Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

MicroRNA Functions in Brite/Brown Fat — Novel Perspectives towards Anti-Obesity Strategies

(2014) Michael Karbiener et al.   Computational and Structural Biotechnology Journal

Long noncoding RNAs regulate adipogenesis

(2013) Lei Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IGF-I, IGF-II, and Insulin Stimulate Different Gene Expression Responses through Binding to the IGF-I Receptor

(2013) Soetkin Versteyhe et al.   Frontiers in Endocrinology

Glypican-4 Enhances Insulin Signaling via Interaction With the Insulin Receptor and Serves as a Novel Adipokine

(2012) S. Ussar et al.   DIABETES

Impaired thermogenesis and adipose tissue development in mice with fat-specific disruption of insulin and IGF-1 signalling

(2012) Jeremie Boucher et al.   Nature Communications

Insulin and Insulin-like Growth Factor-1 Receptors Act as Ligand-specific Amplitude Modulators of a Common Pathway Regulating Gene Transcription

(2010) Jeremie Boucher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Kinase-Independent Role for Unoccupied Insulin and IGF-1 Receptors in the Control of Apoptosis

(2010) J. Boucher et al.   Science Signaling

A Layered Grammar of Graphics

(2009) Hadley Wickham   JOURNAL OF COMPUTATIONAL AND GRAPHICAL STATISTICS

Solution Structure of Ectodomains of the Insulin Receptor Family: The Ectodomain of the Type 1 Insulin-Like Growth Factor Receptor Displays Asymmetry of Ligand Binding Accompanied by Limited Conformational Change

(2009) Andrew E. Whitten et al.   JOURNAL OF MOLECULAR BIOLOGY

Harmonic oscillator model of the insulin and IGF1 receptors’ allosteric binding and activation

(2009) Vladislav V Kiselyov et al.   Molecular Systems Biology

Insulin-like growth factor I (IGF-I) is a more potent regulator of gene expression than insulin in primary human myoblasts and myotubes

(2008) Jane Palsgaard et al.   GROWTH HORMONE & IGF RESEARCH

Alanine Scanning of a Putative Receptor Binding Surface of Insulin-like Growth Factor-I

(2008) Lisbeth Gauguin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Phosphotyrosine Interactome of the Insulin Receptor Family and Its Substrates IRS-1 and IRS-2

(2008) Stefan Hanke et al.   MOLECULAR & CELLULAR PROTEOMICS

Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2

(2008) Jinhua Wu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dissection of the insulin signaling pathway via quantitative phosphoproteomics

(2008) M. Kruger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA