Tri-methylation of H3K79 is decreased in TGF-β1-induced epithelial-to-mesenchymal transition in lung cancer
出版年份 2017 全文链接
标题
Tri-methylation of H3K79 is decreased in TGF-β1-induced epithelial-to-mesenchymal transition in lung cancer
作者
关键词
Lung cancer, NSCLC, EMT, H3K79me3, DOT1L, PD-L1, SEMA3C, NRP2, Epigenetic treatment
出版物
Clinical Epigenetics
Volume 9, Issue 1, Pages -
出版商
Springer Nature
发表日期
2017-08-08
DOI
10.1186/s13148-017-0380-0
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- EMT: 2016
- (2016) M. Angela Nieto et al. CELL
- The upstreams and downstreams of H3K79 methylation by DOT1L
- (2016) Hanneke Vlaming et al. CHROMOSOMA
- The Bromodomain Inhibitor JQ1 and the Histone Deacetylase Inhibitor Panobinostat Synergistically Reduce N-Myc Expression and Induce Anticancer Effects
- (2016) J. Shahbazi et al. CLINICAL CANCER RESEARCH
- A Novel Epigenetic Signature for Early Diagnosis in Lung Cancer
- (2016) A. Diaz-Lagares et al. CLINICAL CANCER RESEARCH
- Epithelial-Mesenchymal Transition Is Associated with a Distinct Tumor Microenvironment Including Elevation of Inflammatory Signals and Multiple Immune Checkpoints in Lung Adenocarcinoma
- (2016) Y. Lou et al. CLINICAL CANCER RESEARCH
- Prognostic Significance of PD-L1 in Patients with Non–Small Cell Lung Cancer: A Large Cohort Study of Surgically Resected Cases
- (2016) Jong-Mu Sun et al. Journal of Thoracic Oncology
- Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas
- (2016) Joshua D Campbell et al. NATURE GENETICS
- Epithelial–mesenchymal transition: a new target in anticancer drug discovery
- (2016) Fabrizio Marcucci et al. NATURE REVIEWS DRUG DISCOVERY
- Functional interdependence of BRD4 and DOT1L in MLL leukemia
- (2016) Omer Gilan et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- MYC regulates the antitumor immune response through CD47 and PD-L1
- (2016) S. C. Casey et al. SCIENCE
- The role of the semaphorins in cancer
- (2016) Gera Neufeld et al. Cell Adhesion & Migration
- Functional interdependence of BRD4 and DOT1L in MLL leukemia
- (2016) Omer Gilan et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Targeting histone methyltransferases and demethylases in clinical trials for cancer therapy
- (2016) Ludovica Morera et al. Clinical Epigenetics
- Regulation of PD-L1: a novel role of pro-survival signalling in cancer
- (2015) J. Chen et al. ANNALS OF ONCOLOGY
- Molecular Portraits of Epithelial, Mesenchymal, and Hybrid States in Lung Adenocarcinoma and Their Relevance to Survival
- (2015) M. J. Schliekelman et al. CANCER RESEARCH
- Neuropilin-2 Regulates Endosome Maturation and EGFR Trafficking to Support Cancer Cell Pathobiology
- (2015) Samikshan Dutta et al. CANCER RESEARCH
- Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth
- (2015) Sonja Kleffel et al. CELL
- The 2015 World Health Organization Classification of Lung Tumors
- (2015) William D. Travis et al. Journal of Thoracic Oncology
- Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
- (2015) Xiaofeng Zheng et al. NATURE
- Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
- (2015) Kari R. Fischer et al. NATURE
- Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma
- (2015) Pawel K Mazur et al. NATURE MEDICINE
- DOT1L cooperates with the c-Myc-p300 complex to epigenetically derepress CDH1 transcription factors in breast cancer progression
- (2015) Min-Hyung Cho et al. Nature Communications
- Regulation of mTOR Signaling by Semaphorin 3F-Neuropilin 2 Interactions In Vitro and In Vivo
- (2015) Hironao Nakayama et al. Scientific Reports
- RE-IIBP Methylates H3K79 and Induces MEIS1-mediated Apoptosis via H2BK120 Ubiquitination by RNF20
- (2015) Jin Woo Park et al. Scientific Reports
- Neuropilins are multifunctional coreceptors involved in tumor initiation, growth, metastasis and immunity
- (2015) Gerald J Prud'homme et al. Oncotarget
- EBV-driven LMP1 and IFN-γ up-regulate PD-L1 in nasopharyngeal carcinoma: Implications for oncotargeted therapy
- (2015) Wenfeng Fang et al. Oncotarget
- Development of PD-1/PD-L1 Pathway in Tumor Immune Microenvironment and Treatment for Non-Small Cell Lung Cancer
- (2015) Jiabei He et al. Scientific Reports
- Targeted therapy of epigenomic regulatory mechanisms controlling the epithelial to mesenchymal transition during tumor progression
- (2014) Vivek Kumar Mishra et al. CELL AND TISSUE RESEARCH
