ARHGEF12 influences the risk of glaucoma by increasing intraocular pressure

A genome-wide association study of intra-ocular pressure suggests a novel association in the gene FAM125B in the TwinsUK cohort

(2014) A. Nag et al.   HUMAN MOLECULAR GENETICS

Common variants near ABCA1, AFAP1 and GMDS confer risk of primary open-angle glaucoma

(2014) Puya Gharahkhani et al.   NATURE GENETICS

Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma

(2014) Pirro G Hysi et al.   NATURE GENETICS

Database resources of the National Center for Biotechnology Information

(2014)   NUCLEIC ACIDS RESEARCH

The Rotterdam Study: 2014 objectives and design update

(2013) Albert Hofman et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Exon-level expression profiling of ocular tissues

(2013) Alex H. Wagner et al.   EXPERIMENTAL EYE RESEARCH

PDZ-RhoGEF and LARG Are Essential for Embryonic Development and Provide a Link between Thrombin and LPA Receptors and Rho Activation

(2013) Constantinos M. Mikelis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Plasticity and Fibrogenic Activity of Trabecular Meshwork Cells by Rho GTPase Signaling

(2013) Padmanabhan P. Pattabiraman et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus

(2013) Yi Lu et al.   NATURE GENETICS

Ensembl 2014

(2013) Paul Flicek et al.   NUCLEIC ACIDS RESEARCH

Raine Eye Health Study: Design, Methodology and Baseline Prevalence of Ophthalmic Disease in a Birth-cohort Study of Young Adults

(2013) Seyhan Yazar et al.   OPHTHALMIC GENETICS

Birth of a cohort — the first 20 years of the Raine study

(2012) Charlotte M McKnight et al.   MEDICAL JOURNAL OF AUSTRALIA

Common Genetic Determinants of Intraocular Pressure and Primary Open-Angle Glaucoma

(2012) Leonieke M. E. van Koolwijk et al.   PLoS Genetics

Identification of Novel Ras-Cooperating Oncogenes inDrosophila melanogaster: A RhoGEF/Rho-Family/JNK Pathway Is a Central Driver of Tumorigenesis

(2011) Anthony M. Brumby et al.   GENETICS

Common genetic variants associated with open-angle glaucoma

(2011) Wishal D. Ramdas et al.   HUMAN MOLECULAR GENETICS

Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1

(2011) Kathryn P Burdon et al.   NATURE GENETICS

Genotype Imputation with Thousands of Genomes

(2011) Bryan Howie et al.   G3-Genes Genomes Genetics

LocusZoom: regional visualization of genome-wide association scan results

(2010) R. J. Pruim et al.   BIOINFORMATICS

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

ProbABEL package for genome-wide association analysis of imputed data

(2010) Yurii S Aulchenko et al.   BMC BIOINFORMATICS

Binding of PDZ-RhoGEF to ATP-binding Cassette Transporter A1 (ABCA1) Induces Cholesterol Efflux through RhoA Activation and Prevention of Transporter Degradation

(2010) Keiichiro Okuhira et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rho GTPase-mediated cytoskeletal organization in Schlemm's canal cells play a critical role in the regulation of aqueous humor outflow facility

(2010) Janardan Kumar et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma

(2010) Gudmar Thorleifsson et al.   NATURE GENETICS

Genotype imputation for genome-wide association studies

(2010) Jonathan Marchini et al.   NATURE REVIEWS GENETICS

The Heritability of Ocular Traits

(2010) Paul G. Sanfilippo et al.   SURVEY OF OPHTHALMOLOGY

Origins and functional impact of copy number variation in the human genome

(2009) Donald F. Conrad et al.   NATURE

Twins Eye Study in Tasmania (TEST): Rationale and Methodology to Recruit and Examine Twins

(2009) David A. Mackey et al.   Twin Research and Human Genetics

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics