The Hcp proteins fused with diverse extended-toxin domains represent a novel pattern of antibacterial effectors in type VI secretion systems

Strain competition restricts colonization of an enteric pathogen and prevents colitis

(2016) Aaron L Hecht et al.   EMBO REPORTS

Interplay of regulatory RNAs and mobile genetic elements in enteric pathogens

(2016) Kathrin S. Fröhlich et al.   MOLECULAR MICROBIOLOGY

SalmonellaTyphimurium utilizes a T6SS-mediated antibacterial weapon to establish in the host gut

(2016) Thibault G. Sana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Pseudomonas aeruginosa Type VI Secretion PGAP1-like Effector Induces Host Autophagy by Activating Endoplasmic Reticulum Stress

(2016) Feng Jiang et al.   Cell Reports

An Interbacterial NAD(P)+ Glycohydrolase Toxin Requires Elongation Factor Tu for Delivery to Target Cells

(2015) John C. Whitney et al.   CELL

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

Secretion systems in Gram-negative bacteria: structural and mechanistic insights

(2015) Tiago R. D. Costa et al.   NATURE REVIEWS MICROBIOLOGY

Identification of divergent type VI secretion effectors using a conserved chaperone domain

(2015) Xiaoye Liang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kin cell lysis is a danger signal that activates antibacterial pathways of Pseudomonas aeruginosa

(2015) Michele LeRoux et al.   eLife

A Pseudomonas aeruginosa Type VI Secretion Phospholipase D Effector Targets Both Prokaryotic and Eukaryotic Cells

(2014) Feng Jiang et al.   Cell Host & Microbe

A Type VI Secretion-Related Pathway in Bacteroidetes Mediates Interbacterial Antagonism

(2014) Alistair B. Russell et al.   Cell Host & Microbe

Agrobacterium tumefaciens Deploys a Superfamily of Type VI Secretion DNase Effectors as Weapons for Interbacterial Competition In Planta

(2014) Lay-Sun Ma et al.   Cell Host & Microbe

Type VI secretion and bacteriophage tail tubes share a common assembly pathway

(2014) Y. R. Brunet et al.   EMBO REPORTS

Two Functional Type VI Secretion Systems in Avian Pathogenic Escherichia coli Are Involved in Different Pathogenic Pathways

(2014) Jiale Ma et al.   INFECTION AND IMMUNITY

VgrG-5 Is a Burkholderia Type VI Secretion System-Exported Protein Required for Multinucleated Giant Cell Formation and Virulence

(2014) Sandra Schwarz et al.   INFECTION AND IMMUNITY

Type VI secretion system effectors: poisons with a purpose

(2014) Alistair B. Russell et al.   NATURE REVIEWS MICROBIOLOGY

Crystal Structure and Self-Interaction of the Type VI Secretion Tail-Tube Protein from Enteroaggregative Escherichia coli

(2014) Badreddine Douzi et al.   PLoS One

Marker for type VI secretion system effectors

(2014) D. Salomon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Vibrio cholerae type VI secretion system employs diverse effector modules for intraspecific competition

(2014) Daniel Unterweger et al.   Nature Communications

Mechanisms and Biological Roles of Contact-Dependent Growth Inhibition Systems

(2014) C. S. Hayes et al.   Cold Spring Harbor Perspectives in Medicine

Selection of Orphan Rhs Toxin Expression in Evolved Salmonella enterica Serovar Typhimurium

(2014) Sanna Koskiniemi et al.   PLoS Genetics

A View to a Kill: The Bacterial Type VI Secretion System

(2013) Brian T. Ho et al.   Cell Host & Microbe

Genetic diversity and features analysis of type VI secretion systems loci in avian pathogenic Escherichia coli by wide genomic scanning

(2013) Jiale Ma et al.   INFECTION GENETICS AND EVOLUTION

Identification, Structure, and Function of a Novel Type VI Secretion Peptidoglycan Glycoside Hydrolase Effector-Immunity Pair

(2013) John C. Whitney et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lytic Activity of theVibrio choleraeType VI Secretion Toxin VgrG-3 Is Inhibited by the Antitoxin TsaB

