An Exercise‐Only Intervention in Obese Fathers Restores Glucose and Insulin Regulation in Conjunction with the Rescue of Pancreatic Islet Cell Morphology and MicroRNA Expression in Male Offspring

Exercise during pregnancy protects against hypertension and macrosomia: randomized clinical trial

(2016) Ruben Barakat et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Parental pre-pregnancy BMI influences on offspring BMI and waist circumference at 21 years

(2016) Nurzalinda Zalbahar et al.   AUSTRALIAN AND NEW ZEALAND JOURNAL OF PUBLIC HEALTH

tRNA fragments: novel players in intergenerational inheritance

(2016) Katharina Gapp et al.   CELL RESEARCH

Paternal long-term exercise programs offspring for low energy expenditure and increased risk for obesity in mice

(2016) Alexander K. Murashov et al.   FASEB JOURNAL

Inheritance of diet-induced metabolic changes via tsRNAs

(2016) Denise Waldron   NATURE REVIEWS GENETICS

High-fat diet reprograms the epigenome of rat spermatozoa and transgenerationally affects metabolism of the offspring

(2016) Thais de Castro Barbosa et al.   Molecular Metabolism

Male-lineage transmission of an acquired metabolic phenotype induced by grand-paternal obesity

(2016) Jennifer E. Cropley et al.   Molecular Metabolism

Sperm microRNA Content Is Altered in a Mouse Model of Male Obesity, but the Same Suite of microRNAs Are Not Altered in Offspring’s Sperm

(2016) Tod Fullston et al.   PLoS One

Preconception diet or exercise intervention in obese fathers normalizes sperm microRNA profile and metabolic syndrome in female offspring

(2015) Nicole O. McPherson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

MicroRNAs as regulators of metabolic disease: pathophysiologic significance and emerging role as biomarkers and therapeutics

(2015) J A Deiuliis   INTERNATIONAL JOURNAL OF OBESITY

Transgenerational epigenetic programming via sperm microRNA recapitulates effects of paternal stress

(2015) Ali B. Rodgers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder

(2015) Q. Chen et al.   SCIENCE

Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals

(2015) U. Sharma et al.   SCIENCE

Circulating miRNAs as intercellular messengers, potential biomarkers and therapeutic targets for Type 2 diabetes

(2015) Paola Mirra et al.   Epigenomics

RNA-mediated paternal heredity of diet-induced obesity and metabolic disorders

(2015) Valérie Grandjean et al.   Scientific Reports

Paternal high-fat diet consumption induces common changes in the transcriptomes of retroperitoneal adipose and pancreatic islet tissues in female rat offspring

(2014) Sheau-Fang Ng et al.   FASEB JOURNAL

Obese father’s metabolic state, adiposity, and reproductive capacity indicate son’s reproductive health

(2014) Nicole O. McPherson et al.   FERTILITY AND STERILITY

Implication of sperm RNAs in transgenerational inheritance of the effects of early trauma in mice

(2014) Katharina Gapp et al.   NATURE NEUROSCIENCE

Improving basic and translational science by accounting for litter-to-litter variation in animal models

(2013) Stanley E Lazic et al.   BMC NEUROSCIENCE

 -Cell Failure in Type 2 Diabetes: A Case of Asking Too Much of Too Few?

(2013) S. Costes et al.   DIABETES

Developmental Programming by Maternal Insulin Resistance: Hyperinsulinemia, Glucose Intolerance, and Dysregulated Lipid Metabolism in Male Offspring of Insulin-Resistant Mice

(2013) E. Isganaitis et al.   DIABETES

Paternal obesity initiates metabolic disturbances in two generations of mice with incomplete penetrance to the F2 generation and alters the transcriptional profile of testis and sperm microRNA content

(2013) Tod Fullston et al.   FASEB JOURNAL

Changes in circulating microRNAs levels with exercise modality

(2013) Sébastien Banzet et al.   JOURNAL OF APPLIED PHYSIOLOGY

Paternal Stress Exposure Alters Sperm MicroRNA Content and Reprograms Offspring HPA Stress Axis Regulation

(2013) A. B. Rodgers et al.   JOURNAL OF NEUROSCIENCE

Profiling of Circulating MicroRNAs after a Bout of Acute Resistance Exercise in Humans

(2013) Shuji Sawada et al.   PLoS One

Improving Metabolic Health in Obese Male Mice via Diet and Exercise Restores Embryo Development and Fetal Growth

(2013) Nicole O. McPherson et al.   PLoS One

Diet and exercise in an obese mouse fed a high-fat diet improve metabolic health and reverse perturbed sperm function

(2012) Nicole O. Palmer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The risk of maternal obesity to the long-term health of the offspring

(2012) James R. O'Reilly et al.   CLINICAL ENDOCRINOLOGY

Diet-induced paternal obesity in the absence of diabetes diminishes the reproductive health of two subsequent generations of mice

(2012) T. Fullston et al.   HUMAN REPRODUCTION

Prevalence of Obesity and Trends in the Distribution of Body Mass Index Among US Adults, 1999-2010

(2012) Katherine M. Flegal et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Control of glucose homeostasis and insulin sensitivity by the Let-7 family of microRNAs

(2011) R. J. A. Frost et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SIRT6 in mouse spermatogenesis is modulated by diet-induced obesity

(2011) Nicole O. Palmer et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

Paternal diet-induced obesity impairs embryo development and implantation in the mouse

(2010) Megan Mitchell et al.   FERTILITY AND STERILITY

The effect of paternal diet-induced obesity on sperm function and fertilization in a mouse model

(2010) H. W. Bakos et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring

(2010) Sheau-Fang Ng et al.   NATURE

Impaired β-Cell Function and Inadequate Compensatory Increases in β-Cell Mass after Intrauterine Growth Restriction in Sheep

(2008) Kathryn L. Gatford et al.   ENDOCRINOLOGY