Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility

Multipronged approach to identify and validate a novel upstream regulator ofSncgin mouse retinal ganglion cells

(2016) Sumana R. Chintalapudi et al.   FEBS Journal

Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma

(2016) Jessica N Cooke Bailey et al.   NATURE GENETICS

Webinar   Characterizing cancers from liquid biopsies and FFPE samples: The rise of targeted sequencing panels AUDIO

(2016) P. M. Williams et al.   SCIENCE

Isolation and Molecular Profiling of Primary Mouse Retinal Ganglion Cells: Comparison of Phenotypes from Healthy and Glaucomatous Retinas

(2016) Sumana R. Chintalapudi et al.   Frontiers in Aging Neuroscience

A common variant near TGFBR3 is associated with primary open angle glaucoma

(2015) Zheng Li et al.   HUMAN MOLECULAR GENETICS

ARHGEF12 influences the risk of glaucoma by increasing intraocular pressure

(2015) H. Springelkamp et al.   HUMAN MOLECULAR GENETICS

Genetic variation in offspring indirectly influences the quality of maternal behaviour in mice

(2015) David George Ashbrook et al.   eLife

Novel Endogenous Glycan Therapy for Retinal Diseases: Safety, In Vitro Stability, Ocular Pharmacokinetic Modeling, and Biodistribution

(2014) Shankar Swaminathan et al.   AAPS Journal

A genome-wide association study of intra-ocular pressure suggests a novel association in the gene FAM125B in the TwinsUK cohort

(2014) A. Nag et al.   HUMAN MOLECULAR GENETICS

Common variants near ABCA1, AFAP1 and GMDS confer risk of primary open-angle glaucoma

(2014) Puya Gharahkhani et al.   NATURE GENETICS

Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma

(2014) Pirro G Hysi et al.   NATURE GENETICS

Common variants near ABCA1 and in PMM2 are associated with primary open-angle glaucoma

(2014) Yuhong Chen et al.   NATURE GENETICS

High prevalence of genetic variants previously associated with Brugada syndrome in new exome data

(2013) B Risgaard et al.   CLINICAL GENETICS

Calcium channels and their blockers in intraocular pressure and glaucoma

(2013) Chihiro Mayama   EUROPEAN JOURNAL OF PHARMACOLOGY

Whole exome sequencing in dominant cataract identifies a new causative factor, CRYBA2, and a variety of novel alleles in known genes

(2013) Linda M. Reis et al.   HUMAN GENETICS

Mitonuclear protein imbalance as a conserved longevity mechanism

(2013) Riekelt H. Houtkooper et al.   NATURE

Genetic modulation of the iris transillumination defect: a systems genetics analysis using the expanded family of BXD glaucoma strains

(2013) Shankar Swaminathan et al.   Pigment Cell & Melanoma Research

Systems Genetics of Metabolism: The Use of the BXD Murine Reference Panel for Multiscalar Integration of Traits

(2012) Pénélope A. Andreux et al.   CELL

Genetic architecture supports mosaic brain evolution and independent brain–body size regulation

(2012) Reinmar Hager et al.   Nature Communications

Common Variants at 9p21 and 8q22 Are Associated with Increased Susceptibility to Optic Nerve Degeneration in Glaucoma

(2012) Janey L. Wiggs et al.   PLoS Genetics

Biodegradable Ocular Inserts for Sustained Delivery of Brimonidine Tartarate: Preparation and In Vitro/In Vivo Evaluation

(2011) Mona Hassan Aburahma et al.   AAPS PHARMSCITECH

Identification of a novel loss-of-function calcium channel gene mutation in short QT syndrome (SQTS6)

(2011) C. Templin et al.   EUROPEAN HEART JOURNAL

Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1

(2011) Kathryn P Burdon et al.   NATURE GENETICS

Phenotype Associated With Mutation in the Recently Identified Autosomal Dominant Retinitis Pigmentosa KLHL7 Gene

(2010) Therése Hugosson   ARCHIVES OF OPHTHALMOLOGY

A Genome-wide Drosophila Screen for Heat Nociception Identifies α2δ3 as an Evolutionarily Conserved Pain Gene

(2010) G. Gregory Neely et al.   CELL

Novel SNPs of the bovine CACNA2D1 gene and their association with carcass and meat quality traits

(2010) Zheng Rong Yuan et al.   MOLECULAR BIOLOGY REPORTS

Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma

(2010) Gudmar Thorleifsson et al.   NATURE GENETICS

Genetic Pathways Regulating Glutamate Levels in Retinal Müller Cells

(2010) Monica M. Jablonski et al.   NEUROCHEMICAL RESEARCH

Neurodegeneration in glaucoma: progression and calcium-dependent intracellular mechanisms

(2010) S.D. Crish et al.   NEUROSCIENCE

Use of calcium channel blockers for glaucoma

(2010) Makoto Araie et al.   PROGRESS IN RETINAL AND EYE RESEARCH

The trabecular meshwork outflow pathways: Structural and functional aspects

(2009) Ernst R. Tamm   EXPERIMENTAL EYE RESEARCH

Primary Open-Angle Glaucoma

(2009) Young H. Kwon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Heritability of intraocular pressure: a classical twin study

(2008) F Carbonaro et al.   BRITISH JOURNAL OF OPHTHALMOLOGY