Pink1 interacts with α-synuclein and abrogates α-synuclein-induced neurotoxicity by activating autophagy

Cognitive Impairment Associated with Parkinson's Disease: Role of Mitochondria

(2016) Nihar R. Das et al.   Current Neuropharmacology

Interaction of α-synuclein with biomembranes in Parkinson's disease —role of cardiolipin

(2016) Stephanie Ghio et al.   PROGRESS IN LIPID RESEARCH

α-Synuclein binds to TOM20 and inhibits mitochondrial protein import in Parkinson’s disease

(2016) Roberto Di Maio et al.   Science Translational Medicine

Piperine induces autophagy by enhancing protein phosphotase 2A activity in a rotenone-induced Parkinson’s disease model

(2016) Jia Liu et al.   Oncotarget

The Interplay Between Respiratory Supercomplexes and ROS in Aging

(2015) Maria Luisa Genova et al.   ANTIOXIDANTS & REDOX SIGNALING

Physiological and Pathological Roles of the Mitochondrial Permeability Transition Pore in the Heart

(2015) Jennifer Q. Kwong et al.   Cell Metabolism

Parkinson's disease

(2015) Lorraine V Kalia et al.   LANCET

The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy

(2015) Jin-Mi Heo et al.   MOLECULAR CELL

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

(2015) Michael Lazarou et al.   NATURE

Pathogenesis of Parkinson disease—the gut–brain axis and environmental factors

(2015) Lisa Klingelhoefer et al.   Nature Reviews Neurology

The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease

(2015) Alicia M. Pickrell et al.   NEURON

The Parkinson Disease Mitochondrial Hypothesis

(2015) Sandra Franco-Iborra et al.   NEUROSCIENTIST

Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65

(2014) Agne Kazlauskaite et al.   BIOCHEMICAL JOURNAL

Potentiation of neurotoxicity in double-mutant mice with Pink1 ablation and A53T-SNCA overexpression

(2014) Suzana Gispert et al.   HUMAN MOLECULAR GENETICS

PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity

(2014) Lesley A. Kane et al.   JOURNAL OF CELL BIOLOGY

Ubiquitin is phosphorylated by PINK1 to activate parkin

(2014) Fumika Koyano et al.   NATURE

Alpha-synuclein-induced neurodegeneration is exacerbated in PINK1 knockout mice

(2014) Marusela Oliveras-Salvá et al.   NEUROBIOLOGY OF AGING

An uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore

(2014) K. N. Alavian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

α-Synuclein and Mitochondrial Dysfunction in Parkinson’s Disease

(2013) Stephen Mullin et al.   MOLECULAR NEUROBIOLOGY

The genetics of Parkinson's disease: Progress and therapeutic implications

(2013) Andrew B. Singleton et al.   MOVEMENT DISORDERS

α-Synuclein and Mitochondria: Partners in Crime?

(2013) Ken Nakamura   Neurotherapeutics

Expression of Pink1 with α-synuclein in the dopaminergic neurons of Drosophila leads to increases in both lifespan and healthspan

(2012) A.M. Todd et al.   GENETICS AND MOLECULAR RESEARCH

α-Synuclein overexpression impairs mitochondrial function by associating with adenylate translocator

(2011) Yuangang Zhu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

PINK1-linked parkinsonism is associated with Lewy body pathology

(2010) Lluís Samaranch et al.   BRAIN

Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1

(2010) Frits Kamp et al.   EMBO JOURNAL

α-Synuclein Transgenic Mice Reveal Compensatory Increases in Parkinson's Disease-Associated Proteins DJ-1 and Parkin and Have Enhanced α-Synuclein and PINK1 Levels After Rotenone Treatment

(2010) Sonia George et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

5-Bromotetrandrine enhances the sensitivity of doxorubicin-induced apoptosis in intrinsic resistant human hepatic cancer Bel7402 cells

(2009) Xiao Dong Liu et al.   CANCER LETTERS

Pink1 suppresses α-synuclein-induced phenotypes in a Drosophila model of Parkinson’s disease

(2008) Amy M. Todd et al.   GENOME