Golgi Anti-apoptotic Proteins Are Highly Conserved Ion Channels That Affect Apoptosis and Cell Migration

Pseudogenization of testis-specific Lfg5 predates human/Neanderthal divergence

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Systematic Genetic Analysis Identifies Cis-eQTL Target Genes Associated with Glioblastoma Patient Survival

(2014) Qing-Rong Chen et al.   PLoS One

Structural basis for a pH-sensitive calcium leak across membranes

(2014) Y. Chang et al.   SCIENCE

Bax Inhibitor-1 Is Likely a pH-Sensitive Calcium Leak Channel, Not a H+/Ca2+ Exchanger

(2014) G. Bultynck et al.   Science Signaling

The minimalist architectures of viroporins and their therapeutic implications

(2013) Bo OuYang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Genome-Wide Association Study of Genetic Predictors of Overall Survival for Non–Small Cell Lung Cancer in Never Smokers

(2013) Xifeng Wu et al.   CANCER RESEARCH

Human and Viral Golgi Anti-apoptotic Proteins (GAAPs) Oligomerize via Different Mechanisms and Monomeric GAAP Inhibits Apoptosis and Modulates Calcium

(2013) Nuno Saraiva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

hGAAP promotes cell adhesion and migration via the stimulation of store-operated Ca2+entry and calpain 2

(2013) Nuno Saraiva et al.   JOURNAL OF CELL BIOLOGY

Six-transmembrane Topology for Golgi Anti-apoptotic Protein (GAAP) and Bax Inhibitor 1 (BI-1) Provides Model for the Transmembrane Bax Inhibitor-containing Motif (TMBIM) Family

(2012) Guia Carrara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Viroporins: structure and biological functions

(2012) José Luis Nieva et al.   NATURE REVIEWS MICROBIOLOGY

COFACTOR: an accurate comparative algorithm for structure-based protein function annotation

(2012) Ambrish Roy et al.   NUCLEIC ACIDS RESEARCH

Bax Inhibitor-1 is a novel IP3 receptor-interacting and -sensitizing protein

(2012) S Kiviluoto et al.   Cell Death & Disease

The C Terminus of Bax Inhibitor-1 Forms a Ca2+-permeable Channel Pore

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Doxorubicin- and Daunorubicin-Induced Regulation of Ca2+ and H+ Fluxes Through Human Bax Inhibitor-1 Reconstituted into Membranes

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Viral proteins function as ion channels

(2010) Kai Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Overexpression of Bax inhibitor-1 (BI-1) induces cell transformation in NIH3T3 cells

(2010) Li Xiang‑yong et al.   CELL BIOLOGY INTERNATIONAL

Bax Inhibitor 1 Increases Cell Adhesion through Actin Polymerization: Involvement of Calcium and Actin Binding

(2010) G.-H. Lee et al.   MOLECULAR AND CELLULAR BIOLOGY

I-TASSER: a unified platform for automated protein structure and function prediction

(2010) Ambrish Roy et al.   Nature Protocols

BAX inhibitor-1 enhances cancer metastasis by altering glucose metabolism and activating the sodium-hydrogen exchanger: the alteration of mitochondrial function

(2010) G-H Lee et al.   ONCOGENE

A purified C-terminally truncated human adenosine A2A receptor construct is functionally stable and degradation resistant

(2010) Shweta Singh et al.   PROTEIN EXPRESSION AND PURIFICATION

LFG: a candidate apoptosis regulatory gene family

(2009) Lan Hu et al.   APOPTOSIS

Gating the pore of potassium leak channels

(2009) Asi Cohen et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Ca2+/H+antiporter-like activity of human recombinant Bax inhibitor-1 reconstituted into liposomes

(2009) Taeho Ahn et al.   FEBS Journal

Human Golgi Antiapoptotic Protein Modulates Intracellular Calcium Fluxes

(2009) Fabrizio de Mattia et al.   MOLECULAR BIOLOGY OF THE CELL

Cooperative nature of gating transitions in K+ channels as seen from dynamic importance sampling calculations

(2009) Elizabeth J. Denning et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

I-TASSER server for protein 3D structure prediction

(2008) Yang Zhang   BMC BIOINFORMATICS

The Bax Inhibitor-1 (BI-1) Family in Apoptosis and Tumorigenesis

(2008) Kerstin Reimers et al.   CURRENT MOLECULAR MEDICINE

Bax Inhibitor-1 Is a pH-dependent Regulator of Ca2+Channel Activity in the Endoplasmic Reticulum

(2008) Hyung-Ryong Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GFP-based optimization scheme for the overexpression and purification of eukaryotic membrane proteins in Saccharomyces cerevisiae

(2008) David Drew et al.   Nature Protocols