标题
Intrahepatic cholangiocarcinoma: current management and emerging therapies
作者
关键词
-
出版物
Expert Review of Gastroenterology & Hepatology
Volume 11, Issue 5, Pages 439-449
出版商
Informa UK Limited
发表日期
2017-03-20
DOI
10.1080/17474124.2017.1309290
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- A Multicenter Phase II Study of Gemcitabine, Capecitabine, and Bevacizumab for Locally Advanced or Metastatic Biliary Tract Cancer
- (2018) Renuka V. Iyer et al. AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
- Rare Incidence of ROS1 Rearrangement in Cholangiocarcinoma
- (2017) Sun Min Lim et al. Cancer Research and Treatment
- Comparison of gemcitabine plus cisplatin versus capecitabine plus cisplatin as first-line chemotherapy for advanced biliary tract cancer
- (2016) Kwonoh Park et al. Asia-Pacific Journal of Clinical Oncology
- A phase 1b study of Selumetinib in combination with Cisplatin and Gemcitabine in advanced or metastatic biliary tract cancer: the ABC-04 study
- (2016) John Bridgewater et al. BMC CANCER
- Treatment Selection and Survival Outcomes With and Without Radiation for Unresectable, Localized Intrahepatic Cholangiocarcinoma
- (2016) Matthew W. Jackson et al. CANCER JOURNAL
- Liver transplantation for “very early” intrahepatic cholangiocarcinoma: International retrospective study supporting a prospective assessment
- (2016) G. Sapisochin et al. HEPATOLOGY
- Randomized Phase III study of gemcitabine plus S-1 versus gemcitabine plus cisplatin in advanced biliary tract cancer: Japan Clinical Oncology Group Study (JCOG1113, FUGA-BT)
- (2016) Junki Mizusawa et al. JAPANESE JOURNAL OF CLINICAL ONCOLOGY
- A Hippo and Fibroblast Growth Factor Receptor Autocrine Pathway in Cholangiocarcinoma
- (2016) Sumera Rizvi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeting c-MET by LY2801653 for treatment of cholangiocarcinoma
- (2016) Samarpita Barat et al. MOLECULAR CARCINOGENESIS
- Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA)
- (2016) Jesus M. Banales et al. Nature Reviews Gastroenterology & Hepatology
- Gemcitabine, capecitabine and oxaliplatin with or without cetuximab in advanced biliary tract carcinoma
- (2015) Finn Ole Larsen et al. ACTA ONCOLOGICA
- A KRAS mutation status-stratified randomized phase II trial of gemcitabine and oxaliplatin alone or in combination with cetuximab in advanced biliary tract cancer
- (2015) J. S. Chen et al. ANNALS OF ONCOLOGY
- Panitumumab in combination with gemcitabine and oxaliplatin does not prolong survival in wild-typeKRASadvanced biliary tract cancer: A randomized phase 2 trial (Vecti-BIL study)
- (2015) Francesco Leone et al. CANCER
- Molecular Pathogenesis and Targeted Therapies for Intrahepatic Cholangiocarcinoma
- (2015) A. Moeini et al. CLINICAL CANCER RESEARCH
- Direct Attack on RAS: Intramolecular Communication and Mutation-Specific Effects
- (2015) K. Marcus et al. CLINICAL CANCER RESEARCH
- A phase I trial of mFOLFOX6 combined with the oral PI3K inhibitor BKM120 in patients with advanced refractory solid tumors
- (2015) Autumn J. McRee et al. INVESTIGATIONAL NEW DRUGS
- Cediranib or placebo in combination with cisplatin and gemcitabine chemotherapy for patients with advanced biliary tract cancer (ABC-03): a randomised phase 2 trial
- (2015) Juan W Valle et al. LANCET ONCOLOGY
- Genomic spectra of biliary tract cancer
- (2015) Hiromi Nakamura et al. NATURE GENETICS
- Vemurafenib in Multiple Nonmelanoma Cancers with BRAF V600 Mutations
- (2015) David M. Hyman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Intrahepatic Cholangiocarcinoma: expert consensus statement
- (2015) Sharon M. Weber et al. HPB
- Outcomes following resection of intrahepatic cholangiocarcinoma
- (2015) Parissa Tabrizian et al. HPB
- Stereotactic Body Radiotherapy (SBRT) for Intrahepatic and Hilar Cholangiocarcinoma
- (2015) Anand Mahadevan et al. Journal of Cancer
- The Global Burden of Cancer 2013
- (2015) Christina Fitzmaurice et al. JAMA Oncology
- Immunotherapeutic approaches in biliary tract carcinoma: Current status and emerging strategies
- (2015) Eric I Marks World Journal of Gastrointestinal Oncology
- Antitumor activity of the combination of an HSP90 inhibitor and a PI3K/mTOR dual inhibitor against cholangiocarcinoma
- (2015) Ming-Huang Chen et al. Oncotarget
- A phase I dose escalation study of oral c-MET inhibitor tivantinib (ARQ 197) in combination with gemcitabine in patients with solid tumors
- (2014) S. Pant et al. ANNALS OF ONCOLOGY
- A randomized, multicenter, phase II study of vandetanib monotherapy versus vandetanib in combination with gemcitabine versus gemcitabine plus placebo in subjects with advanced biliary tract cancer: the VanGogh study
- (2014) A. Santoro et al. ANNALS OF ONCOLOGY
- Early Survival and Safety of ALPPS
- (2014) Erik Schadde et al. ANNALS OF SURGERY
- Efficacy and safety of olokizumab in patients with rheumatoid arthritis with an inadequate response to TNF inhibitor therapy: outcomes of a randomised Phase IIb study
- (2014) Mark C Genovese et al. ANNALS OF THE RHEUMATIC DISEASES
- S0941: a phase 2 SWOG study of sorafenib and erlotinib in patients with advanced gallbladder carcinoma or cholangiocarcinoma
- (2014) A B El-Khoueiry et al. BRITISH JOURNAL OF CANCER
- Gemcitabine plus sorafenib versus gemcitabine alone in advanced biliary tract cancer: A double-blind placebo-controlled multicentre phase II AIO study with biomarker and serum programme
- (2014) M. Moehler et al. EUROPEAN JOURNAL OF CANCER
- Dual Inhibition of PI3K-AKT-mTOR- and RAF-MEK-ERK-signaling is synergistic in cholangiocarcinoma and reverses acquired resistance to MEK-inhibitors
- (2014) Florian Ewald et al. INVESTIGATIONAL NEW DRUGS
- Phase I trial of everolimus, gemcitabine and cisplatin in patients with solid tumors
- (2014) Brian A. Costello et al. INVESTIGATIONAL NEW DRUGS
- Molecular pathogenesis of intrahepatic cholangiocarcinoma
- (2014) Jesper B. Andersen Journal of Hepato-Biliary-Pancreatic Sciences
- Guidelines for the diagnosis and management of intrahepatic cholangiocarcinoma
- (2014) John Bridgewater et al. JOURNAL OF HEPATOLOGY
- Comparative effectiveness of hepatic artery based therapies for unresectable intrahepatic cholangiocarcinoma
- (2014) Lucas M. Boehm et al. JOURNAL OF SURGICAL ONCOLOGY
- Cholangiocarcinoma
- (2014) Nataliya Razumilava et al. LANCET
- Gemcitabine and oxaliplatin with or without cetuximab in advanced biliary-tract cancer (BINGO): a randomised, open-label, non-comparative phase 2 trial
- (2014) David Malka et al. LANCET ONCOLOGY
- Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
- (2014) Roy S. Herbst et al. NATURE
- First-Line Crizotinib versus Chemotherapy in ALK-Positive Lung Cancer
- (2014) Benjamin J. Solomon et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cancer Immunotherapy Based on Mutation-Specific CD4+ T Cells in a Patient with Epithelial Cancer
- (2014) E. Tran et al. SCIENCE
- Cholangiocarcinoma: Molecular Pathways and Therapeutic Opportunities
- (2014) Sumera Rizvi et al. SEMINARS IN LIVER DISEASE
- Integrated Genomic Characterization Reveals Novel, Therapeutically Relevant Drug Targets in FGFR and EGFR Pathways in Sporadic Intrahepatic Cholangiocarcinoma
- (2014) Mitesh J. Borad et al. PLoS Genetics
- A Nomogram to Predict Long-term Survival After Resection for Intrahepatic Cholangiocarcinoma
- (2014) Omar Hyder et al. JAMA Surgery
- Treatment and Prognosis for Patients With Intrahepatic Cholangiocarcinoma
- (2014) Michael N. Mavros et al. JAMA Surgery
- Intra-arterial Therapy for Advanced Intrahepatic Cholangiocarcinoma: A Multi-institutional Analysis
- (2013) Omar Hyder et al. ANNALS OF SURGICAL ONCOLOGY
- A phase II study of gemcitabine and cisplatin plus sorafenib in patients with advanced biliary adenocarcinomas
- (2013) J K Lee et al. BRITISH JOURNAL OF CANCER
- Identification ofROS1rearrangement in gastric adenocarcinoma
- (2013) Jeeyun Lee et al. CANCER
- A Critical Role for Notch Signaling in the Formation of Cholangiocellular Carcinomas
- (2013) Steffen Zender et al. CANCER CELL
- Molecular Pathways: JAK/STAT Pathway: Mutations, Inhibitors, and Resistance
- (2013) A. Quintas-Cardama et al. CLINICAL CANCER RESEARCH
- Integrative Molecular Analysis of Intrahepatic Cholangiocarcinoma Reveals 2 Classes That Have Different Outcomes
- (2013) Daniela Sia et al. GASTROENTEROLOGY
- Combined targeting of AKT and mTOR using MK-2206 and RAD001 is synergistic in the treatment of cholangiocarcinoma
- (2013) Florian Ewald et al. INTERNATIONAL JOURNAL OF CANCER
- Prognostic Nomogram for Intrahepatic Cholangiocarcinoma After Partial Hepatectomy
- (2013) Yizhou Wang et al. JOURNAL OF CLINICAL ONCOLOGY
- Sweet syndrome following vemurafenib therapy for recurrent cholangiocarcinoma
- (2013) Penvadee Pattanaprichakul et al. JOURNAL OF CUTANEOUS PATHOLOGY
- ROS1 and ALK Fusions in Colorectal Cancer, with Evidence of Intratumoral Heterogeneity for Molecular Drivers
- (2013) Dara L. Aisner et al. MOLECULAR CANCER RESEARCH
- Intrahepatic cholangiocarcinoma: pathogenesis and rationale for molecular therapies
- (2013) D Sia et al. ONCOGENE
- Mouse model of intrahepatic cholangiocarcinoma validates FIG-ROS as a potent fusion oncogene and therapeutic target
- (2013) A. Saborowski et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Foretinib is a potent inhibitor of oncogenic ROS1 fusion proteins
- (2013) M. A. Davare et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Inhibitor of Mutant IDH1 Delays Growth and Promotes Differentiation of Glioma Cells
- (2013) D. Rohle et al. SCIENCE
- Targeted Inhibition of Mutant IDH2 in Leukemia Cells Induces Cellular Differentiation
- (2013) F. Wang et al. SCIENCE
- Recurrence after operative management of intrahepatic cholangiocarcinoma
- (2013) Omar Hyder et al. SURGERY
- Playing Play-Doh to Prevent Postoperative Liver Failure
- (2012) Eduardo de Santibañes et al. ANNALS OF SURGERY
- Surgical Approach for Long-term Survival of Patients With Intrahepatic Cholangiocarcinoma
- (2012) Dario Ribero ARCHIVES OF SURGERY
- Yttrium-90 Radioembolization for Unresectable Standard-chemorefractory Intrahepatic Cholangiocarcinoma: Survival, Efficacy, and Safety Study
