Multiple UBXN family members inhibit retrovirus and lentivirus production and canonical NFκΒ signaling by stabilizing IκBα

Targeting NF-κB Signaling with Protein Kinase C Agonists As an Emerging Strategy for Combating HIV Latency

(2015) Guochun Jiang et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Understanding HIV Latency: The Road to an HIV Cure

(2015) Matthew S. Dahabieh et al.   Annual Review of Medicine

The N-terminal Region of the Ubiquitin Regulatory X (UBX) Domain-containing Protein 1 (UBXD1) Modulates Interdomain Communication within the Valosin-containing Protein p97

(2015) Franziska Trusch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ubiquitin-associated Domain-containing Ubiquitin Regulatory X (UBX) Protein UBXN1 Is a Negative Regulator of Nuclear Factor κB (NF-κB) Signaling

(2015) Yu-Bo Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Altered cofactor regulation with disease-associated p97/VCP mutations

(2015) Xiaoyi Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How Might We Cure HIV?

(2014) David M. Margolis   Current Infectious Disease Reports

From reactivation of latent HIV-1 to elimination of the latent reservoir: The presence of multiple barriers to viral eradication

(2013) Liang Shan et al.   BIOESSAYS

Innate Antiviral Immune Signaling, Viral Evasion and Modulation by HIV-1

(2013) Arjun Rustagi et al.   JOURNAL OF MOLECULAR BIOLOGY

UBXN1 Interferes with Rig-I-like Receptor-Mediated Antiviral Immune Response by Targeting MAVS

(2013) Penghua Wang et al.   Cell Reports

HIV Latency

(2013) R. F. Siliciano et al.   Cold Spring Harbor Perspectives in Medicine

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

The ORF2 glycoprotein of hepatitis E virus inhibits cellular NF-κB activity by blocking ubiquitination mediated proteasomal degradation of IκBα in human hepatoma cells

(2012) Milan Surjit et al.   BMC BIOCHEMISTRY

Activation of Latent HIV-1 Expression by Protein Kinase C Agonists. A Novel Therapeutic Approach to Eradicate HIV-1 Reservoirs

(2012) Gonzalo Sanchez-Duffhues et al.   CURRENT DRUG TARGETS

HIV-1, interferon and the interferon regulatory factor system: An interplay between induction, antiviral responses and viral evasion

(2012) Giulia Marsili et al.   CYTOKINE & GROWTH FACTOR REVIEWS

The development of immune-modulating compounds to disrupt HIV latency

(2012) Anna Lisa Remoli et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Human CRM1 Augments Production of Infectious Human and Feline Immunodeficiency Viruses from Murine Cells

(2012) H. Elinav et al.   JOURNAL OF VIROLOGY

Differential analysis of gene regulation at transcript resolution with RNA-seq

(2012) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Innate immune interferon responses to Human immunodeficiency virus-1 infection

(2012) Rose Hughes et al.   REVIEWS IN MEDICAL VIROLOGY

The Ubiquitin Regulatory X (UBX) Domain-containing Protein TUG Regulates the p97 ATPase and Resides at the Endoplasmic Reticulum-Golgi Intermediate Compartment

(2011) Charisse M. Orme et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Innate Antiviral Response: Role in HIV-1 Infection

(2011) Paula M. Pitha   Viruses-Basel

Caenorhabditis elegans UBX cofactors for CDC-48/p97 control spermatogenesis

(2010) Yohei Sasagawa et al.   GENES TO CELLS

The UBX Protein SAKS1 Negatively Regulates Endoplasmic Reticulum-associated Degradation and p97-dependent Degradation

(2010) David P. LaLonde et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The UBXN1 Protein Associates with Autoubiquitinated Forms of the BRCA1 Tumor Suppressor and Inhibits Its Enzymatic Function

(2010) Foon Wu-Baer et al.   MOLECULAR AND CELLULAR BIOLOGY

The Role of Ubiquitin in NF-κB Regulatory Pathways

(2009) Brian Skaug et al.   Annual Review of Biochemistry

UBXD1 is a VCP-interacting protein that is involved in ER-associated degradation

(2009) Masami Nagahama et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ABINs: A20 binding inhibitors of NF-κB and apoptosis signaling

(2009) Lynn Verstrepen et al.   BIOCHEMICAL PHARMACOLOGY

Isolation of Mammalian 26S Proteasomes and p97/VCP Complexes Using the Ubiquitin-like Domain from HHR23B Reveals Novel Proteasome-Associated Proteins†

(2009) Henrike C. Besche et al.   BIOCHEMISTRY

Ubx4 Modulates Cdc48 Activity and Influences Degradation of Misfolded Proteins of the Endoplasmic Reticulum

(2009) Sven M. Alberts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Understanding HIV-1 latency provides clues for the eradication of long-term reservoirs

(2009) Mayte Coiras et al.   NATURE REVIEWS MICROBIOLOGY

The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathology

(2009) Lars Vereecke et al.   TRENDS IN IMMUNOLOGY

Rotavirus NSP1 Inhibits NFκB Activation by Inducing Proteasome-Dependent Degradation of β-TrCP: A Novel Mechanism of IFN Antagonism

(2009) Joel W. Graff et al.   PLoS Pathogens

UBX domain proteins: major regulators of the AAA ATPase Cdc48/p97

(2008) C. Schuberth et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Titers of HIV-based Vectors Encoding shRNAs are Reduced by a Dicer-dependent Mechanism

(2007) Ananthalakshmi Poluri et al.   MOLECULAR THERAPY