Shiga Toxins Induce Apoptosis and ER Stress in Human Retinal Pigment Epithelial Cells

Shiga Toxins as Multi-Functional Proteins: Induction of Host Cellular Stress Responses, Role in Pathogenesis and Therapeutic Applications

(2016) Moo-Seung Lee et al.   Toxins

Shiga Toxins Activate the NLRP3 Inflammasome Pathway To Promote Both Production of the Proinflammatory Cytokine Interleukin-1β and Apoptotic Cell Death

(2015) Moo-Seung Lee et al.   INFECTION AND IMMUNITY

Blinded by Shiga Toxin-Producing O104 Escherichia coli and Hemolytic Uremic Syndrome

(2014) Sjoukje E. Loudon et al.   JOURNAL OF PEDIATRICS

Lipid requirements for entry of protein toxins into cells

(2014) Kirsten Sandvig et al.   PROGRESS IN LIPID RESEARCH

Hemolytic uremic syndrome

(2014) Caterina Mele et al.   Seminars in Immunopathology

Distinct Renal Pathology and a Chemotactic Phenotype after Enterohemorrhagic Escherichia coli Shiga Toxins in Non-Human Primate Models of Hemolytic Uremic Syndrome

(2013) Deborah J. Stearns-Kurosawa et al.   AMERICAN JOURNAL OF PATHOLOGY

ER stress-induced cell death mechanisms

(2013) Renata Sano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Understanding age-related macular degeneration (AMD): Relationships between the photoreceptor/retinal pigment epithelium/Bruch’s membrane/choriocapillaris complex

(2012) Imran Bhutto et al.   MOLECULAR ASPECTS OF MEDICINE

Shiga Toxin 1 Induces on Lipopolysaccharide-Treated Astrocytes the Release of Tumor Necrosis Factor-alpha that Alter Brain-Like Endothelium Integrity

(2012) Verónica I. Landoni et al.   PLoS Pathogens

Activation of cell stress response pathways by Shiga toxins

(2011) Vernon L. Tesh   CELLULAR MICROBIOLOGY

Differential Response of the Human Renal Proximal Tubular Epithelial Cell Line HK-2 to Shiga Toxin Types 1 and 2

(2011) Erin K. Lentz et al.   INFECTION AND IMMUNITY

Mouse Models ofEscherichia coliO157:H7 Infection and Shiga Toxin Injection

(2011) Krystle L. Mohawk et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Protein toxins from plants and bacteria: Probes for intracellular transport and tools in medicine

(2010) Kirsten Sandvig et al.   FEBS LETTERS

Induction of apoptosis by Shiga toxins

(2010) Vernon L Tesh   Future Microbiology

Signaling through C/EBP Homologous Protein and Death Receptor 5 and Calpain Activation Differentially Regulate THP-1 Cell Maturation-Dependent Apoptosis Induced by Shiga Toxin Type 1

(2010) M.-S. Lee et al.   INFECTION AND IMMUNITY

BiP Binding to the ER-Stress Sensor Ire1 Tunes the Homeostatic Behavior of the Unfolded Protein Response

(2010) David Pincus et al.   PLOS BIOLOGY

Shiga Toxins: Intracellular Trafficking to the ER Leading to Activation of Host Cell Stress Responses

(2010) Moo-Seung Lee et al.   Toxins

Ocular involvement in paediatric haemolytic uraemic syndrome

(2009) Veit Sturm et al.   ACTA OPHTHALMOLOGICA

The Role of Mitochondria in Apoptosis

(2009) Chunxin Wang et al.   Annual Review of Genetics

Globotriaosyl ceramide receptor function - Where membrane structure and pathology intersect

(2009) C.A. Lingwood et al.   FEBS LETTERS

Bcl-2 Regulates the Onset of Shiga Toxin 1-Induced Apoptosis in THP-1 Cells

(2009) M.-S. Lee et al.   INFECTION AND IMMUNITY

Life and death of a BiP substrate

(2009) Joel H. Otero et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

ZAK: a MAP3Kinase that transduces Shiga toxin- and ricin-induced proinflammatory cytokine expression

(2008) Dakshina M. Jandhyala et al.   CELLULAR MICROBIOLOGY

Shiga toxin 1 induces apoptosis through the endoplasmic reticulum stress response in human monocytic cells

(2008) Sang-Yun Lee et al.   CELLULAR MICROBIOLOGY

Shiga Toxin 2 Causes Apoptosis in Human Brain Microvascular Endothelial Cells via C/EBP Homologous Protein

(2008) J. Fujii et al.   INFECTION AND IMMUNITY

Mouse Model of Hemolytic-Uremic Syndrome Caused by Endotoxin-Free Shiga Toxin 2 (Stx2) and Protection from Lethal Outcome by Anti-Stx2 Antibody

(2008) K. A. D. Sauter et al.   INFECTION AND IMMUNITY

Shiga Toxin 2 Affects the Central Nervous System through Receptor Globotriaosylceramide Localized to Neurons

(2008) Fumiko Obata et al.   JOURNAL OF INFECTIOUS DISEASES

Neuronal apoptosis and inflammatory responses in the central nervous system of a rabbit treated with Shiga toxin-2

(2008) Kiyomi Takahashi et al.   Journal of Neuroinflammation