Article
Medicine, General & Internal
Qi Lu, Yanbo Zhang, Tingting Geng, Kun Yang, Kunquan Guo, Xinwen Min, Meian He, Huan Guo, Xiaomin Zhang, Handong Yang, Tangchun Wu, An Pan, Gang Liu
Summary: This study examined the joint association of antihypertensive medication use and healthy lifestyle with mortality among individuals with hypertension. The results showed that individuals with hypertension who used antihypertensive medication and had a healthy lifestyle had the lowest risk of all-cause, cardiovascular, and cancer mortality. Improvements in lifestyle score after hypertension diagnosis were also associated with lower risk of mortality.
Article
Nutrition & Dietetics
Wenxiu Wang, Jun Lv, Canqing Yu, Yu Guo, Pei Pei, Zhenhuang Zhuang, Ling Yang, Iona Y. Millwood, Robin G. Walters, Yiping Chen, Huaidong Du, Xianping Wu, Junshi Chen, Zhengming Chen, Robert Clarke, Tao Huang, Liming Li
Summary: Genetic predisposition to low birth weight and childhood obesity is associated with higher risk of adult T2D, but this risk can be reduced in adulthood by adherence to a healthy lifestyle, especially among those with high genetic risk of childhood obesity.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Public, Environmental & Occupational Health
Xi Yang, Kaushik Chattopadhyay, Richard Hubbard, Jia-Lin Li, Li Li, Yi Lin
Summary: A 36-month weight management programme in Ningbo, China showed that participants achieved significant initial weight loss at 3 months and maintained the weight loss during 33-month follow-ups. At 36 months, a certain percentage of participants achieved 5%, 10%, and 15% weight loss. The programme is suggested to benefit overweight and obese adults in reducing body weight and maintaining long-term weight loss.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Medicine, General & Internal
Lizeth Cifuentes, Wissam Ghusn, Fauzi Feris, Alejandro Campos, Daniel Sacoto, Alan De la Rosa, Alison McRae, Thom Rieck, Sara Mansfield, Jason Ewoldt, Jamie Friend, Karen Grothe, Ryan J. Lennon, Maria D. Hurtado, Matthew M. Clark, Michael Camilleri, Donald D. Hensrud, Andres Acosta
Summary: This study compared the outcome of a standard lifestyle intervention (SLI) to phenotype-tailored lifestyle interventions (PLI) for weight loss, cardiometabolic risk factors, and physiological variables contributing to obesity. The results showed that phenotype-tailored lifestyle interventions led to significant weight loss compared to standard interventions.
Article
Medicine, General & Internal
Jessica Gokee LaRose, Tricia M. Leahey, Autumn Lanoye, Melanie K. Bean, Joseph L. Fava, Deborah F. Tate, Ronald K. Evans, Edmond P. Wickham, Megan M. Henderson
Summary: In this randomized clinical trial, all interventions produced clinically significant benefit, but neither of the motivational enhancements promoted greater reductions in adiposity compared with the developmentally adapted standard group.
Article
Nutrition & Dietetics
Maria Kafyra, Ioanna P. Kalafati, Efthymia A. Katsareli, Sophia Lambrinou, Iraklis Varlamis, Andriana C. Kaliora, George Dedoussis
Summary: This study investigated the effect of gene-diet interactions on weight management in overweight and obese Greek adults through a randomized nutritional trial. Dietary patterns and a Lifestyle Index were found to be associated with anthropometric and biochemical indices, highlighting the importance of diet and lifestyle in weight management for this population.
Article
Food Science & Technology
Mohsen Mazidi, Emily R. Leeming, Jordi Merino, Long H. Nguyen, Somesh Selvachandran, Joan Capdavila Pujal, Tyler Maher, Kirstin Kade, Benjamin Murray, Mark S. Graham, Carole H. Sudre, Jonathan Wolf, Christina Hu, David A. Drew, Claire J. Steves, Sebastien Ourselin, Christopher Gardner, Tim D. Spector, Andrew T. Chan, Paul W. Franks, Rachel Gibson, Sarah E. Berry
Summary: Big data collected through mobile health apps shows that the COVID-19 pandemic has had diverse and extensive impacts on the diets and lifestyles of adults in the United States and the United Kingdom. The study found that disruption of health behaviors was higher in younger, female, and socio-economically deprived individuals, with greater weight loss observed in highly disrupted individuals.
