CRISPR Transcriptional Activation Analysis Unmasks an Occult γ-Secretase Processivity Defect in Familial Alzheimer’s Disease Skin Fibroblasts

出版年份 2017 全文链接

标题

作者

关键词

CRISPR/Cas9, synergistic activation mediator, Alzheimer’s disease, amyloid precursor protein, β-amyloid, BACE1, presenilin, fibroblast, induced neuronal cells, γ-secretase processivity

出版物

Cell Reports

Volume 21, Issue 7, Pages 1727-1736

出版商

Elsevier BV

发表日期

2017-11-15

DOI

10.1016/j.celrep.2017.10.075

向作者/读者发起求助以获取更多资源

Protocol

在线求助

Reagent

在线求助

Reprint

联系作者

Discover Peeref hubs

Discuss science. Find collaborators. Network.

Join a conversation

Add your recorded webinar

Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.

Upload Now