The self-sufficient P450 RhF expressed in a whole cell system selectively catalyses the 5-hydroxylation of diclofenac

Subtle structural changes in the Asp251Gly/Gln307His P450 BM3 mutant responsible for new activity toward diclofenac, tolbutamide and ibuprofen

(2016) Giovanna Di Nardo et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Process development for oxidations of hydrophobic compounds applying cytochrome P450 monooxygenases in-vitro

(2016) Jan Brummund et al.   JOURNAL OF BIOTECHNOLOGY

Enabling Selective and Sustainable P450 Oxygenation Technology. Production of 4-Hydroxy-α-isophorone on Kilogram Scale

(2016) Iwona Kaluzna et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Characterization of cytochrome P450 isoforms involved in sequential two-step bioactivation of diclofenac to reactive p-benzoquinone imines

(2016) Michiel W. den Braver et al.   TOXICOLOGY LETTERS

Guidelines for development and implementation of biocatalytic P450 processes

(2015) Marie T. Lundemo et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Drug Oxidation by Cytochrome P450BM3: Metabolite Synthesis and Discovering New P450 Reaction Types

(2015) Xinkun Ren et al.   CHEMISTRY-A EUROPEAN JOURNAL

Water Analysis: Emerging Contaminants and Current Issues

(2014) Susan D. Richardson et al.   ANALYTICAL CHEMISTRY

Cytochromes P450 as promising catalysts for biotechnological application: chances and limitations

(2014) Rita Bernhardt et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Simultaneous determination of diclofenac, its human metabolites and microbial nitration/nitrosation transformation products in wastewaters by liquid chromatography/quadrupole-linear ion trap mass spectrometry

(2014) Victoria Osorio et al.   JOURNAL OF CHROMATOGRAPHY A

Engineering and application of P450 monooxygenases in pharmaceutical and metabolite synthesis

(2013) Jill M Caswell et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Evaluation of three industrial Escherichia coli strains in fed-batch cultivations during high-level SOD protein production

(2013) Karoline Marisch et al.   Microbial Cell Factories

High-level semi-synthetic production of the potent antimalarial artemisinin

(2013) C. J. Paddon et al.   NATURE

Substrate promiscuity of cytochrome P450 RhF

(2013) Elaine O'Reilly et al.   Catalysis Science & Technology

Identification of Mutant Asp251Gly/Gln307His of Cytochrome P450 BM3 for the Generation of Metabolites of Diclofenac, Ibuprofen and Tolbutamide

(2012) Georgia E. Tsotsou et al.   CHEMISTRY-A EUROPEAN JOURNAL

Occurrence of pharmaceutical compounds in wastewater and sludge from wastewater treatment plants: Removal and ecotoxicological impact of wastewater discharges and sludge disposal

(2012) J. Martín et al.   JOURNAL OF HAZARDOUS MATERIALS

Controlled Oxidation of Remote sp3 C–H Bonds in Artemisinin via P450 Catalysts with Fine-Tuned Regio- and Stereoselectivity

(2012) Kaidong Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cytochromes P450 as useful biocatalysts: addressing the limitations

(2011) Elaine O'Reilly et al.   CHEMICAL COMMUNICATIONS

Regio- and stereoselectivity of P450-catalysed hydroxylation of steroids controlled by laboratory evolution

(2011) Sabrina Kille et al.   Nature Chemistry

Convenient Gram-Scale Metabolite Synthesis by Engineered Fission Yeast Strains Expressing Functional Human P450 Systems

(2010) Călin-Aurel Drăgan et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

LICRED: A Versatile Drop-In Vector for Rapid Generation of Redox-Self-Sufficient Cytochrome P450s

(2010) Federico Sabbadin et al.   CHEMBIOCHEM

The CYPome of Sorangium cellulosum So ce56 and Identification of CYP109D1 as a New Fatty Acid Hydroxylase

(2010) Yogan Khatri et al.   CHEMISTRY & BIOLOGY

Input of selected human pharmaceuticalmetabolites into the Norwegian aquatic environment

(2010) Katherine Langford et al.   JOURNAL OF ENVIRONMENTAL MONITORING

P450BM-3-catalyzed whole-cell biotransformation of α-pinene with recombinant Escherichia coli in an aqueous–organic two-phase system

(2009) Hendrik Schewe et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

A Panel of Cytochrome P450 BM3 Variants to Produce Drug Metabolites and Diversify Lead Compounds

(2009) Andrew M. Sawayama et al.   CHEMISTRY-A EUROPEAN JOURNAL

Occurrence of diclofenac and its metabolites in surface water and effluent samples from Karachi, Pakistan

(2009) M. Scheurell et al.   CHEMOSPHERE

Different Biochemical Mechanisms Ensure Network-Wide Balancing of Reducing Equivalents in Microbial Metabolism

(2009) T. Fuhrer et al.   JOURNAL OF BACTERIOLOGY

Understanding and Improving NADPH-Dependent Reactions by Nongrowing Escherichia coli Cells

(2004) Adam Z. Walton et al.   BIOTECHNOLOGY PROGRESS