- (2012) Shoaib Rafi et al. CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY
- Genomic Landscape of Non-Small Cell Lung Cancer in Smokers and Never-Smokers
- (2012) Ramaswamy Govindan et al. CELL
- ROS1 as a ‘druggable’ receptor tyrosine kinase: lessons learned from inhibiting the ALK pathway
- (2012) Sai-Hong Ignatius Ou et al. Expert Review of Anticancer Therapy
- Isocitrate dehydrogenase 1 and 2 mutations in cholangiocarcinoma
- (2012) Benjamin R. Kipp et al. HUMAN PATHOLOGY
- Adjuvant Therapy in the Treatment of Biliary Tract Cancer: A Systematic Review and Meta-Analysis
- (2012) Anne M. Horgan et al. JOURNAL OF CLINICAL ONCOLOGY
- Targeting the Interleukin-6/Jak/Stat Pathway in Human Malignancies
- (2012) Pasquale Sansone et al. JOURNAL OF CLINICAL ONCOLOGY
- Radiofrequency Ablation in the Management of Unresectable Intrahepatic Cholangiocarcinoma
- (2012) Ying Fu et al. JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
- Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas
- (2012) P Wang et al. ONCOGENE
- HER2/neu May Not Be an Interesting Target in Biliary Cancers: Results of an Early Phase II Study with Lapatinib
- (2012) Joshua Peck et al. ONCOLOGY
- Prognostic significance of overexpression of c-Met oncoprotein in cholangiocarcinoma
- (2011) M Miyamoto et al. BRITISH JOURNAL OF CANCER
- Stereotactic Radiofrequency Ablation of Unresectable Intrahepatic Cholangiocarcinomas: A Retrospective Study
- (2011) Marion Haidu et al. CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY
- IL-6 signaling in autoimmunity, chronic inflammation and inflammation-associated cancer
- (2011) Markus F. Neurath et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Inhibition of Ras for cancer treatment: the search continues
- (2011) Antonio T Baines et al. Future Medicinal Chemistry
- Myofibroblast-derived PDGF-BB promotes hedgehog survival signaling in cholangiocarcinoma cells
- (2011) Christian D. Fingas et al. HEPATOLOGY
- SWOG 0514: a phase II study of sorafenib in patients with unresectable or metastatic gallbladder carcinoma and cholangiocarcinoma
- (2011) Anthony B. El-Khoueiry et al. INVESTIGATIONAL NEW DRUGS
- Multi-Institutional Phase II Study of Selumetinib in Patients With Metastatic Biliary Cancers
- (2011) Tanios Bekaii-Saab et al. JOURNAL OF CLINICAL ONCOLOGY
- Intrahepatic Cholangiocarcinoma: An International Multi-Institutional Analysis of Prognostic Factors and Lymph Node Assessment
- (2011) Mechteld C. de Jong et al. JOURNAL OF CLINICAL ONCOLOGY
- Potent in vitro and in vivo antitumor activity of sorafenib against human intrahepatic cholangiocarcinoma cells
- (2011) Hiroaki Sugiyama et al. JOURNAL OF GASTROENTEROLOGY
- Gemcitabine and oxaliplatin with or without erlotinib in advanced biliary-tract cancer: a multicentre, open-label, randomised, phase 3 study
- (2011) Jeeyun Lee et al. LANCET ONCOLOGY
- Survey of Tyrosine Kinase Signaling Reveals ROS Kinase Fusions in Human Cholangiocarcinoma
- (2011) Ting-Lei Gu et al. PLoS One
- The American Joint Committee on Cancer: the 7th Edition of the AJCC Cancer Staging Manual and the Future of TNM
- (2010) Stephen B. Edge et al. ANNALS OF SURGICAL ONCOLOGY
- KRAS and PIK3CA but not BRAF genes are frequently mutated in Chinese cholangiocarcinoma patients
- (2010) Rui Feng Xu et al. BIOMEDICINE & PHARMACOTHERAPY
