Golgi anti-apoptotic protein: a tale of camels, calcium, channels and cancer

Lifeguard inhibition of Fas-mediated apoptosis: A possible mechanism for explaining the cisplatin resistance of triple-negative breast cancer cells

(2016) Daniel Radin et al.   BIOMEDICINE & PHARMACOTHERAPY

Variation at 2q35 (PNKDandTMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease

(2016) Giulia Orlando et al.   HUMAN MOLECULAR GENETICS

Investigation of membrane protein–protein interactions using correlative FRET-PLA

(2016) Daniel Ivanusic et al.   BIOTECHNIQUES

The transmembrane Bax inhibitor motif (TMBIM) containing protein family: Tissue expression, intracellular localization and effects on the ER CA2+-filling state

(2015) Dmitrij A. Lisak et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

BAX inhibitor-1 is a Ca2+ channel critically important for immune cell function and survival

(2015) D Lisak et al.   CELL DEATH AND DIFFERENTIATION

Lifeguard Inhibits Fas Ligand-mediated Endoplasmic Reticulum-Calcium Release Mandatory for Apoptosis in Type II Apoptotic Cells

(2015) Jorge Urresti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Golgi Anti-apoptotic Proteins Are Highly Conserved Ion Channels That Affect Apoptosis and Cell Migration

(2015) Guia Carrara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GOLPH3 Mediated Golgi Stress Response in Modulating N2A Cell Death upon Oxygen-Glucose Deprivation and Reoxygenation Injury

(2015) Ting Li et al.   MOLECULAR NEUROBIOLOGY

Expression Atlas update—an integrated database of gene and protein expression in humans, animals and plants

(2015) Robert Petryszak et al.   NUCLEIC ACIDS RESEARCH

Antiapoptotic Role for Lifeguard in T Cell Mediated Immune Response

(2015) Tatiana Hurtado de Mendoza et al.   PLoS One

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Inhibition of Translation Initiation by Protein 169: A Vaccinia Virus Strategy to Suppress Innate and Adaptive Immunity and Alter Virus Virulence

(2015) Pavla Strnadova et al.   PLoS Pathogens

Analysis of the anti-apoptotic activity of four vaccinia virus proteins demonstrates that B13 is the most potent inhibitor in isolation and during viral infection

(2014) D. L. Veyer et al.   JOURNAL OF GENERAL VIROLOGY

Pseudogenization of testis-specific Lfg5 predates human/Neanderthal divergence

(2014) Marco Mariotti et al.   JOURNAL OF HUMAN GENETICS

The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells

(2014) Julia Petschnigg et al.   NATURE METHODS

TMBIM protein family: ancestral regulators of cell death

(2014) D Rojas-Rivera et al.   ONCOGENE

Systematic Genetic Analysis Identifies Cis-eQTL Target Genes Associated with Glioblastoma Patient Survival

(2014) Qing-Rong Chen et al.   PLoS One

Structural basis for a pH-sensitive calcium leak across membranes

(2014) Y. Chang et al.   SCIENCE

MYCN repression of Lifeguard/FAIM2 enhances neuroblastoma aggressiveness

(2014) L Planells-Ferrer et al.   Cell Death & Disease

The minimalist architectures of viroporins and their therapeutic implications

(2013) Bo OuYang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

When ER stress reaches a dead end

(2013) Hery Urra et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Towards defining the chloroviruses: a genomic journey through a genus of large DNA viruses

(2013) Adrien Jeanniard et al.   BMC GENOMICS

Genome-Wide Association Study of Genetic Predictors of Overall Survival for Non–Small Cell Lung Cancer in Never Smokers

(2013) Xifeng Wu et al.   CANCER RESEARCH

Bax Inhibitor-1-mediated Ca2+ leak is decreased by cytosolic acidosis

(2013) Santeri Kiviluoto et al.   CELL CALCIUM

Human and Viral Golgi Anti-apoptotic Proteins (GAAPs) Oligomerize via Different Mechanisms and Monomeric GAAP Inhibits Apoptosis and Modulates Calcium

(2013) Nuno Saraiva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

hGAAP promotes cell adhesion and migration via the stimulation of store-operated Ca2+entry and calpain 2

(2013) Nuno Saraiva et al.   JOURNAL OF CELL BIOLOGY

Vaccinia virus immune evasion: mechanisms, virulence and immunogenicity

(2013) G. L. Smith et al.   JOURNAL OF GENERAL VIROLOGY

A CREB3–ARF4 signalling pathway mediates the response to Golgi stress and susceptibility to pathogens

(2013) Jan H. Reiling et al.   NATURE CELL BIOLOGY

Potassium Ion Channels: Could They Have Evolved from Viruses?

