标题
Nrl knockdown by AAV-delivered CRISPR/Cas9 prevents retinal degeneration in mice
作者
关键词
-
出版物
Nature Communications
Volume 8, Issue -, Pages 14716
出版商
Springer Nature
发表日期
2017-03-15
DOI
10.1038/ncomms14716
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Recruitment of Rod Photoreceptors from Short-Wavelength-Sensitive Cones during the Evolution of Nocturnal Vision in Mammals
- (2016) Jung-Woong Kim et al. DEVELOPMENTAL CELL
- Ciliopathy-associated IQCB1/NPHP5 protein is required for mouse photoreceptor outer segment formation
- (2016) Cecinio C. Ronquillo et al. FASEB JOURNAL
- In Vivo CRISPR/Cas9 Gene Editing Corrects Retinal Dystrophy in the S334ter-3 Rat Model of Autosomal Dominant Retinitis Pigmentosa
- (2016) Benjamin Bakondi et al. MOLECULAR THERAPY
- High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects
- (2016) Benjamin P. Kleinstiver et al. NATURE
- Analyzing CRISPR genome-editing experiments with CRISPResso
- (2016) Luca Pinello et al. NATURE BIOTECHNOLOGY
- Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo
- (2016) Hao Yin et al. NATURE BIOTECHNOLOGY
- A multifunctional AAV–CRISPR–Cas9 and its host response
- (2016) Wei Leong Chew et al. NATURE METHODS
- Rhodopsin targeted transcriptional silencing by DNA-binding
- (2016) Salvatore Botta et al. eLife
- Rod-Derived Cone Viability Factor Promotes Cone Survival by Stimulating Aerobic Glycolysis
- (2015) Najate Aït-Ali et al. CELL
- Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice
- (2015) Aditya Venkatesh et al. JOURNAL OF CLINICAL INVESTIGATION
- In vivo genome editing using Staphylococcus aureus Cas9
- (2015) F. Ann Ran et al. NATURE
- Therapeutic genome editing: prospects and challenges
- (2015) David Benjamin Turitz Cox et al. NATURE MEDICINE
- limma powers differential expression analyses for RNA-sequencing and microarray studies
- (2015) Matthew E. Ritchie et al. NUCLEIC ACIDS RESEARCH
- Rationally engineered Cas9 nucleases with improved specificity
- (2015) I. M. Slaymaker et al. SCIENCE
- Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy
- (2015) C. Long et al. SCIENCE
- In vivo gene editing in dystrophic mouse muscle and muscle stem cells
- (2015) M. Tabebordbar et al. SCIENCE
- In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy
- (2015) C. E. Nelson et al. SCIENCE
- A short N-terminal domain of HDAC4 preserves photoreceptors and restores visual function in retinitis pigmentosa
- (2015) Xinzheng Guo et al. Nature Communications
- CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling
- (2014) Randall J. Platt et al. CELL
- Development and Applications of CRISPR-Cas9 for Genome Engineering
- (2014) Patrick D. Hsu et al. CELL
- Regulation of a novel isoform of Receptor Expression Enhancing Protein REEP6 in rod photoreceptors by bZIP transcription factor NRL
- (2014) Hong Hao et al. HUMAN MOLECULAR GENETICS
- Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial
- (2014) Robert E MacLaren et al. LANCET
- Improving CRISPR-Cas nuclease specificity using truncated guide RNAs
- (2014) Yanfang Fu et al. NATURE BIOTECHNOLOGY
- Genes and mutations causing retinitis pigmentosa
- (2013) S P Daiger et al. CLINICAL GENETICS
- A Comprehensive Review of Retinal Gene Therapy
- (2013) Shannon E Boye et al. MOLECULAR THERAPY
- Genome engineering using the CRISPR-Cas9 system
- (2013) F Ann Ran et al. Nature Protocols
- Reprogramming of adult rod photoreceptors prevents retinal degeneration
- (2013) C. L. Montana et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
- (2013) Ophir Shalem et al. SCIENCE
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Preservation of Cone Photoreceptors after a Rapid yet Transient Degeneration and Remodeling in Cone-Only Nrl-/- Mouse Retina
- (2012) J. E. Roger et al. JOURNAL OF NEUROSCIENCE
- NIH Image to ImageJ: 25 years of image analysis
- (2012) Caroline A Schneider et al. NATURE METHODS
- Transcriptional Regulation of Rod Photoreceptor Homeostasis Revealed by In Vivo NRL Targetome Analysis
- (2012) Hong Hao et al. PLoS Genetics
- Zinc-finger-based transcriptional repression of rhodopsin in a model of dominant retinitis pigmentosa
- (2011) Claudio Mussolino et al. EMBO Molecular Medicine
- Cone photoreceptors are the main targets for gene therapy of NPHP5 (IQCB1) or NPHP6 (CEP290) blindness: generation of an all-cone Nphp6 hypomorph mouse that mimics the human retinal ciliopathy
- (2011) Artur V. Cideciyan et al. HUMAN MOLECULAR GENETICS
- Transcriptional Regulation of Neural Retina Leucine Zipper (Nrl), a Photoreceptor Cell Fate Determinant
- (2011) Cynthia L. Montana et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Suppression and Replacement Gene Therapy for Autosomal Dominant Disease in a Murine Model of Dominant Retinitis Pigmentosa
- (2011) Sophia Millington-Ward et al. MOLECULAR THERAPY
- CNTF and retina
- (2011) Rong Wen et al. PROGRESS IN RETINAL AND EYE RESEARCH
- BEDTools: a flexible suite of utilities for comparing genomic features
- (2010) Aaron R. Quinlan et al. BIOINFORMATICS
- Transcriptional regulation of photoreceptor development and homeostasis in the mammalian retina
- (2010) Anand Swaroop et al. NATURE REVIEWS NEUROSCIENCE
- The orphan nuclear hormone receptor ERR controls rod photoreceptor survival
- (2010) A. Onishi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
- (2009) M. D. Robinson et al. BIOINFORMATICS
- GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists
- (2009) Eran Eden et al. BMC BIOINFORMATICS
- Rod differentiation factor NRL activates the expression of nuclear receptor NR2E3 to suppress the development of cone photoreceptors
- (2008) Edwin C.T. Oh et al. BRAIN RESEARCH
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