Article
Endocrinology & Metabolism
Francis M. Finucane, Irene Gibson, Robert Hughes, Enda Murphy, Lisa Hynes, Aisling Harris, Brian E. McGuire, Mary Hynes, Chris Collins, Kevin Cradock, Suzanne Seery, Jennifer Jones, Tim O'Brien, Martin J. O'Donnell
Summary: In adults with severe obesity completing a structured lifestyle modification program, older age and good mental health were associated with program completion and achieving >= 5% weight loss. The amount of weight lost was a strong predictor of improvements in cardiovascular, metabolic, and mental health associated with program completion.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Medicine, General & Internal
Laura Heath, Susan A. Jebb, Paul Aveyard, Carmen Piernas
Summary: Controversial evidence suggests that obesity may not pose a risk to health if a person leads a healthy lifestyle and does not have any metabolic complications. This study aimed to investigate the relationship between adherence to healthy lifestyle recommendations and the absence of metabolic complications in relation to cardiovascular disease and mortality rates based on different body mass index (BMI) categories. The findings suggest that meeting healthy lifestyle recommendations or not having metabolic complications can partially offset the risk of developing cardiovascular disease and premature mortality in overweight or obese individuals. Therefore, offering support to achieve and maintain a healthy weight and adopt healthy behaviors is crucial in preventive healthcare.
Article
Multidisciplinary Sciences
Saara Laine, Tanja Sjoros, Taru Garthwaite, Maria Saarenhovi, Petri Kallio, Eliisa Loyttyniemi, Henri Vaha-Ypya, Harri Sievanen, Tommi Vasankari, Kirsi Laitinen, Noora Houttu, Ekaterina Saukko, Juhani Knuuti, Virva Saunavaara, Ilkka H. A. Heinonen
Summary: This study aimed to investigate the relationship between liver fat content (LFC) and sedentary behavior (SB), physical activity (PA), fitness, diet, body composition, and cardiometabolic risk factors in adults with metabolic syndrome. The results showed that LFC was positively associated with body fat and various cardiometabolic risk factors, and negatively associated with daily protein intake. SB, PA, or fitness were not independent modulators of LFC, but PA may indirectly affect liver health through its effects on body composition in adults with metabolic syndrome.
SCIENTIFIC REPORTS
(2022)
Article
Public, Environmental & Occupational Health
Ivo Vlaev, Michael J. Taylor, David Taylor, Paul Gately, Laura H. Gunn, Aliza Abeles, Abdelhamid Kerkadi, Jackie Lothian, Sahar Karim Jreige, Aziza Alsaadi, Mohamed G. Al-Kuwari, Suhaila Ghuloum, Hanan Al-Kuwari, Ara Darzi, Mohamed Ahmedna
Summary: The study evaluated the effectiveness of a weight management camp followed by a community intervention in supporting weight management for overweight and obese children. Results showed a significant reduction in BMI SDS for participants at both the individual and school levels, indicating the potential benefits of weekly lifestyle education and physical activity sessions for sustained weight management post-intervention.
Review
Endocrinology & Metabolism
Jack M. Birch, Rebecca A. Jones, Julia Mueller, Matthew D. McDonald, Rebecca Richards, Michael P. Kelly, Simon J. Griffin, Amy L. Ahern
Summary: This study conducted a systematic review on inequalities in behavioral weight management interventions trials, finding that most trials did not show an inequality gradient. However, when inequalities were observed, those with more advantages tended to perform better. Alternative methods of data synthesis may help in understanding inequalities in such interventions.
Article
Nutrition & Dietetics
Nuria Trujillo-Garrido, Maria J. Santi-Cano
Summary: This study analyzes the motivation, resources, and barriers to weight loss among patients with obesity in primary care. The findings show that a significant number of patients lack motivation to adhere to weight loss programs, and there is limited implementation of behavioral change interventions in primary care centers. Common barriers to adherence include lack of prescribed diet, joint pain, fatigue or boredom with dieting, and laziness.
Article
Public, Environmental & Occupational Health
Neha J. Pagidipati, Hillary Mulder, Karen Chiswell, Zachary Lampron, William S. Jones, Sriram Machineni, Lemuel R. Waitman, Morgana Mongraw-Chaffin, Fanta Waterman, Neela Kumar, Abhilasha Ramasamy, Gabriel Smolarz, Eric D. Peterson, Emily O'Brien
Summary: It remains uncertain whether individuals with overweight or obesity can lose weight and improve cardiometabolic risk factors over time in real-world settings. This study used data from 11 large health systems in the U.S. to investigate the management and degree of body weight change over 2 years among adults with BMI >= 25 kg/m2. The findings showed that the majority of individuals maintained stable weight, weight loss pharmacotherapy was under-utilized, and small improvements in cardiometabolic risk factors were not sustained.
PREVENTIVE MEDICINE
(2023)
Article
Nutrition & Dietetics
Cally Jennings, Elsie Patterson, Rachel G. Curtis, Anna Mazzacano, Carol A. Maher
Summary: The Healthy Eating Activity and Lifestyle program (HEAL(TM)) showed significant improvements in physical activity, diet, and health outcomes among rural residents, with high uptake and effectiveness rates.
Article
Psychology, Multidisciplinary
Siu-Ming Chan, Gary Ka-Ki Chung, Yat-Hang Chan, Jean Woo, Eng Kiong Yeoh, Roger Yat-Nork Chung, Samuel Yeung-Shan Wong, Michael Marmot, Richard Wai-Tong Lee, Hung Wong
Summary: This study examines the relationships between COVID-19 worries, social capital, mental health problems, and subjective well-being using structural equation modeling. The results show that worries during the pandemic have an impact on mental health and subjective well-being through the mediation of social capital. Additionally, the influence of social capital is stronger for the economically inactive group.
CURRENT PSYCHOLOGY
(2023)
Article
Gerontology
Dexia Kong, Peiyi Lu, Phyllis Solomon, Jean Woo, Mack Shelley
Summary: This study found that trajectories of depressive symptoms in one spouse are associated with the other spouse's memory. Spouses with increasing and persistently high depressive symptoms may experience worse memory, while spouses with decreasing depressive symptoms may have better memory.
JOURNAL OF AGING AND HEALTH
(2023)
Article
Nutrition & Dietetics
Ce Sun, Wei Sen Zhang, Chao Qiang Jiang, Ya Li Jin, Xue Qing Deng, G. Neil Thomas, Jean Woo, Kar Keung Cheng, Tai Hing Lam, Lin Xu
Summary: Using data from the Guangzhou Biobank Cohort Study, the association between whole grain and refined grain intake with all-cause, cancer, and cardiovascular disease mortality was examined. The study found that higher whole grain intake was associated with lower all-cause and cardiovascular disease mortality, while higher refined grain intake was associated with lower cancer mortality but higher cardiovascular disease mortality.
EUROPEAN JOURNAL OF NUTRITION
(2023)
Article
Sport Sciences
Danny J. Yu, Angus P. Yu, Shirley X. Li, Rachel N. Y. Chan, Daniel Y. Fong, Derwin K. C. Chan, Stanley S. Hui, Ka Fai Chung, Jean Woo, Chenchen Wang, Michael R. Irwin, Parco M. Siu
Summary: This study aims to compare the efficacy and long-term outcomes of Tai Chi and cognitive behavioral therapy for insomnia (CBT-I) in older adults. The participants will be randomly assigned to either the Tai Chi or CBT-I group, and the severity of insomnia will be assessed at 3 months and 15 months. This study is of clinical importance as it supports the use of Tai Chi as an alternative non-pharmacological approach for insomnia treatment.
JOURNAL OF EXERCISE SCIENCE & FITNESS
(2023)
Article
Endocrinology & Metabolism
Chi-Ho Lee, David Tak-Wai Lui, Raymond Hang-Wun Li, Michele Mae-Ann Yuen, Carol Ho-Yi Fong, Ambrose Pak-Wah Leung, Justin Chiu-Man Chu, Loey Lung-Yi Mak, Tai-Hing Lam, Jean Woo, Yu-Cho Woo, Aimin Xu, Hung-Fat Tse, Kathryn Choon-Beng Tan, Bernard Man-Yung Cheung, Man-Fung Yuen, Karen Siu-Ling Lam
Summary: This study investigated whether incorporating additional metabolic risk factors improved liver fibrosis risk stratification in non-diabetic overweight/obese MAFLD individuals. The results showed that abnormal AST and HOMA-IR levels were independently associated with higher liver fibrosis risk, and a sequential screening algorithm using these factors was developed for risk identification.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Geriatrics & Gerontology
Suey S. Y. Yeung, Timothy Kwok, Jean Woo
Summary: This study examined the association between baseline inflammation measured by hsCRP and the decline in muscle-related measures over a long period of time among Chinese community-dwelling older adults. The results showed that higher levels of hsCRP were associated with poorer handgrip strength and gait speed, but did not predict the decline in muscle-related measures.
ARCHIVES OF GERONTOLOGY AND GERIATRICS
(2023)
Article
Public, Environmental & Occupational Health
Eric T. C. Lai, Pui Hing Chau, Ken Cheung, Michelle Kwan, Kevin Lau, Jean Woo
Summary: Extreme hot weather events are becoming more frequent, intense, and long-lasting in Hong Kong. Older adults are particularly vulnerable to the heat stress which is associated with higher risk of mortality and morbidity. It is not known whether and how older adults perceive the increasingly hot weather as a health threat, and whether community service providers are prepared for future climate changes.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Health Care Sciences & Services
Gary Ka-Ki Chung, Mark Robinson, Michael Marmot, Jean Woo
Summary: In developed countries like the UK and Australia, addressing socioeconomic inequalities in health is a priority. However, in Hong Kong, the monitoring of socioeconomic inequalities in health is fragmented and the international practice of monitoring inequalities at area level is unsuitable. To improve inequality monitoring in Hong Kong, we can learn from the UK and Australia and explore the collection of health indicators and appropriate equity stratifiers, as well as strategies to promote public awareness and motivation for a comprehensive monitoring system.
