标题
Cancer Immunotherapy Using CAR-T Cells: From the Research Bench to the Assembly Line
作者
关键词
-
出版物
Biotechnology Journal
Volume 13, Issue 2, Pages 1700097
出版商
Wiley
发表日期
2017-09-28
DOI
10.1002/biot.201700097
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cord blood NK cells engineered to express IL-15 and a CD19-targeted CAR show long-term persistence and potent antitumor activity
- (2017) E Liu et al. LEUKEMIA
- Engineering Natural Killer Cells for Cancer Immunotherapy
- (2017) Katayoun Rezvani et al. MOLECULAR THERAPY
- Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection
- (2017) Justin Eyquem et al. NATURE
- Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells
- (2017) Waseem Qasim et al. Science Translational Medicine
- Transgenic Expression of IL15 Improves Antiglioma Activity of IL13Rα2-CAR T Cells but Results in Antigen Loss Variants
- (2017) Giedre Krenciute et al. Cancer Immunology Research
- T cells expressing an anti-B-cell maturation antigen chimeric antigen receptor cause remissions of multiple myeloma
- (2016) S. A. Ali et al. BLOOD
- CD19-targeted CAR T-cell therapeutics for hematologic malignancies: interpreting clinical outcomes to date
- (2016) Jae H. Park et al. BLOOD
- A Chimeric Switch-Receptor Targeting PD1 Augments the Efficacy of Second-Generation CAR T Cells in Advanced Solid Tumors
- (2016) Xiaojun Liu et al. CANCER RESEARCH
- CD19-Targeted chimeric antigen receptor-modified T-cell immunotherapy for B-cell malignancies
- (2016) CJ Turtle et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Myeloid cells in peripheral blood mononuclear cell concentrates inhibit the expansion of chimeric antigen receptor T cells
- (2016) David F. Stroncek et al. CYTOTHERAPY
- Automated manufacturing of chimeric antigen receptor T cells for adoptive immunotherapy using CliniMACS Prodigy
- (2016) Ulrike Mock et al. CYTOTHERAPY
- CD19-CAR engineered NK-92 cells are sufficient to overcome NK cell resistance in B-cell malignancies
- (2016) Annette Romanski et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- CD19 CAR–T cells of defined CD4+:CD8+ composition in adult B cell ALL patients
- (2016) Cameron J. Turtle et al. JOURNAL OF CLINICAL INVESTIGATION
- Enhanced CAR T-cell engineering using non-viral Sleeping Beauty transposition from minicircle vectors
- (2016) R Monjezi et al. LEUKEMIA
- Switching CAR T cells on and off: a novel modular platform for retargeting of T cells to AML blasts
- (2016) M Cartellieri et al. Blood Cancer Journal
- CRISPR-Cas9 mediated efficient PD-1 disruption on human primary T cells from cancer patients
- (2016) Shu Su et al. Scientific Reports
- Platelet glycoprotein VI binds to polymerized fibrin and promotes thrombin generation
- (2015) E. Mammadova-Bach et al. BLOOD
- Multiplex Genome-Edited T-cell Manufacturing Platform for “Off-the-Shelf” Adoptive T-cell Immunotherapies
- (2015) Laurent Poirot et al. CANCER RESEARCH
- Human Epidermal Growth Factor Receptor 2 (HER2) –Specific Chimeric Antigen Receptor–Modified T Cells for the Immunotherapy of HER2-Positive Sarcoma
- (2015) Nabil Ahmed et al. JOURNAL OF CLINICAL ONCOLOGY
- Treatment of CD33-directed Chimeric Antigen Receptor-modified T Cells in One Patient With Relapsed and Refractory Acute Myeloid Leukemia
- (2015) Quan-shun Wang et al. MOLECULAR THERAPY
- 4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors
- (2015) Adrienne H Long et al. NATURE MEDICINE
- Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia
- (2015) David L. Porter et al. Science Translational Medicine
- Engineering CAR-T cells: Design concepts
- (2015) Shivani Srivastava et al. TRENDS IN IMMUNOLOGY
- Present and Future of Allogeneic Natural Killer Cell Therapy
- (2015) Okjae Lim et al. Frontiers in Immunology
- Adoptive Therapy With Chimeric Antigen Receptor–Modified T Cells of Defined Subset Composition
- (2014) Stanley R. Riddell et al. CANCER JOURNAL
- Effects of cryopreservation on effector cells for antibody dependent cell-mediated cytotoxicity (ADCC) and natural killer (NK) cell activity in 51Cr-release and CD107a assays