(2013) Teresa M. Brooks et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Haemolysin Coregulated Protein Is an Exported Receptor and Chaperone of Type VI Secretion Substrates

(2013) Julie M. Silverman et al.   MOLECULAR CELL

Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors

(2013) Alistair B. Russell et al.   NATURE

PAAR-repeat proteins sharpen and diversify the type VI secretion system spike

(2013) Mikhail M. Shneider et al.   NATURE

Identification of T6SS-dependent effector and immunity proteins by Tn-seq in Vibrio cholerae

(2013) T. G. Dong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rhs proteins from diverse bacteria mediate intercellular competition

(2013) S. Koskiniemi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two Independent Pathways for Self-Recognition in Proteus mirabilis Are Linked by Type VI-Dependent Export

(2013) L. M. Wenren et al.   mBio

Dual Expression Profile of Type VI Secretion System Immunity Genes Protects Pandemic Vibrio cholerae

(2013) Sarah T. Miyata et al.   PLoS Pathogens

Polymorphic toxin systems: Comprehensive characterization of trafficking modes, processing, mechanisms of action, immunity and ecology using comparative genomics

(2012) Dapeng Zhang et al.   Biology Direct

A Widespread Bacterial Type VI Secretion Effector Superfamily Identified Using a Heuristic Approach

(2012) Alistair B. Russell et al.   Cell Host & Microbe

Identification of a target cell permissive factor required for contact-dependent growth inhibition (CDI)

(2012) E. J. Diner et al.   GENES & DEVELOPMENT

Comparative genomics of the type VI secretion systems of Pantoea and Erwinia species reveals the presence of putative effector islands that may be translocated by the VgrG and Hcp proteins

(2011) Pieter De Maayer et al.   BMC GENOMICS

Hcp Family Proteins Secreted via the Type VI Secretion System Coordinately Regulate Escherichia coli K1 Interaction with Human Brain Microvascular Endothelial Cells

(2011) Yan Zhou et al.   INFECTION AND IMMUNITY

Genomic analysis of the type VI secretion systems in Pseudomonas spp.: novel clusters and putative effectors uncovered

(2011) M. Barret et al.   MICROBIOLOGY-SGM

Close encounters: contact-dependent interactions in bacteria

(2011) Anna Konovalova et al.   MOLECULAR MICROBIOLOGY

Type VI secretion delivers bacteriolytic effectors to target cells

(2011) Alistair B. Russell et al.   NATURE

Identification of Functional Toxin/Immunity Genes Linked to Contact-Dependent Growth Inhibition (CDI) and Rearrangement Hotspot (Rhs) Systems

(2011) Stephen J. Poole et al.   PLoS Genetics

Bacterial Contact-Dependent Delivery Systems

(2010) Christopher S. Hayes et al.   Annual Review of Genetics

A Type VI Secretion System of Pseudomonas aeruginosa Targets a Toxin to Bacteria

(2010) Rachel D. Hood et al.   Cell Host & Microbe

A widespread family of polymorphic contact-dependent toxin delivery systems in bacteria

(2010) Stephanie K. Aoki et al.   NATURE

Comparative genomic analysis uncovers 3 novel loci encoding type six secretion systems differentially distributed in Salmonella serotypes

(2009) Carlos J Blondel et al.   BMC GENOMICS

Protein structure prediction on the Web: a case study using the Phyre server

(2009) Lawrence A Kelley et al.   Nature Protocols

The phage   major tail protein structure reveals a common evolution for long-tailed phages and the type VI bacterial secretion system

(2009) L. G. Pell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fitness of Escherichia coli during Urinary Tract Infection Requires Gluconeogenesis and the TCA Cycle

(2009) Christopher J. Alteri et al.   PLoS Pathogens

Mutational and transcriptional analyses of an avian pathogenic Escherichia coli ColV plasmid

(2008) Jerod A Skyberg et al.   BMC MICROBIOLOGY

Type VI secretion: a beginner's guide

(2008) Lewis EH Bingle et al.   CURRENT OPINION IN MICROBIOLOGY

In vitro self-assembly of tailorable nanotubes from a simple protein building block

(2008) E. R. Ballister et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA