MiRNA-Sequence Indicates That Mesenchymal Stem Cells and Exosomes Have Similar Mechanism to Enhance Cardiac Repair

Rationale and design of the allogeneiC human mesenchymal stem cells (hMSC) in patients with aging fRAilTy via intravenoUS delivery (CRATUS) study: A phase I/II, randomized, blinded and placebo controlled trial to evaluate the safety and potential efficacy of allogeneic human mesenchymal stem cell infusion in patients with aging frailty

(2016) Samuel Golpanian et al.   Oncotarget

Pretreatment of Cardiac Stem Cells With Exosomes Derived From Mesenchymal Stem Cells Enhances Myocardial Repair

(2016) Zhiwei Zhang et al.   Journal of the American Heart Association

Mesenchymal Stem Cell-Derived Exosomes Improve the Microenvironment of Infarcted Myocardium Contributing to Angiogenesis and Anti-Inflammation

(2015) Xiaomei Teng et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Transport of microRNAs via exosomes

(2015) Yangxin Li et al.   Nature Reviews Cardiology

Exosomes for Intramyocardial Intercellular Communication

(2015) Elisabetta Cervio et al.   Stem Cells International

Cross Talk of Combined Gene and Cell Therapy in Ischemic Heart Disease: Role of Exosomal MicroRNA Transfer

(2014) S.-G. Ong et al.   CIRCULATION

Cardiac fibroblast–derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy

(2014) Claudia Bang et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNAs in myocardial infarction

(2014) Reinier A. Boon et al.   Nature Reviews Cardiology

Preconditioning of Mesenchymal Stem Cells by Sevoflurane to Improve Their Therapeutic Potential

(2014) Xuejun Sun et al.   PLoS One

MiR-378 Controls Cardiac Hypertrophy by Combined Repression of Mitogen-Activated Protein Kinase Pathway Factors

(2013) Jayavarshni Ganesan et al.   CIRCULATION

Cell Therapy for Heart Failure

(2013) Santosh K. Sanganalmath et al.   CIRCULATION RESEARCH

Extracellular vesicles derived from human bone marrow mesenchymal stem cells promote angiogenesis in a rat myocardial infarction model

(2013) Suyan Bian et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

MicroRNA-34a regulates cardiac ageing and function

(2013) Reinier A. Boon et al.   NATURE

Priming with Ligands Secreted by Human Stromal Progenitor Cells Promotes Grafts of Cardiac Stem/Progenitor Cells After Myocardial Infarction

(2013) Yoshitaka Iso et al.   STEM CELLS

MicroRNA-1/133 targeted dysfunction of potassium channels KCNE1 and KCNQ1 in human cardiac progenitor cells with simulated hyperglycemia

(2012) Yangxin Li et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Comparison of Allogeneic vs Autologous Bone Marrow–Derived Mesenchymal Stem Cells Delivered by Transendocardial Injection in Patients With Ischemic Cardiomyopathy

(2012) Joshua M. Hare et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Coculture with hematopoietic stem cells protects cardiomyocytes against apoptosis via paracrine activation of AKT

(2012) Mark Rosenberg et al.   Journal of Translational Medicine

Mesenchymal Stem Cells Secrete Multiple Cytokines That Promote Angiogenesis and Have Contrasting Effects on Chemotaxis and Apoptosis

(2012) Robert A. Boomsma et al.   PLoS One

Systemic Preconditioning by a Prolyl Hydroxylase Inhibitor Promotes Prevention of Skin Flap Necrosis via HIF-1-Induced Bone Marrow-Derived Cells

(2012) Mitsuru Takaku et al.   PLoS One

Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function

(2012) B. C. Bernardo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exosomes From Human CD34 + Stem Cells Mediate Their Proangiogenic Paracrine Activity

(2011) Susmita Sahoo et al.   CIRCULATION RESEARCH

Inhibition of miR-15 Protects Against Cardiac Ischemic Injury

(2011) Thomas G. Hullinger et al.   CIRCULATION RESEARCH

Morphologic and proteomic characterization of exosomes released by cultured extravillous trophoblast cells

(2011) Safinur Atay et al.   EXPERIMENTAL CELL RESEARCH

TGF-β signaling in fibrosis

(2011) Anna Biernacka et al.   GROWTH FACTORS

miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes

(2011) Li Qian et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Suppression of microRNA-29 Expression by TGF- 1 Promotes Collagen Expression and Renal Fibrosis

(2011) B. Wang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Bone Marrow Mesenchymal Stem Cells Stimulate Cardiac Stem Cell Proliferation and Differentiation

(2010) Konstantinos E. Hatzistergos et al.   CIRCULATION RESEARCH

Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins

(2010) Caroline Subra et al.   JOURNAL OF LIPID RESEARCH

Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury

(2010) Ruenn Chai Lai et al.   Stem Cell Research

Cardiac Progenitor Cells and Biotinylated Insulin-Like Growth Factor-1 Nanofibers Improve Endogenous and Exogenous Myocardial Regeneration After Infarction

(2009) M. Elena Padin-Iruegas et al.   CIRCULATION

Cardiomyocyte VEGFR-1 activation by VEGF-B induces compensatory hypertrophy and preserves cardiac function after myocardial infarction

(2009) Lorena Zentilin et al.   FASEB JOURNAL

A Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Study of Intravenous Adult Human Mesenchymal Stem Cells (Prochymal) After Acute Myocardial Infarction

(2009) Joshua M. Hare et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

MHC independent anti-tumor immune responses induced by Hsp70-enriched exosomes generate tumor regression in murine models

(2008) Jung-ah Cho et al.   CANCER LETTERS

Immunophenotype characterization of rat mesenchymal stromal cells

(2008) M.T. Harting et al.   CYTOTHERAPY