Two chaperones locked in an embrace: structure and function of the ribosome-associated complex RAC

Moonlighting chaperone-like activity of the universal regulatory 14-3-3 proteins

(2017) Nikolai N. Sluchanko et al.   FEBS Journal

Structural insights into a unique Hsp70-Hsp40 interaction in the eukaryotic ribosome-associated complex

(2017) Felix Alexander Weyer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural insights into a unique Hsp70-Hsp40 interaction in the eukaryotic ribosome-associated complex

(2017) Felix Alexander Weyer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

On-site remodeling at chromatin: How multiprotein complexes are rebuilt during DNA repair and transcriptional activation

(2016) Thaleia Papadopoulou et al.   BIOESSAYS

The yeast Hsp70 homolog Ssb: a chaperone for general de novo protein folding and a nanny for specific intrinsically disordered protein domains

(2016) Volker Hübscher et al.   CURRENT GENETICS

Dual role of ribosome-associated chaperones in prion formation and propagation

(2016) Yury O. Chernoff et al.   CURRENT GENETICS

ZRF1 mediates remodeling of E3 ligases at DNA lesion sites during nucleotide excision repair

(2016) Ekaterina Gracheva et al.   JOURNAL OF CELL BIOLOGY

Mature proteins braced by a chaperone

(2016) Qinglian Liu et al.   NATURE

Alternative modes of client binding enable functional plasticity of Hsp70

(2016) Alireza Mashaghi et al.   NATURE

Dual interaction of the Hsp70 J-protein cochaperone Zuotin with the 40S and 60S ribosomal subunits

(2016) Kanghyun Lee et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Hsp70 homolog Ssb and the 14-3-3 protein Bmh1 jointly regulate transcription of glucose repressed genes inSaccharomyces cerevisiae

(2016) Volker Hübscher et al.   NUCLEIC ACIDS RESEARCH

Silencing of ZRF1 impedes survival of estrogen receptor positive MCF-7 cells and potentiates the effect of curcumin

(2016) Sandip Kumar Rath et al.   TUMOR BIOLOGY

Multivalent contacts of the Hsp70 Ssb contribute to its architecture on ribosomes and nascent chain interaction

(2016) Marie A. Hanebuth et al.   Nature Communications

Interaction of the cotranslational Hsp70 Ssb with ribosomal proteins and rRNA depends on its lid domain

(2016) Andrea Gumiero et al.   Nature Communications

Dual interaction of the Hsp70 J-protein cochaperone Zuotin with the 40S and 60S ribosomal subunits

(2016) Kanghyun Lee et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A conserved domain important for association of eukaryotic J-protein co-chaperones Jjj1 and Zuo1 with the ribosome

(2015) Lindsey A. Kaschner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Feedback control of prion formation and propagation by the ribosome-associated chaperone complex

(2015) Denis A. Kiktev et al.   MOLECULAR MICROBIOLOGY

Pathways of allosteric regulation in Hsp70 chaperones

(2015) Roman Kityk et al.   Nature Communications

Direct interaction between Id1 and Zrf1 controls neural differentiation of embryonic stem cells

(2014) L. Aloia et al.   EMBO REPORTS

Hierarchical Functional Specificity of Cytosolic Heat Shock Protein 70 (Hsp70) Nucleotide Exchange Factors in Yeast

(2014) Jennifer L. Abrams et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Release Factor eRF3 Mediates Premature Translation Termination on Polylysine-Stalled Ribosomes in Saccharomyces cerevisiae

(2014) M. Chiabudini et al.   MOLECULAR AND CELLULAR BIOLOGY

Structural basis for the inhibition of the eukaryotic ribosome

(2014) Nicolas Garreau de Loubresse et al.   NATURE

Structural basis for interaction of a cotranslational chaperone with the eukaryotic ribosome

(2014) Yixiao Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Functional conservation and divergence of J-domain-containing ZUO1/ZRF orthologs throughout evolution

(2014) Dong-Hong Chen et al.   PLANTA

Multidrug resistance in fungi: regulation of transporter-encoding gene expression

(2014) Sanjoy Paul et al.   Frontiers in Physiology

Co-translational targeting and translocation of proteins to the endoplasmic reticulum

(2013) Yvonne Nyathi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Cotranslational Function of Ribosome-Associated Hsp70 in Eukaryotic Protein Homeostasis

(2013) Felix Willmund et al.   CELL

Interaction of Nascent Chains with the Ribosomal Tunnel Proteins Rpl4, Rpl17, and Rpl39 ofSaccharomyces cerevisiae

(2013) Ying Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Human Specialized DNA Polymerases and Non-B DNA: Vital Relationships to Preserve Genome Integrity

(2013) Anne-Sophie Boyer et al.   JOURNAL OF MOLECULAR BIOLOGY

The Ribosome as a Hub for Protein Quality Control

(2013) Sebastian Pechmann et al.   MOLECULAR CELL

Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation

(2013) Danielle L Swaney et al.   NATURE METHODS

Lysine Succinylation Is a Frequently Occurring Modification in Prokaryotes and Eukaryotes and Extensively Overlaps with Acetylation