LANCET REGIONAL HEALTH-WESTERN PACIFIC
(2023)
Article
Biochemistry & Molecular Biology
Erik Fung, Kwan Hung Ng, Timothy Kwok, Leong-Ting Lui, Saranya Palaniswamy, Queenie Chan, Lee-Ling Lim, Petri Wiklund, Suyi Xie, Cheryl Turner, Amany K. Elshorbagy, Helga Refsum, Jason C. S. Leung, Alice P. S. Kong, Juliana C. N. Chan, Marjo-Riitta Jarvelin, Jean Woo
Summary: Branched-chain amino acids can indicate the risk of cardiometabolic disease when increased or suggest sufficient energy metabolism and reserve in old age. The interpretation of BCAA levels can be context-dependent, and it remains unclear whether abnormal levels can inform prognosis. This study aimed to determine the interrelationship between mortality hazard and fasting serum BCAA levels among older men and women with or without hypertension and diabetes mellitus.
Article
Gerontology
Kar Him Mo, Esther Ng, Jean Woo, Rina Ko
Summary: This study examines the differences in perception of intergenerational living among three age categories of older adults: emerging old (aged 50-64), young-old (aged 65-79), and old-old (aged 80 and above). Survey results indicate that while all three age categories have similar perceptions of intergenerational living and its benefits, emerging old respondents are more receptive to various forms of intergenerational living compared to the other two age categories. The findings of this study can contribute to future housing solutions that better cater to the diverse needs of the older population.
JOURNAL OF AGING AND ENVIRONMENT
(2023)
Article
Geriatrics & Gerontology
Ruby Yu, G. Leung, D. Lai, C. Tong, L. Y. Tam, C. Cheng, S. Kong, J. Woo
Summary: Although integrated care is considered a key strategy in health system reform, particularly in medical social integration, it is challenging to implement in practice. This study aimed to investigate the capacity and role of social care professionals in implementing integrated care, as well as the barriers and facilitators identified by stakeholders. The findings suggest a gap in actualizing the integrated care approach within existing social service and care structures, but also support for the WHO ICOPE approach as a model for integrated care. Factors hindering and facilitating implementation include workforce capacity-building, coordinated networks and partnerships, and financial mechanisms.
JOURNAL OF FRAILTY & AGING
(2023)
Article
Geriatrics & Gerontology
R. Yu, D. Lai, G. Leung, J. Woo
Summary: This study aimed to identify different patterns of intrinsic capacity (IC) trajectories in older people and examine their associations with Instrumental Activities of Daily Living (IADL). Three distinct IC trajectories were identified, with the first class being more likely to preserve IADL compared to the second class.
JOURNAL OF NUTRITION HEALTH & AGING
(2023)
Article
Gerontology
Kar Him Mo, Danyang Lei, Jean Woo, Rina Ko
Summary: This study explores the housing preferences of older adults in Hong Kong's private housing estates, finding that safety, thermal comfort, and health-related information become increasingly important as people age. Proximity to facilities, on-site support, and social media were preferred for property information, while home assessment received less attention. The study offers recommendations for improving housing design standards, property management practices, and public education programs for older adults.
JOURNAL OF AGING AND ENVIRONMENT
(2023)
Article
Geriatrics & Gerontology
Ken Cheung, Anson Kai Chun Chau, Jean Woo, Eric T. C. Lai
Summary: This study explored the perceptions of older adults in a highly digitalized city in Hong Kong regarding the impact of the digital age on their daily living during the COVID-19 pandemic. The findings indicated that while ICT provided numerous benefits to the daily life of older adults, they also expressed concerns about age-related losses and the fear of digital exclusion.
ARCHIVES OF GERONTOLOGY AND GERIATRICS
(2023)
Article
Geriatrics & Gerontology
Eric Tsz Chun Lai, Suzanne C. Ho, Jean Woo
Summary: This study investigated the relationship between social isolation, socioeconomic status, and functional impairment. The results showed that older people with lower socioeconomic status, particularly those with lower income, were at a higher risk of social isolation. However, it was unclear whether social isolation mediated the relationship between socioeconomic status and functional impairment.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2023)
