Myofibroblast-derived PDGF-BB promotes hedgehog survival signaling in cholangiocarcinoma cells

Hedgehog-Producing Cancer Cells Respond to and Require Autocrine Hedgehog Activity

(2011) S. Singh et al.   CANCER RESEARCH

Hedgehog signaling and gastrointestinal cancer

(2010) Milena Saqui-Salces et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner

(2010) Neta Erez et al.   CANCER CELL

Receptor Tyrosine Kinase Coactivation Networks in Cancer

(2010) A. M. Xu et al.   CANCER RESEARCH

Hedgehog Signaling Uses Lipid Metabolism to Tune Smoothened Activation

(2010) Yongfei Yang et al.   DEVELOPMENTAL CELL

Role of Lipid Metabolism in Smoothened Derepression in Hedgehog Signaling

(2010) Amir Yavari et al.   DEVELOPMENTAL CELL

Activation of fibroblasts in cancer stroma

(2010) Kati Räsänen et al.   EXPERIMENTAL CELL RESEARCH

A smac mimetic reduces TNF Related Apoptosis Inducing Ligand (TRAIL)-induced invasion and metastasis of cholangiocarcinoma cells

(2010) Christian D. Fingas et al.   HEPATOLOGY

GLI3-dependent repression of DR4 mediates hedgehog antagonism of TRAIL-induced apoptosis

(2010) S Kurita et al.   ONCOGENE

Not Lost in Space: Trafficking in the Hedgehog Signaling Pathway

(2010) L. Milenkovic et al.   Science Signaling

Prognostic Assessment of Three Single-Nucleotide Polymorphisms (GNB3825C>T,BCL2-938C>A,MCL1-386C>G) in Extrahepatic Cholangiocarcinoma

(2009) Christian Dominik Fingas et al.   CANCER INVESTIGATION

Sorafenib inhibits signal transducer and activator of transcription-3 signaling in cholangiocarcinoma cells by activating the phosphatase shatterproof 2

(2009) Boris R. A. Blechacz et al.   HEPATOLOGY

Portal fibroblasts: Underappreciated mediators of biliary fibrosis

(2009) Jonathan A. Dranoff et al.   HEPATOLOGY

Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade

(2009) J. M. Hyman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

(2009) K. P. Olive et al.   SCIENCE

cAMP-dependent protein kinase A and the dynamics of epithelial cell surface domains: Moving membranes to keep in shape

(2008) Kacper A. Wojtal et al.   BIOESSAYS

Role of platelet-derived growth factors in physiology and medicine

(2008) J. Andrae et al.   GENES & DEVELOPMENT

The hedgehog pathway regulates remodelling responses to biliary obstruction in rats

(2008) A Omenetti et al.   GUT

Cholangiocarcinoma: Advances in pathogenesis, diagnosis, and treatment

(2008) Boris Blechacz et al.   HEPATOLOGY

Protein Kinase A Regulates 3-Phosphatidylinositide Dynamics during Platelet-derived Growth Factor-induced Membrane Ruffling and Chemotaxis

(2008) Paula B. Deming et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A paracrine requirement for hedgehog signalling in cancer

(2008) Robert L. Yauch et al.   NATURE

Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver

(2008) Scott L. Friedman   PHYSIOLOGICAL REVIEWS