Epistatic interaction between the lipase-encoding genes Pnpla2 and Lipe causes liposarcoma in mice

Dedifferentiated Liposarcoma

(2016) Khin Thway et al.   ADVANCES IN ANATOMIC PATHOLOGY

G0S2 Suppresses Oncogenic Transformation by Repressing a MYC-Regulated Transcriptional Program

(2016) C. Y. Yim et al.   CANCER RESEARCH

Notch activation drives adipocyte dedifferentiation and tumorigenic transformation in mice

(2016) Pengpeng Bi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Epigenetic re-expression of HIF-2α suppresses soft tissue sarcoma growth

(2016) Michael S. Nakazawa et al.   Nature Communications

Differentiation of 3T3-L1 preadipocytes is inhibited under a modified ceiling culture

(2015) Ziyi Song et al.   CELL BIOLOGY INTERNATIONAL

Alternative lengthening of telomeres and loss of ATRX are frequent events in pleomorphic and dedifferentiated liposarcomas

(2015) Jen-Chieh Lee et al.   MODERN PATHOLOGY

Cancer type-dependent genetic interactions between cancer driver alterations indicate plasticity of epistasis across cell types

(2015) S. Park et al.   Molecular Systems Biology

Possible inhibitory role of endogenous 2-arachidonoylglycerol as an endocannabinoid in (±)-epibatidine-induced activation of central adrenomedullary outflow in the rat

(2015) Takahiro Shimizu et al.   NEUROPHARMACOLOGY

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

Glycoprotein Nonmetastatic Melanoma B (Gpnmb)-Positive Macrophages Contribute to the Balance between Fibrosis and Fibrolysis during the Repair of Acute Liver Injury in Mice

(2015) Kotaro Kumagai et al.   PLoS One

STAT6 is amplified in a subset of dedifferentiated liposarcoma

(2014) Leona A Doyle et al.   MODERN PATHOLOGY

Synergistic Effects of Targeted PI3K Signaling Inhibition and Chemotherapy in Liposarcoma

(2014) Shang Guo et al.   PLoS One

Lipolysis in lipid turnover, cancer cachexia, and obesity-induced insulin resistance

(2014) Peter Arner et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Widespread genetic epistasis among cancer genes

(2014) Xiaoyue Wang et al.   Nature Communications

Loss of Abhd5 Promotes Colorectal Tumor Development and Progression by Inducing Aerobic Glycolysis and Epithelial-Mesenchymal Transition

(2014) Juanjuan Ou et al.   Cell Reports

Novel Dedifferentiated Liposarcoma Xenograft Models Reveal PTEN Down-Regulation as a Malignant Signature and Response to PI3K Pathway Inhibition

(2013) Kathleen B. Smith et al.   AMERICAN JOURNAL OF PATHOLOGY

The Cancer Genome Atlas Pan-Cancer analysis project

(2013) John N Weinstein et al.   NATURE GENETICS

Lipogenesis and lipolysis: The pathways exploited by the cancer cells to acquire fatty acids

(2013) Nousheen Zaidi et al.   PROGRESS IN LIPID RESEARCH

Copy Number Losses Define Subgroups of Dedifferentiated Liposarcoma with Poor Prognosis and Genomic Instability

(2012) Aimee M. Crago et al.   CLINICAL CANCER RESEARCH

Fasting Energy Homeostasis in Mice with Adipose Deficiency of Desnutrin/Adipose Triglyceride Lipase

(2012) Jiang Wei Wu et al.   ENDOCRINOLOGY

Dedifferentiated Liposarcoma With Lipoma-Like Well-Differentiated Liposarcoma

(2012) Yoko Iwasa et al.   INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY

Identification of a CpG Island Methylator Phenotype in Adrenocortical Carcinomas

(2012) Olivia Barreau et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth

(2011) Kristin M Nieman et al.   NATURE MEDICINE

Aberrant AKT activation drives well-differentiated liposarcoma

(2011) A. Gutierrez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The G0/G1 Switch Gene 2 Regulates Adipose Lipolysis through Association with Adipose Triglyceride Lipase

(2010) Xingyuan Yang et al.   Cell Metabolism

Transcriptional Switch of Dormant Tumors to Fast-Growing Angiogenic Phenotype

(2009) N. Almog et al.   CANCER RESEARCH

Monoacylglycerol Lipase Regulates a Fatty Acid Network that Promotes Cancer Pathogenesis

(2009) Daniel K. Nomura et al.   CELL

lumi: a pipeline for processing Illumina microarray

(2008) P. Du et al.   BIOINFORMATICS

Evidence for alternative lengthening of telomeres in liposarcomas in the absence of ALT-associated PML bodies

(2008) Jennie N. Jeyapalan et al.   INTERNATIONAL JOURNAL OF CANCER