Structure and mechanism for recognition of peptide hormones by Class B G-protein-coupled receptors

Crystal Structure of the PAC1R Extracellular Domain Unifies a Consensus Fold for Hormone Recognition by Class B G-Protein Coupled Receptors

(2011) Shiva Kumar et al.   PLoS One

Conformational and molecular interaction studies of glucagon-like peptide-2 with its N-terminal extracellular receptor domain

(2010) Kalyana C. Venneti et al.   FEBS LETTERS

Dimeric Arrangement of the Parathyroid Hormone Receptor and a Structural Mechanism for Ligand-induced Dissociation

(2010) Augen A. Pioszak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis for Hormone Recognition by the Human CRFR2α G Protein-coupled Receptor

(2010) Kuntal Pal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NMR Structure of the First Extracellular Domain of Corticotropin-releasing Factor Receptor 1 (ECD1-CRF-R1) Complexed with a High Affinity Agonist

(2010) Christy Rani R. Grace et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The evolving place of incretin-based therapies in type 2 diabetes

(2010) Baptist Gallwitz   PEDIATRIC NEPHROLOGY

Formation and dissociation of M1 muscarinic receptor dimers seen by total internal reflection fluorescence imaging of single molecules

(2010) J. A. Hern et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structure of the Ectodomain Complex of the CGRP Receptor, a Class-B GPCR, Reveals the Site of Drug Antagonism

(2010) Ernst ter Haar et al.   STRUCTURE

Ligand-regulated oligomerization of β2-adrenoceptors in a model lipid bilayer

(2009) Juan José Fung et al.   EMBO JOURNAL

Structural Basis for Parathyroid Hormone-related Protein Binding to the Parathyroid Hormone Receptor and Design of Conformation-selective Peptides

(2009) Augen A. Pioszak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of Glucagon-like Peptide-1 in Complex with the Extracellular Domain of the Glucagon-like Peptide-1 Receptor

(2009) Christina Rye Underwood et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The TIP39–PTH2 receptor system: Unique peptidergic cell groups in the brainstem and their interactions with central regulatory mechanisms

(2009) Arpád Dobolyi et al.   PROGRESS IN NEUROBIOLOGY

A  -Arrestin-Biased Agonist of the Parathyroid Hormone Receptor (PTH1R) Promotes Bone Formation Independent of G Protein Activation

(2009) D. Gesty-Palmer et al.   Science Translational Medicine

Passing the baton in class B GPCRs: peptide hormone activation via helix induction?

(2009) Christoph Parthier et al.   TRENDS IN BIOCHEMICAL SCIENCES

C-terminal mini-PEGylation of glucose-dependent insulinotropic polypeptide exhibits metabolic stability and improved glucose homeostasis in dietary-induced diabetes

(2008) Victor A. Gault et al.   BIOCHEMICAL PHARMACOLOGY

Molecular Recognition of Corticotropin-releasing Factor by Its G-protein-coupled Receptor CRFR1

(2008) Augen A. Pioszak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of the Ligand-bound Glucagon-like Peptide-1 Receptor Extracellular Domain

(2008) Steffen Runge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pattern of Intra-Family Hetero-Oligomerization Involving the G-Protein-Coupled Secretin Receptor

(2008) Kaleeckal G. Harikumar et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to GPCR oligomerization

(2008) Damien Maurel et al.   NATURE METHODS

Structural diversity of G protein-coupled receptors and significance for drug discovery

(2008) Malin C. Lagerström et al.   NATURE REVIEWS DRUG DISCOVERY

Urocortin2 inhibits tumor growth via effects on vascularization and cell proliferation

(2008) Z. Hao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular recognition of parathyroid hormone by its G protein-coupled receptor

(2008) Augen A. Pioszak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of the human receptor activity-modifying protein 1 extracellular domain

(2008) Seisuke Kusano et al.   PROTEIN SCIENCE

Class-B GPCR activation: is ligand helix-capping the key?

(2008) Jean-Michel Neumann et al.   TRENDS IN BIOCHEMICAL SCIENCES

How and why do GPCRs dimerize?

(2008) Vsevolod V. Gurevich et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Novel glycosylated VIP analogs: synthesis, biological activity, and metabolic stability

(2007) David Dangoor et al.   JOURNAL OF PEPTIDE SCIENCE