A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue

Antimalarial Benzoxaboroles Target Plasmodium falciparum Leucyl-tRNA Synthetase

(2016) Ebere Sonoiki et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Cryptosporidium and Toxoplasma Parasites Are Inhibited by a Benzoxaborole Targeting Leucyl-tRNA Synthetase

(2016) Andrés Palencia et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Novel investigational therapies for onychomycosis: an update

(2016) Aditya K. Gupta et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

CRISPR-Cas9-modifiedpfmdr1protectsPlasmodium falciparumasexual blood stages and gametocytes against a class of piperazine-containing compounds but potentiates artemisinin-based combination therapy partner drugs

(2016) Caroline L. Ng et al.   MOLECULAR MICROBIOLOGY

Impact of Antimalarial Treatment and Chemoprevention on the Drug Sensitivity of Malaria Parasites Isolated from Ugandan Children

(2015) Patrick Tumwebaze et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Benzoxaborole Antimalarial Agents. Part 4. Discovery of Potent 6-(2-(Alkoxycarbonyl)pyrazinyl-5-oxy)-1,3-dihydro-1-hydroxy-2,1-benzoxaboroles

(2015) Yong-Kang Zhang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Reconstitution of CPSF active in polyadenylation: recognition of the polyadenylation signal by WDR33

(2014) Lars Schönemann et al.   GENES & DEVELOPMENT

Delineating the Structural Blueprint of the Pre-mRNA 3'-End Processing Machinery

(2014) K. Xiang et al.   MOLECULAR AND CELLULAR BIOLOGY

Discovery of a Novel Class of Boron-Based Antibacterials with Activity against Gram-Negative Bacteria

(2013) Vincent Hernandez et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The interplay between drug resistance and fitness in malaria parasites

(2013) Philip J. Rosenthal   MOLECULAR MICROBIOLOGY

A molecular marker of artemisinin-resistant Plasmodium falciparum malaria

(2013) Frédéric Ariey et al.   NATURE

Asexual Populations of the Human Malaria Parasite, Plasmodium falciparum, Use a Two-Step Genomic Strategy to Acquire Accurate, Beneficial DNA Amplifications

(2013) Jennifer L. Guler et al.   PLoS Pathogens

Boron-based phosphodiesterase inhibitors show novel binding of boron to PDE4 bimetal center

(2012) Yvonne R. Freund et al.   FEBS LETTERS

P. falciparum In Vitro Killing Rates Allow to Discriminate between Different Antimalarial Mode-of-Action

(2012) Laura M. Sanz et al.   PLoS One

Synthesis and SAR of novel benzoxaboroles as a new class of β-lactamase inhibitors

(2011) Yi Xia et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Benzoxaborole antimalarial agents. Part 2: Discovery of fluoro-substituted 7-(2-carboxyethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaboroles

(2011) Yong-Kang Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Boron-containing inhibitors of synthetases

(2011) Stephen J. Baker et al.   CHEMICAL SOCIETY REVIEWS

Boron-based drugs as antiprotozoals

(2011) Robert T. Jacobs et al.   CURRENT OPINION IN INFECTIOUS DISEASES

In Vitro Sensitivities of Plasmodium falciparum to Different Antimalarial Drugs in Uganda

(2010) S. L. Nsobya et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Discovery of Novel Orally Bioavailable Oxaborole 6-Carboxamides That Demonstrate Cure in a Murine Model of Late-Stage Central Nervous System African Trypanosomiasis

(2010) B. Nare et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Design and synthesis of boron-containing PDE4 inhibitors using soft-drug strategy for potential dermatologic anti-inflammatory application

(2010) Yong-Kang Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and structure–activity relationships of novel benzoxaboroles as a new class of antimalarial agents

(2010) Yong-Kang Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Pre-mRNA 3′-end processing complex assembly and function

(2010) Serena Chan et al.   Wiley Interdisciplinary Reviews-RNA

Improved Murine Model of Malaria Using Plasmodium falciparum Competent Strains and Non-Myelodepleted NOD-scid IL2R null Mice Engrafted with Human Erythrocytes

(2009) M. B. Jimenez-Diaz et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Therapeutic potential of boron-containing compounds

(2009) Stephen J Baker et al.   Future Medicinal Chemistry

Artemisinin Resistance inPlasmodium falciparumMalaria

(2009) Arjen M. Dondorp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY