P450 monooxygenase ComJ catalyses side chain phenolic cross-coupling during complestatin biosynthesis

Biochemical and structural characterisation of the second oxidative crosslinking step during the biosynthesis of the glycopeptide antibiotic A47934

(2016) Veronika Ulrich et al.   Beilstein Journal of Organic Chemistry

Generation of New Complestatin Analogues by Heterologous Expression of the Complestatin Biosynthetic Gene Cluster fromStreptomyces chartreusisAN1542

(2016) Ok-Kyung Park et al.   CHEMBIOCHEM

Understanding the crucial interactions between Cytochrome P450s and non-ribosomal peptide synthetases during glycopeptide antibiotic biosynthesis

(2016) Madeleine Peschke et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Structure of OxyAtei: completing our picture of the glycopeptide antibiotic producing Cytochrome P450 cascade

(2016) Kristina Haslinger et al.   FEBS LETTERS

Regulation of the P450 Oxygenation Cascade Involved in Glycopeptide Antibiotic Biosynthesis

(2016) Madeleine Peschke et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

More than just recruitment: the X-domain influences catalysis of the first phenolic coupling reaction in A47934 biosynthesis by Cytochrome P450 StaH

(2016) Veronika Ulrich et al.   Molecular BioSystems

F-O-G Ring Formation in Glycopeptide Antibiotic Biosynthesis is Catalysed by OxyE

(2016) Madeleine Peschke et al.   Scientific Reports

Sequential In Vitro Cyclization by Cytochrome P450 Enzymes of Glycopeptide Antibiotic Precursors Bearing the X-Domain from Nonribosomal Peptide Biosynthesis

(2015) Clara Brieke et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Complestatin Exerts Antibacterial Activity by the Inhibition of Fatty Acid Synthesis

(2015) Yun-Ju Kwon et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

X-domain of peptide synthetases recruits oxygenases crucial for glycopeptide biosynthesis

(2015) Kristina Haslinger et al.   NATURE

Cytochrome P450 OxyBteiCatalyzes the First Phenolic Coupling Step in Teicoplanin Biosynthesis

(2014) Kristina Haslinger et al.   CHEMBIOCHEM

A Facile Fmoc Solid Phase Synthesis Strategy To Access Epimerization-Prone Biosynthetic Intermediates of Glycopeptide Antibiotics

(2014) Clara Brieke et al.   ORGANIC LETTERS

Glycopeptide antibiotic biosynthesis

(2013) Grace Yim et al.   JOURNAL OF ANTIBIOTICS

Total Synthesis of Complestatin (Chloropeptin II)

(2010) Zhihui Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structural characterization of CYP165D3, a cytochrome P450 involved in phenolic coupling in teicoplanin biosynthesis

(2010) Max J. Cryle et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Total Synthesis of Complestatin: Development of a Pd(0)-Mediated Indole Annulation for Macrocyclization

(2010) Hiroyuki Shimamura et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phosphopantetheinyl Transferase Catalyzed Site-Specific Protein Labeling with ADP Conjugated Chemical Probes

(2009) Yekui Zou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of Chloropeptin II (Complestatin) and Chloropeptin I

(2009) Joie Garfunkle et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Exploring the substrate specificity of OxyB, a phenol coupling P450 enzyme involved in vancomycin biosynthesis

(2008) Katharina Woithe et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Screening of fusion partners for high yield expression and purification of bioactive viscotoxins

(2008) Julius Bogomolovas et al.   PROTEIN EXPRESSION AND PURIFICATION

New insights into the first oxidative phenol coupling reaction during vancomycin biosynthesis

(2007) Nina Geib et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS