CAR T Cells Releasing IL-18 Convert to T-Bet high FoxO1 low Effectors that Exhibit Augmented Activity against Advanced Solid Tumors

标题
CAR T Cells Releasing IL-18 Convert to T-Bet high FoxO1 low Effectors that Exhibit Augmented Activity against Advanced Solid Tumors
作者
关键词
chimeric antigen receptor, CAR, adoptive cell therapy, pancreatic carcinoma, carcinoembryonic antigen, CEA, IL-12, IL-18, TRUCK
出版物
Cell Reports
Volume 21, Issue 11, Pages 3205-3219
出版商
Elsevier BV
发表日期
2017-12-13
DOI
10.1016/j.celrep.2017.11.063

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