The somatically generated portion of T cell receptor CDR3α contributes to the MHC allele specificity of the T cell receptor

Hydrophobic CDR3 residues promote the development of self-reactive T cells

(2016) Brian D Stadinski et al.   NATURE IMMUNOLOGY

Class II major histocompatibility complex mutant mice to study the germ-line bias of T-cell antigen receptors

(2016) Daniel Silberman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of shared TCR sequences from T cells in human breast cancer using emulsion RT-PCR

(2016) Daniel J. Munson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TCR  repertoire of CD4+ and CD8+ T cells is distinct in richness, distribution, and CDR3 amino acid composition

(2015) H. M. Li et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A discrete chromatin loop in the mouse Tcra-Tcrd locus shapes the TCRδ and TCRα repertoires

(2015) Liang Chen et al.   NATURE IMMUNOLOGY

Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity

(2015) Jarrett J Adams et al.   NATURE IMMUNOLOGY

The RAG Recombinase Dictates Functional Heterogeneity and Cellular Fitness in Natural Killer Cells

(2014) Jenny M. Karo et al.   CELL

High-throughput sequencing of natively paired antibody chains provides evidence for original antigenic sin shaping the antibody response to influenza vaccination

(2014) Yann-Chong Tan et al.   CLINICAL IMMUNOLOGY

Revisiting Thymic Positive Selection and the Mature T Cell Repertoire for Antigen

(2014) Nienke Vrisekoop et al.   IMMUNITY

Lymphocyte repertoire selection and intracellular self/non-self-discrimination: historical overview

(2014) Donald R Forsdyke   IMMUNOLOGY AND CELL BIOLOGY

Cell competition is a tumour suppressor mechanism in the thymus

(2014) Vera C. Martins et al.   NATURE

Characterization of human αβTCR repertoire and discovery of D-D fusion in TCRβ chains

(2014) Peipei Liu et al.   Protein & Cell

High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire

(2013) Brandon J DeKosky et al.   NATURE BIOTECHNOLOGY

Murine thymic selection quantified using a unique method to capture deleted T cells

(2013) G. L. Stritesky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proposing a resolution to debates on diversity partitioning

(2012) Anne Chao et al.   ECOLOGY

Highly diverse TCRα chain repertoire of pre-immune CD8+T cells reveals new insights in gene recombination

(2012) Raphael Genolet et al.   EMBO JOURNAL

Next generation sequencing for TCR repertoire profiling: Platform-specific features and correction algorithms

(2012) Dmitry A. Bolotin et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Structural and dynamic control of T-cell receptor specificity, cross-reactivity, and binding mechanism

(2012) Brian M. Baker et al.   IMMUNOLOGICAL REVIEWS

Elevated and sustained expression of the transcription factors Egr1 and Egr2 controls NKT lineage differentiation in response to TCR signaling

(2012) Michael P Seiler et al.   NATURE IMMUNOLOGY

Exhaustive T-cell repertoire sequencing of human peripheral blood samples reveals signatures of antigen selection and a directly measured repertoire size of at least 1 million clonotypes

(2011) R. L. Warren et al.   GENOME RESEARCH

T cell receptor signal strength in Tregand iNKT cell development demonstrated by a novel fluorescent reporter mouse

(2011) Amy E. Moran et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Mechanism for TCR Sharing between T Cell Subsets and Individuals Revealed by Pyrosequencing

(2011) Vanessa Venturi et al.   JOURNAL OF IMMUNOLOGY

Orchestrating T-cell receptor α gene assembly through changes in chromatin structure and organization

(2010) Han-Yu Shih et al.   IMMUNOLOGIC RESEARCH

Overlap and Effective Size of the Human CD8+ T Cell Receptor Repertoire

(2010) H. S. Robins et al.   Science Translational Medicine

Profiling the T-cell receptor beta-chain repertoire by massively parallel sequencing

(2009) J. D. Freeman et al.   GENOME RESEARCH

Germline-encoded amino acids in the αβ T-cell receptor control thymic selection

(2009) James P. Scott-Browne et al.   NATURE

An endogenous peptide positively selects and augments the activation and survival of peripheral CD4+ T cells

(2009) Wan-Lin Lo et al.   NATURE IMMUNOLOGY

An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a

(2009) Peter J R Ebert et al.   NATURE IMMUNOLOGY

Where Do MAIT Cells Fit in the Family of Unconventional T Cells?

(2009) Laurent Gapin   PLOS BIOLOGY

Crossreactive T Cells Spotlight the Germline Rules for αβ T Cell-Receptor Interactions with MHC Molecules

(2008) Shaodong Dai et al.   IMMUNITY

A Biochemically Defined System for Coding Joint Formation in V(D)J Recombination

(2008) Haihui Lu et al.   MOLECULAR CELL

T cell allorecognition and MHC restriction—A case of Jekyll and Hyde?

(2007) Julia K. Archbold et al.   MOLECULAR IMMUNOLOGY