(2013) Brian T. Weinert et al.   Cell Reports

Nutritional Control of Growth and Development in Yeast

(2012) J. R. Broach   GENETICS

Unfolding of the C-Terminal Domain of the J-Protein Zuo1 Releases Autoinhibition and Activates Pdr1-Dependent Transcription

(2012) Jeanette K. Ducett et al.   JOURNAL OF MOLECULAR BIOLOGY

Biology of the Heat Shock Response and Protein Chaperones: Budding Yeast (Saccharomyces cerevisiae) as a Model System

(2012) J. Verghese et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Ribosome-Associated Complex and Ssb Are Required for Translational Repression Induced by Polylysine Segments within Nascent Chains

(2012) M. Chiabudini et al.   MOLECULAR AND CELLULAR BIOLOGY

Structure and Dynamics of the ATP-Bound Open Conformation of Hsp70 Chaperones

(2012) Roman Kityk et al.   MOLECULAR CELL

Cryo-EM structures of Arx1 and maturation factors Rei1 and Jjj1 bound to the 60S ribosomal subunit

(2012) Basil J Greber et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural characterization of a eukaryotic chaperone—the ribosome-associated complex

(2012) Christoph Leidig et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ribosome-associated chaperones as key players in proteostasis

(2012) Steffen Preissler et al.   TRENDS IN BIOCHEMICAL SCIENCES

The flip side of the coin: Role of ZRF1 and histone H2A ubiquitination in transcriptional activation

(2011) Holger Richly et al.   CELL CYCLE

Polytopic membrane protein folding at L17 in the ribosome tunnel initiates cyclical changes at the translocon

(2011) Pen-Jen Lin et al.   JOURNAL OF CELL BIOLOGY

The Chaperone Network Connected to Human Ribosome-Associated Complex

(2011) H. Jaiswal et al.   MOLECULAR AND CELLULAR BIOLOGY

The role of protein disorder in the 14-3-3 interaction network

(2011) Diego M. Bustos   Molecular BioSystems

Role for the molecular chaperones Zuo1 and Ssz1 in quorum sensing via activation of the transcription factor Pdr1

(2011) A. J. Prunuske et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structure of the Eukaryotic 60S Ribosomal Subunit in Complex with Initiation Factor 6

(2011) S. Klinge et al.   SCIENCE

The Structure of the Eukaryotic Ribosome at 3.0 A Resolution

(2011) A. Ben-Shem et al.   SCIENCE

Structural basis of 14-3-3 protein functions

(2011) Tomas Obsil et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The 14-3-3 proteins in regulation of cellular metabolism

(2011) Rune Kleppe et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The ribosome-bound Hsp70 homolog Ssb of Saccharomyces cerevisiae

(2010) Kristin Peisker et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A dual function for chaperones SSB–RAC and the NAC nascent polypeptide–associated complex on ribosomes

(2010) Ansgar Koplin et al.   JOURNAL OF CELL BIOLOGY

A ribosome-anchored chaperone network that facilitates eukaryotic ribosome biogenesis

(2010) Véronique Albanèse et al.   JOURNAL OF CELL BIOLOGY

Transcriptional activation of polycomb-repressed genes by ZRF1

(2010) Holger Richly et al.   NATURE

The HSP70 chaperone machinery: J proteins as drivers of functional specificity

(2010) Harm H. Kampinga et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

α-Helical nascent polypeptide chains visualized within distinct regions of the ribosomal exit tunnel

(2010) Shashi Bhushan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Combining peptide recognition specificity and context information for the prediction of the 14-3-3-mediated interactome in S. cerevisiae and H. sapiens

(2010) Simona Panni et al.   PROTEOMICS

Protein targeting by the signal recognition particle

(2009) Przemyslaw Grudnik et al.   BIOLOGICAL CHEMISTRY

Fidelity at the Molecular Level: Lessons from Protein Synthesis

(2009) Hani S. Zaher et al.   CELL

The Hsp70 homolog Ssb is essential for glucose sensing via the SNF1 kinase network

(2009) U. von Plehwe et al.   GENES & DEVELOPMENT

Structural Analysis of the Ribosome-associated Complex (RAC) Reveals an Unusual Hsp70/Hsp40 Interaction

(2009) Jocelyne Fiaux et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An atlas of chaperone–protein interactions in Saccharomyces cerevisiae: implications to protein folding pathways in the cell

(2009) Yunchen Gong et al.   Molecular Systems Biology

Sending Signals Dynamically

(2009) R. G. Smock et al.   SCIENCE

Two nucleotide substitutions in the A-site of yeast 18S rRNA affect translation and differentiate the interaction of ribosomes with aminoglycoside antibiotics

(2008) S. Tselika et al.   BIOCHIMIE

A Multidimensional Chromatography Technology for In-depth Phosphoproteome Analysis

(2008) Claudio P. Albuquerque et al.   MOLECULAR & CELLULAR PROTEOMICS

Ribosome-associated Complex Binds to Ribosomes in Close Proximity of Rpl31 at the Exit of the Polypeptide Tunnel in Yeast

(2008) Kristin Peisker et al.   MOLECULAR BIOLOGY OF THE CELL