- Determining the role of external beam radiotherapy in unresectable intrahepatic cholangiocarcinoma: a retrospective analysis of 84 patients
- (2010) Yi-Xing Chen et al. BMC CANCER
- Gemcitabine alone or in combination with cisplatin in patients with biliary tract cancer: a comparative multicentre study in Japan
- (2010) T Okusaka et al. BRITISH JOURNAL OF CANCER
- Monoclonal Antibodies to Fibroblast Growth Factor Receptor 2 Effectively Inhibit Growth of Gastric Tumor Xenografts
- (2010) W.-m. Zhao et al. CLINICAL CANCER RESEARCH
- Preclinical assessment of simultaneous targeting of epidermal growth factor receptor (ErbB1) and ErbB2 as a strategy for cholangiocarcinoma therapy
- (2010) Zichen Zhang et al. HEPATOLOGY
- Regorafenib (BAY 73-4506): A new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity
- (2010) Scott M. Wilhelm et al. INTERNATIONAL JOURNAL OF CANCER
- Phase II study of second line gemcitabine single chemotherapy for biliary tract cancer patients with 5-fluorouracil refractoriness
- (2010) Sung Yong Oh et al. INVESTIGATIONAL NEW DRUGS
- Best Supportive Care Compared With Chemotherapy for Unresectable Gall Bladder Cancer: A Randomized Controlled Study
- (2010) Atul Sharma et al. JOURNAL OF CLINICAL ONCOLOGY
- Report of a Multicenter Phase II Trial Testing a Combination of Biweekly Bevacizumab and Daily Erlotinib in Patients With Unresectable Biliary Cancer: A Phase II Consortium Study
- (2010) Sam J. Lubner et al. JOURNAL OF CLINICAL ONCOLOGY
- Portal vein embolization (prior to major hepatectomy) effects on regeneration, resectability, and outcome
- (2010) Eddie K. Abdalla JOURNAL OF SURGICAL ONCOLOGY
- Cetuximab, gemcitabine, and oxaliplatin in patients with unresectable advanced or metastatic biliary tract cancer: a phase 2 study
- (2010) Birgit Gruenberger et al. LANCET ONCOLOGY
- Cisplatin plus Gemcitabine versus Gemcitabine for Biliary Tract Cancer
- (2010) Juan Valle et al. NEW ENGLAND JOURNAL OF MEDICINE
- Second-Line Treatment With a Combination of Continuous 5-Fluorouracil, Doxorubicin, and Mitomycin-C (Conti-Fam) in Gemcitabine-Pretreated Pancreatic and Biliary Tract Cancer
- (2009) Suee Lee et al. AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
- Intrahepatic Cholangiocarcinoma
- (2009) Itaru Endo et al. ANNALS OF SURGERY
- Sorafenib in patients with advanced biliary tract carcinoma: a phase II trial
- (2009) C Bengala et al. BRITISH JOURNAL OF CANCER
- The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors
- (2009) Michael Hedvat et al. CANCER CELL
- Efficacy and safety of gemcitabine, oxaliplatin, and bevacizumab in advanced biliary-tract cancers and correlation of changes in 18-fluorodeoxyglucose PET with clinical outcome: a phase 2 study
- (2009) Andrew X Zhu et al. LANCET ONCOLOGY
- Transcatheter arterial chemoembolization or chemoinfusion for unresectable intrahepatic cholangiocarcinoma
- (2008) Jin Hyoung Kim et al. CANCER
- Evidence-Based Approach to Cholangiocarcinoma: A Systematic Review of the Current Literature
- (2008) Murad Aljiffry et al. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
- Role of ErbB family receptor tyrosine kinases in intrahepatic cholangiocarcinoma
- (2008) Alphonse E Sirica WORLD JOURNAL OF GASTROENTEROLOGY
- Standardized Liver Volumetry for Portal Vein Embolization
- (2008) Dario Ribero et al. SEMINARS IN INTERVENTIONAL RADIOLOGY
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