Modified Vaccinia virus Ankara-based vaccines in the era of personalized immunotherapy of cancer

Exome-Scale Discovery of Hotspot Mutation Regions in Human Cancer Using 3D Protein Structure

(2016) Collin Tokheim et al.   CANCER RESEARCH

Immune targets and neoantigens for cancer immunotherapy and precision medicine

(2016) Rong-Fu Wang et al.   CELL RESEARCH

Antigen Targeting to Human HLA Class II Molecules Increases Efficacy of DNA Vaccination

(2016) Gunnveig Grodeland et al.   JOURNAL OF IMMUNOLOGY

TG4010 immunotherapy and first-line chemotherapy for advanced non-small-cell lung cancer (TIME): results from the phase 2b part of a randomised, double-blind, placebo-controlled, phase 2b/3 trial

(2016) Elisabeth Quoix et al.   LANCET ONCOLOGY

Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy

(2016) Lena M. Kranz et al.   NATURE

The cancer vaccine resurgence

(2016) Asher Mullard   NATURE REVIEWS DRUG DISCOVERY

Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma

(2016) Jesse M. Zaretsky et al.   NEW ENGLAND JOURNAL OF MEDICINE

Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry

(2016) Michal Bassani-Sternberg et al.   Nature Communications

Evolution of Neoantigen Landscape during Immune Checkpoint Blockade in Non–Small Cell Lung Cancer

(2016) Valsamo Anagnostou et al.   Cancer Discovery

pVAC-Seq: A genome-guided in silico approach to identifying tumor neoantigens

(2016) Jasreet Hundal et al.   Genome Medicine

Current tools for predicting cancer-specific T cell immunity

(2016) David Gfeller et al.   OncoImmunology

Oncolytic Viruses: Therapeutics With an Identity Crisis

(2016) Caroline J. Breitbach et al.   EBioMedicine

Development of PROSTVAC immunotherapy in prostate cancer

(2015) Parminder Singh et al.   Future Oncology

Tumor neoantigens: building a framework for personalized cancer immunotherapy

(2015) Matthew M. Gubin et al.   JOURNAL OF CLINICAL INVESTIGATION

Mutant MHC class II epitopes drive therapeutic immune responses to cancer

(2015) Sebastian Kreiter et al.   NATURE

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity

(2015) Matthew T Chang et al.   NATURE BIOTECHNOLOGY

Final report of the phase I/II clinical trial of the E75 (nelipepimut-S) vaccine with booster inoculations to prevent disease recurrence in high-risk breast cancer patients

(2014) E. A. Mittendorf et al.   ANNALS OF ONCOLOGY

Wilms Tumor Gene (WT1) Peptide–based Cancer Vaccine Combined With Gemcitabine for Patients With Advanced Pancreatic Cancer

(2014) Sumiyuki Nishida et al.   JOURNAL OF IMMUNOTHERAPY

A phase II trial evaluating the clinical and immunologic response of HLA-A2+ non-small cell lung cancer patients vaccinated with an hTERT cryptic peptide

(2014) Athanasios Kotsakis et al.   LUNG CANCER

Tumor antigenicity revealed

(2014) Peter A. Savage   TRENDS IN IMMUNOLOGY

Antigen-specific vaccines for cancer treatment

(2014) Maria Tagliamonte et al.   Human Vaccines & Immunotherapeutics

Overcoming immunosuppression to enhance a p53MVA vaccine

(2014) Nicola Hardwick et al.   OncoImmunology

Live-attenuated bacteria as a cancer vaccine vector

(2013) Bertrand Toussaint et al.   Expert Review of Vaccines

Oncology Meets Immunology: The Cancer-Immunity Cycle

(2013) Daniel S. Chen et al.   IMMUNITY

Mutational heterogeneity in cancer and the search for new cancer-associated genes

(2013) Michael S. Lawrence et al.   NATURE

DNA Vaccine Delivered by a Needle-Free Injection Device Improves Potency of Priming for Antibody and CD8+ T-Cell Responses after rAd5 Boost in a Randomized Clinical Trial

(2013) Barney S. Graham et al.   PLoS One

Allogeneic dendritic cell (DC) vaccination as an “off the shelf” treatment to prevent or delay relapse in elderly acute myeloid leukemia patients: results of Phase I/IIa safety and feasibility study

(2013) Tanja de Gruijl et al.   Journal for ImmunoTherapy of Cancer

Exploiting the Mutanome for Tumor Vaccination

(2012) J. C. Castle et al.   CANCER RESEARCH

Regression of high-grade cervical intraepithelial neoplasia with TG4001 targeted immunotherapy

(2011) Jean-Luc Brun et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Viral Vector-Based Therapeutic Cancer Vaccines

(2011) Cecilia Larocca et al.   CANCER JOURNAL

Translating Tumor Antigens into Cancer Vaccines

(2010) Luigi Buonaguro et al.   Clinical and Vaccine Immunology

The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research

(2009) M. A. Cheever et al.   CLINICAL CANCER RESEARCH

Heterologous prime–boost vaccination

(2009) Shan Lu   CURRENT OPINION IN IMMUNOLOGY

Clinical development of MVA-based therapeutic cancer vaccines

(2008) Bruce Acres et al.   Expert Review of Vaccines

Differential CD4+ versus CD8+ T-Cell Responses Elicited by Different Poxvirus-Based Human Immunodeficiency Virus Type 1 Vaccine Candidates Provide Comparable Efficacies in Primates

(2008) P. Mooij et al.   JOURNAL OF VIROLOGY

Plasmid DNA- and messenger RNA-based anti-cancer vaccination

(2007) Benjamin Weide et al.   IMMUNOLOGY LETTERS