标题
Vitamin C Facilitates Demethylation of theFoxp3Enhancer in a Tet-Dependent Manner
作者
关键词
-
出版物
JOURNAL OF IMMUNOLOGY
Volume 196, Issue 5, Pages 2119-2131
出版商
The American Association of Immunologists
发表日期
2016-01-30
DOI
10.4049/jimmunol.1502352
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Regulation of the Epigenome by Vitamin C
- (2015) Juan I. Young et al. Annual Review of Nutrition
- Hydrogen Sulfide Promotes Tet1- and Tet2-Mediated Foxp3 Demethylation to Drive Regulatory T Cell Differentiation and Maintain Immune Homeostasis
- (2015) Ruili Yang et al. IMMUNITY
- Protein Hydroxylation Catalyzed by 2-Oxoglutarate-dependent Oxygenases
- (2015) Suzana Markolovic et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TET1 is a tumor suppressor of hematopoietic malignancy
- (2015) Luisa Cimmino et al. NATURE IMMUNOLOGY
- Development of a unique epigenetic signature during in vivo Th17 differentiation
- (2015) Bi-Huei Yang et al. NUCLEIC ACIDS RESEARCH
- Epigenetic and transcriptional control of Foxp3+ regulatory T cells
- (2015) Jochen Huehn et al. SEMINARS IN IMMUNOLOGY
- Down-regulation of Tet2 prevents TSDR demethylation in IL2 deficient regulatory T cells
- (2014) Varun Sasidharan Nair et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Function of a Foxp3 cis -Element in Protecting Regulatory T Cell Identity
- (2014) Xudong Li et al. CELL
- Control of the Inheritance of Regulatory T Cell Identity by a cis Element in the Foxp3 Locus
- (2014) Yongqiang Feng et al. CELL
- Hypomethylation at the Regulatory T Cell–Specific Demethylated Region in CD25hiT Cells Is Decoupled from FOXP3 Expression at the Inflamed Site in Childhood Arthritis
- (2014) David Bending et al. JOURNAL OF IMMUNOLOGY
- Ascorbate-induced generation of 5-hydroxymethylcytosine is unaffected by varying levels of iron and 2-oxoglutarate
- (2013) Kevin M. Dickson et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Small molecules enable OCT4-mediated direct reprogramming into expandable human neural stem cells
- (2013) Saiyong Zhu et al. CELL RESEARCH
- Development and Maintenance of Regulatory T cells
- (2013) Naganari Ohkura et al. IMMUNITY
- Ascorbate Induces Ten-Eleven Translocation (Tet) Methylcytosine Dioxygenase-mediated Generation of 5-Hydroxymethylcytosine
- (2013) Emily A. Minor et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Active Demethylation of the Foxp3 Locus Leads to the Generation of Stable Regulatory T Cells within the Thymus
- (2013) A. Toker et al. JOURNAL OF IMMUNOLOGY
- Ascorbic Acid Enhances Tet-Mediated 5-Methylcytosine Oxidation and Promotes DNA Demethylation in Mammals
- (2013) Ruichuan Yin et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- TET enzymes, TDG and the dynamics of DNA demethylation
- (2013) Rahul M. Kohli et al. NATURE
- Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells
- (2013) Kathryn Blaschke et al. NATURE
- Regulatory T cells: recommendations to simplify the nomenclature
- (2013) Abul K Abbas et al. NATURE IMMUNOLOGY
- TETonic shift: biological roles of TET proteins in DNA demethylation and transcription
- (2013) William A. Pastor et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Regulatory T-Cell Therapy in Transplantation: Moving to the Clinic
- (2013) Q. Tang et al. Cold Spring Harbor Perspectives in Medicine
- Plasticity of Foxp3+ T Cells Reflects Promiscuous Foxp3 Expression in Conventional T Cells but Not Reprogramming of Regulatory T Cells
- (2012) Takahisa Miyao et al. IMMUNITY
- Interleukin-2 Inhibits Germinal Center Formation by Limiting T Follicular Helper Cell Differentiation
- (2012) André Ballesteros-Tato et al. IMMUNITY
- T Cell Receptor Stimulation-Induced Epigenetic Changes and Foxp3 Expression Are Independent and Complementary Events Required for Treg Cell Development
- (2012) Naganari Ohkura et al. IMMUNITY
- STAT5 Protein Negatively Regulates T Follicular Helper (Tfh) Cell Generation and Function
- (2012) Roza I. Nurieva et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- STAT5 is a potent negative regulator of TFHcell differentiation
- (2012) Robert J. Johnston et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation
- (2012) Hideharu Hashimoto et al. NUCLEIC ACIDS RESEARCH
- The Analysis of Vitamin C Concentration in Organs ofGulo-/-Mice Upon Vitamin C Withdrawal
- (2012) Hyemin Kim et al. Immune Network
- TET2 Inactivation Results in Pleiotropic Hematopoietic Abnormalities in Mouse and Is a Recurrent Event during Human Lymphomagenesis
- (2011) Cyril Quivoron et al. CANCER CELL
- Tet2 Loss Leads to Increased Hematopoietic Stem Cell Self-Renewal and Myeloid Transformation
- (2011) Kelly Moran-Crusio et al. CANCER CELL
- Intestinal Tolerance Requires Gut Homing and Expansion of FoxP3+ Regulatory T Cells in the Lamina Propria
- (2011) Usriansyah Hadis et al. IMMUNITY
- A Requisite Role for Induced Regulatory T Cells in Tolerance Based on Expanding Antigen Receptor Diversity
- (2011) Dipica Haribhai et al. IMMUNITY
- Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia
- (2011) Víctor Quesada et al. NATURE GENETICS
- Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA
- (2011) Y.-F. He et al. SCIENCE
- Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine
- (2011) S. Ito et al. SCIENCE
- Regulatory T cell plasticity: beyond the controversies
- (2011) Shohei Hori TRENDS IN IMMUNOLOGY
- Vitamin C distribution and retention in the mouse brain
- (2010) Fiona E. Harrison et al. BRAIN RESEARCH
- Prolyl 4-hydroxylase
- (2010) Kelly L. Gorres et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Isolation of intact genomic DNA from FOXP3-sorted human regulatory T cells for epigenetic analyses
- (2010) Leo Hansmann et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
- (2010) Myunggon Ko et al. NATURE
- Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
- (2010) Ye Zheng et al. NATURE
- Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
- (2010) Shinsuke Ito et al. NATURE
- Genomic definition of multiple ex vivo regulatory T cell subphenotypes
- (2010) M. Feuerer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Stability of the Regulatory T Cell Lineage in Vivo
- (2010) Y. P. Rubtsov et al. SCIENCE
- Genetic variation in sodium-dependent ascorbic acid transporters and risk of gastric cancer in Poland
- (2009) Margaret E. Wright et al. EUROPEAN JOURNAL OF CANCER
- A Central Role for Induced Regulatory T Cells in Tolerance Induction in Experimental Colitis
- (2009) D. Haribhai et al. JOURNAL OF IMMUNOLOGY
- Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo
- (2009) Xuyu Zhou et al. NATURE IMMUNOLOGY
- Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
- (2009) M. Tahiliani et al. SCIENCE
- TGF‐β‐induced Foxp3+regulatory T cells rescue scurfy mice
- (2008) Eva N. Huter et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- DNA methylation controls Foxp3 gene expression
- (2008) Julia K. Polansky et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Adaptive Foxp3+ Regulatory T Cell-Dependent and -Independent Control of Allergic Inflammation
- (2008) Maria A. Curotto de Lafaille et al. IMMUNITY
- Polymorphisms in the Estrogen Receptor 1 and Vitamin C and Matrix Metalloproteinase Gene Families Are Associated with Susceptibility to Lymphoma
- (2008) Christine F. Skibola et al. PLoS One
- Regulatory T Cells: Mechanisms of Differentiation and Function
- (2007) Steven Z. Josefowicz et al. Annual Review of Immunology
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started