- The emerging roles of DOT1L in leukemia and normal development
- (2014) C M McLean et al. LEUKEMIA
- Comprehensive molecular profiling of lung adenocarcinoma
- (2014) Eric A. Collisson et al. NATURE
- Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression
- (2014) Limo Chen et al. Nature Communications
- Lung cancer epigenetics: emerging biomarkers
- (2013) Ioanna Balgkouranidou et al. Biomarkers in Medicine
- Potent inhibition of DOT1L as treatment of MLL-fusion leukemia
- (2013) S. R. Daigle et al. BLOOD
- Neuropilin-2 Is Upregulated in Lung Cancer Cells during TGF- 1-Induced Epithelial-Mesenchymal Transition
- (2013) P. Nasarre et al. CANCER RESEARCH
- A Synthetic Lethality-Based Strategy to Treat Cancers Harboring a Genetic Deficiency in the Chromatin Remodeling Factor BRG1
- (2013) T. Oike et al. CANCER RESEARCH
- EZH2 Protein Expression Associates with the Early Pathogenesis, Tumor Progression, and Prognosis of Non-Small Cell Lung Carcinoma
- (2013) C. Behrens et al. CLINICAL CANCER RESEARCH
- The role of semaphorins and their receptors in vascular development and cancer
- (2013) Chenghua Gu et al. EXPERIMENTAL CELL RESEARCH
- Programmed death ligand-1 expression in non-small cell lung cancer
- (2013) Vamsidhar Velcheti et al. LABORATORY INVESTIGATION
- lncRNA-dependent mechanisms of androgen-receptor-regulated gene activation programs
- (2013) Liuqing Yang et al. NATURE
- The epigenetics of epithelial-mesenchymal plasticity in cancer
- (2013) Wai Leong Tam et al. NATURE MEDICINE
- Epigenetic coordination of signaling pathways during the epithelial-mesenchymal transition
- (2013) Marcin Cieślik et al. Epigenetics & Chromatin
- Global Decrease of Histone H3K27 Acetylation in ZEB1-Induced Epithelial to Mesenchymal Transition in Lung Cancer Cells
- (2013) Joëlle Roche et al. Cancers
- Epigenetic biomarkers in lung cancer
- (2012) Triantafillos Liloglou et al. CANCER LETTERS
- Lung cancer with loss of BRG1/BRM, shows epithelial mesenchymal transition phenotype and distinct histologic and genetic features
- (2012) Daisuke Matsubara et al. CANCER SCIENCE
- Tumor B7-H1 and B7-H3 Expression in Squamous Cell Carcinoma of the Lung
- (2012) Jennifer M. Boland et al. Clinical Lung Cancer
- The enigmatic role of H2Bub1 in cancer
- (2012) Steven A. Johnsen FEBS LETTERS
- Epigenetic protein families: a new frontier for drug discovery
- (2012) Cheryl H. Arrowsmith et al. NATURE REVIEWS DRUG DISCOVERY
- Semaphorins in cancer: Biological mechanisms and therapeutic approaches
- (2012) Michael Rehman et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Chromatin modifications as therapeutic targets in MLL-rearranged leukemia
- (2012) Aniruddha J. Deshpande et al. TRENDS IN IMMUNOLOGY
- Enhancer of zeste homolog 2 is a novel prognostic biomarker in nonsmall cell lung cancer
- (2011) Huqun et al. CANCER
- Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker
- (2011) Masashi Takawa et al. CANCER SCIENCE
- Neuropilin-2 Mediated β-Catenin Signaling and Survival in Human Gastro-Intestinal Cancer Cell Lines
- (2011) Shaija Samuel et al. PLoS One
- Distinctive expression of the polycomb group proteins Bmi1 polycomb ring finger oncogene and enhancer of zeste homolog 2 in nonsmall cell lung cancers and their clinical and clinicopathologic significance
- (2010) Junko Kikuchi et al. CANCER
- ZEB1-responsive genes in non-small cell lung cancer
- (2010) Robert M. Gemmill et al. CANCER LETTERS
- The PD-1 pathway in tolerance and autoimmunity
- (2010) Loise M. Francisco et al. IMMUNOLOGICAL REVIEWS
- Lung cancer
- (2010) Arnaud Van Den Broeck et al. Cell Adhesion & Migration
- Guidance molecules in lung cancer
- (2010) Patrick Nasarre et al. Cell Adhesion & Migration
- Epithelial-Mesenchymal Transitions in Development and Disease
- (2009) Jean Paul Thiery et al. CELL
- The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
- (2008) Sendurai A. Mani et al. CELL
- DOT1L/KMT4 Recruitment and H3K79 Methylation Are Ubiquitously Coupled with Gene Transcription in Mammalian Cells
- (2008) D. J. Steger et al. MOLECULAR AND CELLULAR BIOLOGY
- Nonprocessive methylation by Dot1 leads to functional redundancy of histone H3K79 methylation states
- (2008) Floor Frederiks et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
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