Pre-metastatic cancer exosomes induce immune surveillance by patrolling monocytes at the metastatic niche

Heterogeneity of Metastatic Melanoma

(2016) Sarvenaz Zand et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis

(2016) Annette Becker et al.   CANCER CELL

Metastatic Latency and Immune Evasion through Autocrine Inhibition of WNT

(2016) Srinivas Malladi et al.   CELL

Focus on Extracellular Vesicles: New Frontiers of Cell-to-Cell Communication in Cancer

(2016) Chiara Ciardiello et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Extracellular vesicles swarm the cancer microenvironment: from tumor–stroma communication to drug intervention

(2016) F Wendler et al.   ONCOGENE

A Novel Role for Microphthalmia-Associated Transcription Factor–Regulated Pigment Epithelium-Derived Factor during Melanoma Progression

(2015) Soheil S. Dadras et al.   AMERICAN JOURNAL OF PATHOLOGY

Epigenetic regulation in human melanoma: past and future

(2015) Debina Sarkar et al.   Epigenetics

Intravital live cell triggered imaging system reveals monocyte patrolling and macrophage migration in atherosclerotic arteries

(2015) Sara McArdle et al.   JOURNAL OF BIOMEDICAL OPTICS

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

(2015) Bruno Costa-Silva et al.   NATURE CELL BIOLOGY

Exosomes in bodily fluids are a highly stable resource of disease biomarkers

(2015) Stephanie Boukouris et al.   Proteomics Clinical Applications

Patrolling monocytes control tumor metastasis to the lung

(2015) R. N. Hanna et al.   SCIENCE

Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes

(2015) Shivakumar Keerthikumar et al.   Oncotarget

Immune surveillance of the lung by migrating tissue monocytes

(2015) Mathieu P Rodero et al.   eLife

The New Deal: A Potential Role for Secreted Vesicles in Innate Immunity and Tumor Progression

(2015) Alberto Benito-Martin et al.   Frontiers in Immunology

Pigment Epithelium-Derived Factor Blocks Tumor Extravasation by Suppressing Amoeboid Morphology and Mesenchymal Proteolysis

(2015) Omar Ladhani et al.   NEOPLASIA

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

Cancer Exosomes Perform Cell-Independent MicroRNA Biogenesis and Promote Tumorigenesis

(2014) Sonia A. Melo et al.   CANCER CELL

Biogenesis and secretion of exosomes

(2014) Joanna Kowal et al.   CURRENT OPINION IN CELL BIOLOGY

The cellular and molecular origin of tumor-associated macrophages

(2014) R. A. Franklin et al.   SCIENCE

Tetraspanins in Extracellular Vesicle Formation and Function

(2014) Zoraida Andreu et al.   Frontiers in Immunology

Regulatory and Functional Connection of Microphthalmia-Associated Transcription Factor and Anti-Metastatic Pigment Epithelium Derived Factor in Melanoma

(2014) Asunción Fernández-Barral et al.   NEOPLASIA

The pre-metastatic niche: finding common ground

(2013) Jaclyn Sceneay et al.   CANCER AND METASTASIS REVIEWS

Nr4a1-Dependent Ly6Clow Monocytes Monitor Endothelial Cells and Orchestrate Their Disposal

(2013) Leo M. Carlin et al.   CELL

The many facets of PEDF in drug discovery and disease: a diamond in the rough or split personality disorder?

(2013) Susan E Craword et al.   Expert Opinion on Drug Discovery

Visualization and in vivo tracking of the exosomes of murine melanoma B16-BL6 cells in mice after intravenous injection

(2013) Yuki Takahashi et al.   JOURNAL OF BIOTECHNOLOGY

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

Exosomes in tumor microenvironment influence cancer progression and metastasis

(2013) Christoph Kahlert et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development

(2013) P. Kucharzewska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rab27a Supports Exosome-Dependent and -Independent Mechanisms That Modify the Tumor Microenvironment and Can Promote Tumor Progression

(2012) A. Bobrie et al.   CANCER RESEARCH

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2012) Héctor Peinado et al.   NATURE MEDICINE

Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation

(2012) Hina Kalra et al.   PLOS BIOLOGY

Depletion and Reconstitution of Macrophages in Mice

(2012) Shelley B. Weisser et al.   Jove-Journal of Visualized Experiments

Microvesicles: Messengers and mediators of tumor progression

(2011) Khalid Al-Nedawi et al.   CELL CYCLE

NR4A1 (Nur77) Deletion Polarizes Macrophages Toward an Inflammatory Phenotype and Increases Atherosclerosis

(2011) Richard N. Hanna et al.   CIRCULATION RESEARCH

Pigment Epithelium-derived Factor (PEDF) Promotes Tumor Cell Death by Inducing Macrophage Membrane Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)

(2011) Tsung-Chuan Ho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The secreted factors responsible for pre-metastatic niche formation: Old sayings and new thoughts

(2011) Héctor Peinado et al.   SEMINARS IN CANCER BIOLOGY

uPAR mediates anticancer activity of PEDF

(2010) Crispin R. Dass et al.   CANCER BIOLOGY & THERAPY

Human CD14dim Monocytes Patrol and Sense Nucleic Acids and Viruses via TLR7 and TLR8 Receptors

(2010) Jérôme Cros et al.   IMMUNITY

Microparticles in Cancer

(2010) Janusz Rak   SEMINARS IN THROMBOSIS AND HEMOSTASIS

‘Loss of pigment epithelium-derived factor enables migration, invasion and metastatic spread of human melanoma’

(2009) J L Orgaz et al.   ONCOGENE

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY