Stabilization of Foxp3 expression by CRISPR-dCas9-based epigenome editing in mouse primary T cells
出版年份 2017 全文链接
标题
Stabilization of Foxp3 expression by CRISPR-dCas9-based epigenome editing in mouse primary T cells
作者
关键词
Treg, Foxp3, CRISPR, dCas9, TET1, p300, Epigenome editing
出版物
Epigenetics & Chromatin
Volume 10, Issue 1, Pages -
出版商
Springer Nature
发表日期
2017-05-08
DOI
10.1186/s13072-017-0129-1
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing
- (2016) Angelo Amabile et al. CELL
- Control of Foxp3 stability through modulation of TET activity
- (2016) Xiaojing Yue et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Vitamin C Facilitates Demethylation of theFoxp3Enhancer in a Tet-Dependent Manner
- (2016) Varun Sasidharan Nair et al. JOURNAL OF IMMUNOLOGY
- DNA Demethylation of the Foxp3 Enhancer Is Maintained through Modulation of Ten-Eleven-Translocation and DNA Methyltransferases
- (2016) Varun Sasidharan Nair et al. MOLECULES AND CELLS
- Targeted DNA demethylation in vivo using dCas9–peptide repeat and scFv–TET1 catalytic domain fusions
- (2016) Sumiyo Morita et al. NATURE BIOTECHNOLOGY
- Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment
- (2016) Yohko Kitagawa et al. NATURE IMMUNOLOGY
- Editing the epigenome: technologies for programmable transcription and epigenetic modulation
- (2016) Pratiksha I Thakore et al. NATURE METHODS
- Comparison of Cas9 activators in multiple species
- (2016) Alejandro Chavez et al. NATURE METHODS
- Repurposing the CRISPR-Cas9 system for targeted DNA methylation
- (2016) Aleksandar Vojta et al. NUCLEIC ACIDS RESEARCH
- A CRISPR-based approach for targeted DNA demethylation
- (2016) Xingxing Xu et al. Cell Discovery
- Crystal Structure of Staphylococcus aureus Cas9
- (2015) Hiroshi Nishimasu et al. CELL
- Hydrogen Sulfide Promotes Tet1- and Tet2-Mediated Foxp3 Demethylation to Drive Regulatory T Cell Differentiation and Maintain Immune Homeostasis
- (2015) Ruili Yang et al. IMMUNITY
- Suppression of Th2 and Tfh immune reactions by Nr4a receptors in mature T reg cells
- (2015) Takashi Sekiya et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Gene therapy returns to centre stage
- (2015) Luigi Naldini NATURE
- In vivo genome editing using Staphylococcus aureus Cas9
- (2015) F. Ann Ran et al. NATURE
- Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers
- (2015) Isaac B Hilton et al. NATURE BIOTECHNOLOGY
- Functional annotation of native enhancers with a Cas9–histone demethylase fusion
- (2015) Nicola A Kearns et al. NATURE METHODS
- Antigen receptor-mediated depletion of FOXP3 in induced regulatory T-lymphocytes via PTPN2 and FOXO1
- (2015) Evita Bothur et al. Nature Communications
- Conditionally Stabilized dCas9 Activator for Controlling Gene Expression in Human Cell Reprogramming and Differentiation
- (2015) Diego Balboa et al. Stem Cell Reports
- CCTop: An Intuitive, Flexible and Reliable CRISPR/Cas9 Target Prediction Tool
- (2015) Manuel Stemmer et al. PLoS One
- Control of the Inheritance of Regulatory T Cell Identity by a cis Element in the Foxp3 Locus
- (2014) Yongqiang Feng et al. CELL
- Epigenetic Regulation of Foxp3 Expression in Regulatory T Cells by DNA Methylation
- (2014) G. Lal et al. JOURNAL OF IMMUNOLOGY
- CRISPR-Cas systems for editing, regulating and targeting genomes
- (2014) Jeffry D Sander et al. NATURE BIOTECHNOLOGY
- Comparison of TALE designer transcription factors and the CRISPR/dCas9 in regulation of gene expression by targeting enhancers
- (2014) Xuefei Gao et al. NUCLEIC ACIDS RESEARCH
- Differential roles of epigenetic changes and Foxp3 expression in regulatory T cell-specific transcriptional regulation
- (2014) H. Morikawa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibitors of enhancer of zeste homolog 2 (EZH2) activate tumor-suppressor microRNAs in human cancer cells
- (2014) S Hibino et al. Oncogenesis
- Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
- (2013) Lei S. Qi et al. CELL
- CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
- (2013) Luke A. Gilbert et al. CELL
- Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells
- (2013) Yukihiro Furusawa et al. NATURE
- Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation
- (2013) Nicholas Arpaia et al. NATURE
- Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins
- (2013) Morgan L Maeder et al. NATURE BIOTECHNOLOGY
- DNA targeting specificity of RNA-guided Cas9 nucleases
- (2013) Patrick D Hsu et al. NATURE BIOTECHNOLOGY
- High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity
- (2013) Vikram Pattanayak et al. NATURE BIOTECHNOLOGY
- RNA-guided gene activation by CRISPR-Cas9–based transcription factors
- (2013) Pablo Perez-Pinera et al. NATURE METHODS
- CRISPR RNA–guided activation of endogenous human genes
- (2013) Morgan L Maeder et al. NATURE METHODS
- Plasticity of Foxp3+ T Cells Reflects Promiscuous Foxp3 Expression in Conventional T Cells but Not Reprogramming of Regulatory T Cells
- (2012) Takahisa Miyao et al. IMMUNITY
- T Cell Receptor Stimulation-Induced Epigenetic Changes and Foxp3 Expression Are Independent and Complementary Events Required for Treg Cell Development
- (2012) Naganari Ohkura et al. IMMUNITY
- Extrathymically generated regulatory T cells control mucosal TH2 inflammation
- (2012) Steven Z. Josefowicz et al. NATURE
- A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells
- (2012) Wenxian Fu et al. NATURE IMMUNOLOGY
- SOCS1 is essential for regulatory T cell functions by preventing loss of Foxp3 expression as well as IFN-γ and IL-17A production
- (2011) Reiko Takahashi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Identification of T helper type 1–like, Foxp3+ regulatory T cells in human autoimmune disease
- (2011) Margarita Dominguez-Villar et al. NATURE MEDICINE
- Massive ex Vivo Expansion of Human Natural Regulatory T Cells (Tregs) with Minimal Loss of in Vivo Functional Activity
- (2011) K. L. Hippen et al. Science Translational Medicine
- The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells
- (2011) Takashi Sekiya et al. Nature Communications
- Transcription factors Foxo3a and Foxo1 couple the E3 ligase Cbl-b to the induction of Foxp3 expression in induced regulatory T cells
- (2010) Yohsuke Harada et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Smad2 and Smad3 Are Redundantly Essential for the TGF- -Mediated Regulation of Regulatory T Plasticity and Th1 Development
- (2010) T. Takimoto et al. JOURNAL OF IMMUNOLOGY
- Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
- (2010) Ye Zheng et al. NATURE
- Control of the differentiation of regulatory T cells and TH17 cells by the DNA-binding inhibitor Id3
- (2010) Takashi Maruyama et al. NATURE IMMUNOLOGY
- Effector T cell plasticity: flexibility in the face of changing circumstances
- (2010) Kenneth M Murphy et al. NATURE IMMUNOLOGY
- Control of Regulatory T Cell Lineage Commitment and Maintenance
- (2009) Steven Z. Josefowicz et al. IMMUNITY
- Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo
- (2009) Xuyu Zhou et al. NATURE IMMUNOLOGY
- Regulatory T Cells and Immune Tolerance
- (2008) Shimon Sakaguchi et al. CELL
- Molecular Antagonism and Plasticity of Regulatory and Inflammatory T Cell Programs
- (2008) Xuexian O. Yang et al. IMMUNITY
- STAT6 Inhibits TGF-β1-mediated Foxp3 Induction through Direct Binding to theFoxp3Promoter, Which Is Reverted by Retinoic Acid Receptor
- (2008) Hiromi Takaki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Foxp3 Inhibits RORγt-mediatedIL-17AmRNA Transcription through Direct Interaction with RORγt
- (2008) Kenji Ichiyama et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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