- (2014) Mariana M. Mata et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Reversal of Tumor Immune Inhibition Using a Chimeric Cytokine Receptor
- (2014) Ann M Leen et al. MOLECULAR THERAPY
- The business case for cell and gene therapies
- (2014) Mohamed Abou-El-Enein et al. NATURE BIOTECHNOLOGY
- Qualification of academic facilities for small-scale automated manufacture of autologous cell-based products
- (2014) Paul Hourd et al. Regenerative Medicine
- Cancer Immunotherapy Based on Mutation-Specific CD4+ T Cells in a Patient with Epithelial Cancer
- (2014) E. Tran et al. SCIENCE
- The Nonsignaling Extracellular Spacer Domain of Chimeric Antigen Receptors Is Decisive for In Vivo Antitumor Activity
- (2014) M. Hudecek et al. Cancer Immunology Research
- A Novel Approach to Manufacture CAR-T Cells for Clinical Applications
- (2013) Pradip Bajgain et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- T Lymphocytes Expressing a CD16 Signaling Receptor Exert Antibody-Dependent Cancer Cell Killing
- (2013) K. Kudo et al. CANCER RESEARCH
- Biosafety Features of Lentiviral Vectors
- (2013) Axel Schambach et al. HUMAN GENE THERAPY
- Patient monitoring and follow-up in lentiviral clinical trials
- (2013) Gerard J. McGarrity et al. JOURNAL OF GENE MEDICINE
- Persistence and Efficacy of Second Generation CAR T Cell Against the LeY Antigen in Acute Myeloid Leukemia
- (2013) David S. Ritchie et al. MOLECULAR THERAPY
- Disparate Individual Fates Compose Robust CD8+ T Cell Immunity
- (2013) V. R. Buchholz et al. SCIENCE
- Heterogeneous Differentiation Patterns of Individual CD8+ T Cells
- (2013) C. Gerlach et al. SCIENCE
- TCR-Engineered T Cells Meet New Challenges to Treat Solid Tumors: Choice of Antigen, T Cell Fitness, and Sensitization of Tumor Milieu
- (2013) Andre Kunert et al. Frontiers in Immunology
- Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning
- (2012) H. J. Pegram et al. BLOOD
- CD20-specific adoptive immunotherapy for lymphoma using a chimeric antigen receptor with both CD28 and 4-1BB domains: pilot clinical trial results
- (2012) B. G. Till et al. BLOOD
- Decade-Long Safety and Function of Retroviral-Modified Chimeric Antigen Receptor T Cells
- (2012) J. Scholler et al. Science Translational Medicine
- Bioreactors get personal
- (2012) Robert P.T. Somerville et al. OncoImmunology
- Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma
- (2011) C. U. Louis et al. BLOOD
- Durable Complete Responses in Heavily Pretreated Patients with Metastatic Melanoma Using T-Cell Transfer Immunotherapy
- (2011) S. A. Rosenberg et al. CLINICAL CANCER RESEARCH
- Infusing CD19-Directed T Cells to Augment Disease Control in Patients Undergoing Autologous Hematopoietic Stem-Cell Transplantation for Advanced B-Lymphoid Malignancies
- (2011) Partow Kebriaei et al. HUMAN GENE THERAPY
- Human effector CD8+ T cells derived from naive rather than memory subsets possess superior traits for adoptive immunotherapy
- (2010) C. S. Hinrichs et al. BLOOD
- Combination of IL-21 and IL-15 enhances tumour-specific cytotoxicity and cytokine production of TCR-transduced primary T cells
- (2010) Nadine Pouw et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Enhanced Tumor Trafficking of GD2 Chimeric Antigen Receptor T Cells by Expression of the Chemokine Receptor CCR2b
- (2010) John A. Craddock et al. JOURNAL OF IMMUNOTHERAPY
- Accelerated Production of Antigen-specific T Cells for Preclinical and Clinical Applications Using Gas-permeable Rapid Expansion Cultureware (G-Rex)
- (2010) Juan F. Vera et al. JOURNAL OF IMMUNOTHERAPY
- Different regulation of MHC Class I antigen processing components in human tumors
- (2009) Barbara Seliger Journal of Immunotoxicology
- IL-7 and IL-15 allow the generation of suicide gene-modified alloreactive self-renewing central memory human T lymphocytes
- (2008) S. Kaneko et al. BLOOD
- Adoptive immunotherapy using human peripheral blood lymphocytes transferred with RNA encoding Her-2/neu-specific chimeric immune receptor in ovarian cancer xenograft model
- (2008) S H Yoon et al. CANCER GENE THERAPY
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