

Nkx6.1 Controls a Gene Regulatory Network Required for Establishing and Maintaining Pancreatic Beta Cell Identity

(2013) Ashleigh E. Schaffer et al.   PLoS Genetics

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

(2012) H. Thorvaldsdottir et al.   BRIEFINGS IN BIOINFORMATICS

Identification and analysis of murine pancreatic islet enhancers

(2012) B. R. Tennant et al.   DIABETOLOGIA

Generation of Nkx2.2:lacZ mice using recombination-mediated cassette exchange technology

(2012) Luis Arnes et al.   GENESIS

Ghrelin Expression in the Mouse Pancreas Defines a Unique Multipotent Progenitor Population

(2012) Luis Arnes et al.   PLoS One

Nkx2.2 and Arx genetically interact to regulate pancreatic endocrine cell development and endocrine hormone expression

(2011) Teresa L. Mastracci et al.   DEVELOPMENTAL BIOLOGY

Pancreas organogenesis: From bud to plexus to gland

(2011) Fong Cheng Pan et al.   DEVELOPMENTAL DYNAMICS

Nkx2.2 repressor complex regulates islet  -cell specification and prevents  -to- -cell reprogramming

(2011) J. B. Papizan et al.   GENES & DEVELOPMENT

Integrative genomics viewer

(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

Rfx6 directs islet formation and insulin production in mice and humans

(2010) Stuart B. Smith et al.   NATURE

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

Identification of known and novel pancreas genes expressed downstream of Nkx2.2 during development

(2009) Keith R Anderson et al.   BMC DEVELOPMENTAL BIOLOGY

Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development

(2009) Josselin Soyer et al.   DEVELOPMENT

Pancreatic neurogenin 3-expressing cells are unipotent islet precursors

(2009) R. Desgraz et al.   DEVELOPMENT

Cooperative Transcriptional Regulation of the Essential Pancreatic Islet GeneNeuroD1(Beta2) by Nkx2.2 and Neurogenin 3

(2009) Keith R. Anderson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Pdx-1 and Ptf1a concurrently determine fate specification of pancreatic multipotent progenitor cells

(2008) Jared S. Burlison et al.   DEVELOPMENTAL BIOLOGY