(2013) G. Thiel et al.   PLANT PHYSIOLOGY

Giant viruses coexisted with the cellular ancestors and represent a distinct supergroup along with superkingdoms Archaea, Bacteria and Eukarya

(2012) Arshan Nasir et al.   BMC EVOLUTIONARY BIOLOGY

TMBIM3/GRINA is a novel unfolded protein response (UPR) target gene that controls apoptosis through the modulation of ER calcium homeostasis

(2012) D Rojas-Rivera et al.   CELL DEATH AND DIFFERENTIATION

Six-transmembrane Topology for Golgi Anti-apoptotic Protein (GAAP) and Bax Inhibitor 1 (BI-1) Provides Model for the Transmembrane Bax Inhibitor-containing Motif (TMBIM) Family

(2012) Guia Carrara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Viroporins: structure and biological functions

(2012) José Luis Nieva et al.   NATURE REVIEWS MICROBIOLOGY

Phycodnavirus Potassium Ion Channel Proteins Question the Virus Molecular Piracy Hypothesis

(2012) Kay Hamacher et al.   PLoS One

Bax Inhibitor-1 is a novel IP3 receptor-interacting and -sensitizing protein

(2012) S Kiviluoto et al.   Cell Death & Disease

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The ancient cell death suppressor BAX inhibitor-1

(2011) Nadine Henke et al.   CELL CALCIUM

Lentivirus-Mediated RNA Interference Targeting Bax Inhibitor-1 Suppresses Ex Vivo Cell Proliferation and In Vivo Tumor Growth of Nasopharyngeal Carcinoma

(2011) Xiang-yong Li et al.   HUMAN GENE THERAPY

The C Terminus of Bax Inhibitor-1 Forms a Ca2+-permeable Channel Pore

(2011) Geert Bultynck et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIV-1 Vif Interaction with APOBEC3 Deaminases and its Characterization by a New Sensitive Assay

(2011) Iris Cadima-Couto et al.   Journal of Neuroimmune Pharmacology

Doxorubicin- and Daunorubicin-Induced Regulation of Ca2+ and H+ Fluxes Through Human Bax Inhibitor-1 Reconstituted into Membranes

(2011) Chul-ho Yun et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Antiapoptotic protein Lifeguard is required for survival and maintenance of Purkinje and granular cells

(2011) T. Hurtado de Mendoza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calcium store sensor stromal-interaction molecule 1-dependent signaling plays an important role in cervical cancer growth, migration, and angiogenesis

(2011) Y.-F. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A shear stress responsive gene product PP1201 protects against Fas-mediated apoptosis by reducing Fas expression on the cell surface

(2010) Sudhanshu Shukla et al.   APOPTOSIS

Viral proteins function as ion channels

(2010) Kai Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Integrating stress signals at the endoplasmic reticulum: The BCL-2 protein family rheostat

(2010) Diego Rodriguez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Overexpression of Bax inhibitor-1 (BI-1) induces cell transformation in NIH3T3 cells

(2010) Li Xiang‑yong et al.   CELL BIOLOGY INTERNATIONAL

Cardiolipin, phosphatidylserine, and BH4 domain of Bcl-2 family regulate Ca2+/H+ antiporter activity of human Bax inhibitor-1

(2010) Taeho Ahn et al.   CELL CALCIUM

Bax Inhibitor 1 Increases Cell Adhesion through Actin Polymerization: Involvement of Calcium and Actin Binding

(2010) G.-H. Lee et al.   MOLECULAR AND CELLULAR BIOLOGY

BAX inhibitor-1 enhances cancer metastasis by altering glucose metabolism and activating the sodium-hydrogen exchanger: the alteration of mitochondrial function

(2010) G-H Lee et al.   ONCOGENE

Phylogenetic and Phyletic Studies of Informational Genes in Genomes Highlight Existence of a 4th Domain of Life Including Giant Viruses

(2010) Mickaël Boyer et al.   PLoS One

LFG: a candidate apoptosis regulatory gene family

(2009) Lan Hu et al.   APOPTOSIS

Orai1 and STIM1 Are Critical for Breast Tumor Cell Migration and Metastasis

(2009) Shengyu Yang et al.   CANCER CELL

Ca2+/H+antiporter-like activity of human recombinant Bax inhibitor-1 reconstituted into liposomes

(2009) Taeho Ahn et al.   FEBS Journal

Human Golgi Antiapoptotic Protein Modulates Intracellular Calcium Fluxes

(2009) Fabrizio de Mattia et al.   MOLECULAR BIOLOGY OF THE CELL

BAX Inhibitor-1 Is a Negative Regulator of the ER Stress Sensor IRE1α

(2009) Fernanda Lisbona et al.   MOLECULAR CELL

Comparative genomics and function analysis on BI1 family

(2008) Jinhua Zhou et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

Bax Inhibitor-1 Is a pH-dependent Regulator of Ca2+Channel Activity in the Endoplasmic Reticulum

(2008) Hyung-Ryong Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a Novel Protein MICS1 that is Involved in Maintenance of Mitochondrial Morphology and Apoptotic Release of Cytochrome c

(2008) Toshihiko Oka et al.   MOLECULAR BIOLOGY OF THE CELL

Structural basis for the function and inhibition of an influenza virus proton channel

(2008) Amanda L. Stouffer et al.   NATURE

Organelle positioning and cell polarity

(2008) Michel Bornens   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ion Channels in Microbes

(2008) Boris Martinac et al.   PHYSIOLOGICAL REVIEWS

Chlorella viruses evoke a rapid release of K+ from host cells during the early phase of infection

(2007) Monika Neupärtl et al.   VIROLOGY