Structural insight into the activation of a class B G-protein-coupled receptor by peptide hormones in live human cells
出版年份 2017 全文链接
标题
Structural insight into the activation of a class B G-protein-coupled receptor by peptide hormones in live human cells
作者
关键词
-
出版物
eLife
Volume 6, Issue -, Pages -
出版商
eLife Sciences Organisation, Ltd.
发表日期
2017-08-03
DOI
10.7554/elife.27711
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Phase-plate cryo-EM structure of a class B GPCR–G-protein complex
- (2017) Yi-Lynn Liang et al. NATURE
- Structure of the full-length glucagon class B G-protein-coupled receptor
- (2017) Haonan Zhang et al. NATURE
- Non-peptide CRF-Receptor Antagonists: Allosterism, Kinetics and Translation to Efficacy in Human Disease
- (2017) Samuel R.J. Hoare et al. Current Molecular Pharmacology
- Understanding Corticotropin Releasing Factor Receptor (CRFR) Activation Using Structural Models
- (2017) Arnau Cordomi et al. Current Molecular Pharmacology
- Allostery and Biased Agonism at Class B G Protein-Coupled Receptors
- (2016) Denise Wootten et al. CHEMICAL REVIEWS
- Use of Cysteine Trapping to Map Spatial Approximations between Residues Contributing to the Helix N-capping Motif of Secretin and Distinct Residues within Each of the Extracellular Loops of Its Receptor
- (2016) Maoqing Dong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Allosteric coupling from G protein to the agonist-binding pocket in GPCRs
- (2016) Brian T. DeVree et al. NATURE
- Extra-helical binding site of a glucagon receptor antagonist
- (2016) Ali Jazayeri et al. NATURE
- CHARMM-GUI Input Generator for NAMD, GROMACS, AMBER, OpenMM, and CHARMM/OpenMM Simulations Using the CHARMM36 Additive Force Field
- (2015) Jumin Lee et al. Journal of Chemical Theory and Computation
- Generic GPCR residue numbers – aligning topology maps while minding the gaps
- (2015) Vignir Isberg et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Conformational states of the full-length glucagon receptor
- (2015) Linlin Yang et al. Nature Communications
- Transmembrane signal transduction by peptide hormones via family B G protein-coupled receptors
- (2015) Kelly J. Culhane et al. Frontiers in Pharmacology
- Proximity-Enabled Protein Crosslinking through Genetically Encoding Haloalkane Unnatural Amino Acids
- (2014) Zheng Xiang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Structure of Class B GPCRs: new horizons for drug discovery
- (2014) Andrea Bortolato et al. BRITISH JOURNAL OF PHARMACOLOGY
- Allosteric sodium in class A GPCR signaling
- (2014) Vsevolod Katritch et al. TRENDS IN BIOCHEMICAL SCIENCES
- CRF and urocortin peptides as modulators of energy balance and feeding behavior during stress
- (2014) Andreas Stengel et al. Frontiers in Neuroscience
- Structural and functional insights into the juxtamembranous amino-terminal tail and extracellular loop regions of class B GPCRs
- (2013) M Dong et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Dynamic Process of β2-Adrenergic Receptor Activation
- (2013) Rie Nygaard et al. CELL
- Genetically Encoded Chemical Probes in Cells Reveal the Binding Path of Urocortin-I to CRF Class B GPCR
- (2013) Irene Coin et al. CELL
- Corticotropin-releasing factor peptide antagonists: Design, characterization and potential clinical relevance
- (2013) Jean E. Rivier et al. FRONTIERS IN NEUROENDOCRINOLOGY
- Structure of class B GPCR corticotropin-releasing factor receptor 1
- (2013) Kaspar Hollenstein et al. NATURE
- Structure of the human glucagon class B G-protein-coupled receptor
- (2013) Fai Yiu Siu et al. NATURE
- Adding an unnatural covalent bond to proteins through proximity-enhanced bioreactivity
- (2013) Zheng Xiang et al. NATURE METHODS
- Polar transmembrane interactions drive formation of ligand-specific and signal pathway-biased family B G protein-coupled receptor conformations
- (2013) D. Wootten et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Insights into the structure of class B GPCRs
- (2013) Kaspar Hollenstein et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Structure and mechanism for recognition of peptide hormones by Class B G-protein-coupled receptors
- (2012) Kuntal Pal et al. ACTA PHARMACOLOGICA SINICA
- Lifting the lid on GPCRs: the role of extracellular loops
- (2012) M Wheatley et al. BRITISH JOURNAL OF PHARMACOLOGY
- Optimization of the Additive CHARMM All-Atom Protein Force Field Targeting Improved Sampling of the Backbone ϕ, ψ and Side-Chain χ1 and χ2 Dihedral Angles
- (2012) Robert B. Best et al. Journal of Chemical Theory and Computation
- Predicted structure of agonist-bound glucagon-like peptide 1 receptor, a class B G protein-coupled receptor
- (2012) A. Kirkpatrick et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Photo-Cross-Linkers Incorporated into G-Protein-Coupled Receptors in Mammalian Cells: A Ligand Comparison
- (2011) Irene Coin et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Members of CRF Family and their Receptors: From Past to Future
- (2011) G. Liapakis et al. CURRENT MEDICINAL CHEMISTRY
- Second Extracellular Loop of Human Glucagon-like Peptide-1 Receptor (GLP-1R) Has a Critical Role in GLP-1 Peptide Binding and Receptor Activation
- (2011) Cassandra Koole et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Refinement of Glucagon-like Peptide 1 Docking to Its Intact Receptor Using Mid-region Photolabile Probes and Molecular Modeling
- (2011) Laurence J. Miller et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Crystal structure of the β2 adrenergic receptor–Gs protein complex
- (2011) Søren G. F. Rasmussen et al. NATURE
- NMR Structure of the First Extracellular Domain of Corticotropin-releasing Factor Receptor 1 (ECD1-CRF-R1) Complexed with a High Affinity Agonist
- (2010) Christy Rani R. Grace et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Red-emitting luciferases for bioluminescence reporter and imaging applications
- (2009) Bruce R. Branchini et al. ANALYTICAL BIOCHEMISTRY
- Alanine Scanning Mutagenesis of the Second Extracellular Loop of Type 1 Corticotropin-Releasing Factor Receptor Revealed Residues Critical for Peptide Binding
- (2009) K. Gkountelias et al. MOLECULAR PHARMACOLOGY
- Mapping Peptide Hormone−Receptor Interactions Using a Disulfide-Trapping Approach†
- (2008) Paul Monaghan et al. BIOCHEMISTRY
- Molecular Recognition of Corticotropin-releasing Factor by Its G-protein-coupled Receptor CRFR1
- (2008) Augen A. Pioszak et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation
- (2008) Berk Hess et al. Journal of Chemical Theory and Computation
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation