Integrated Genome and Protein Editing Swaps α -2,6 Sialylation for α -2,3 Sialic Acid on Recombinant Antibodies from CHO

Enhanced sialylation of a human chimeric IgG1 variant produced in human and rodent cell lines

(2016) Yusuke Mimura et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Assessment of the coordinated role of ST3GAL3, ST3GAL4 and ST3GAL6 on the α2,3 sialylation linkage of mammalian glycoproteins

(2015) Cheng-Yu Chung et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Glycoengineering of Chinese hamster ovary cells for enhanced erythropoietin N-glycan branching and sialylation

(2015) Bojiao Yin et al.   BIOTECHNOLOGY AND BIOENGINEERING

Production of α2,6-sialylated IgG1 in CHO cells

(2015) Céline Raymond et al.   mAbs

Engineered CHO cells for production of diverse, homogeneous glycoproteins

(2015) Zhang Yang et al.   NATURE BIOTECHNOLOGY

A common glycan structure on immunoglobulin G for enhancement of effector functions

(2015) Chin-Wei Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protection in antibody- and T cell-mediated autoimmune diseases by antiinflammatory IgG Fcs requires type II FcRs

(2015) Benjamin M. Fiebiger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

QUANTITY: An Isobaric Tag for Quantitative Glycomics

(2015) Shuang Yang et al.   Scientific Reports

Glycoengineered Monoclonal Antibodies with Homogeneous Glycan (M3, G0, G2, and A2) Using a Chemoenzymatic Approach Have Different Affinities for FcγRIIIa and Variable Antibody-Dependent Cellular Cytotoxicity Activities

(2015) Masaki Kurogochi et al.   PLoS One

Accelerating genome editing in CHO cells using CRISPR Cas9 and CRISPy, a web-based target finding tool

(2014) Carlotta Ronda et al.   BIOTECHNOLOGY AND BIOENGINEERING

The therapeutic monoclonal antibody market

(2014) Dawn M Ecker et al.   mAbs

A tool kit for rapid cloning and expression of recombinant antibodies

(2014) Tihomir S. Dodev et al.   Scientific Reports

Glycomic Analysis Using Glycoprotein Immobilization for Glycan Extraction

(2013) Shuang Yang et al.   ANALYTICAL CHEMISTRY

Engineering Hydrophobic Protein–Carbohydrate Interactions to Fine-Tune Monoclonal Antibodies

(2013) Xiaojie Yu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Chemoenzymatic Glycoengineering of Intact IgG Antibodies for Gain of Functions

(2012) Wei Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sialylation Determines the Nephritogenicity of IgG3 Cryoglobulins

(2012) M. Otani et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line

(2011) Xun Xu et al.   NATURE BIOTECHNOLOGY

Recapitulation of IVIG Anti-Inflammatory Activity with a Recombinant IgG Fc

(2008) R. M. Anthony et al.   SCIENCE