Understanding the cholesterol metabolism-perturbing effects of docosahexaenoic acid by gas chromatography–mass spectrometry targeted metabonomic profiling

Metabotyping of Docosahexaenoic Acid - Treated Alzheimer’s Disease Cell Model

(2014) Priti Bahety et al.   PLoS One

Specific antibody binding to the APP672–699 region shifts APP processing from α- to β-cleavage

(2014) S Li et al.   Cell Death & Disease

Polyunsaturated fatty acyl-coenzyme As are inhibitors of cholesterol biosynthesis in zebrafish and mice

(2013) S. Karanth et al.   Disease Models & Mechanisms

Suppression of amyloid-β production by 24S-hydroxycholesterol via inhibition of intracellular amyloid precursor protein trafficking

(2013) Yasuomi Urano et al.   FASEB JOURNAL

Metabolism of oxysterols derived from nonenzymatic oxidation of 7-dehydrocholesterol in cells

(2013) Libin Xu et al.   JOURNAL OF LIPID RESEARCH

Omega 3 fatty acids chemosensitize multidrug resistant colon cancer cells by down-regulating cholesterol synthesis and altering detergent resistant membranes composition

(2013) Giada Gelsomino et al.   Molecular Cancer

Comparing metabolomic and pathologic biomarkers alone and in combination for discriminating Alzheimer’s disease from normal cognitive aging

(2013) Alison A Motsinger-Reif et al.   Acta Neuropathologica Communications

Alzheimer’s Disease, Cholesterol, and Statins: The Junctions of Important Metabolic Pathways

(2012) Tiago Silva et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Amyloid Precursor Protein Has a Flexible Transmembrane Domain and Binds Cholesterol

(2012) P. J. Barrett et al.   SCIENCE

Docosahexaenoic Acid Signalolipidomics in Nutrition: Significance in Aging, Neuroinflammation, Macular Degeneration, Alzheimer's, and Other Neurodegenerative Diseases

(2011) Nicolas G. Bazan et al.   Annual Review of Nutrition

Docosahexaenoic Acid Reduces Amyloid β Production via Multiple Pleiotropic Mechanisms

(2011) Marcus O. W. Grimm et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of eicosapentaenoic acid and docosahexaenoic acid on low-density lipoprotein cholesterol and other lipids: A review

(2011) Terry A. Jacobson et al.   Journal of Clinical Lipidology

Marked accumulation of 27-hydroxycholesterol in the brains of Alzheimer's patients with the Swedish APP 670/671 mutation

(2011) Marjan Shafaati et al.   JOURNAL OF LIPID RESEARCH

Metabolome in progression to Alzheimer's disease

(2011) M Orešič et al.   Translational Psychiatry

Isoprenoids, small GTPases and Alzheimer's disease

(2010) Gero P. Hooff et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Plasma metabolic profiling of Alzheimer's disease by liquid chromatography/mass spectrometry

(2010) Nai-jing Li et al.   CLINICAL BIOCHEMISTRY

Fatty acid transport across the cell membrane: Regulation by fatty acid transporters

(2010) Robert W. Schwenk et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

A proposed metabolic strategy for monitoring disease progression in Alzheimer's disease

(2009) Nicola Greenberg et al.   ELECTROPHORESIS

Inhibition of acyl-coenzyme A: cholesterol acyl transferase modulates amyloid precursor protein trafficking in the early secretory pathway

(2009) Henri J. Huttunen et al.   FASEB JOURNAL

Combined gas chromatographic/mass spectrometric analysis of cholesterol precursors and plant sterols in cultured cells

(2009) Jure Acimovic et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on β-amyloid precursor protein levels and processing in human neuroblastoma SH-SY5Y cells

(2009) Jaya RP Prasanthi et al.   Molecular Neurodegeneration

Docosahexaenoic acid (DHA) and cardiovascular disease risk factors

(2009) Bruce J. Holub   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

A TAG1-APP signalling pathway through Fe65 negatively modulates neurogenesis

(2008) Quan-Hong Ma et al.   NATURE CELL BIOLOGY