The role of MAP2 kinases and p38 kinase in acute murine liver injury models

Targeting p38 or MK2 Enhances the Anti-Leukemic Activity of Smac-Mimetics

(2016) Najoua Lalaoui et al.   CANCER CELL

Combined Activities of JNK1 and JNK2 in Hepatocytes Protect Against Toxic Liver Injury

(2016) Francisco Javier Cubero et al.   GASTROENTEROLOGY

c-Jun N-terminal kinase mediates mouse liver injury through a novel Sab (SH3BP5)-dependent pathway leading to inactivation of intramitochondrial Src

(2016) Sanda Win et al.   HEPATOLOGY

Sab (Sh3bp5) dependence of JNK mediated inhibition of mitochondrial respiration in palmitic acid induced hepatocyte lipotoxicity

(2015) Sanda Win et al.   JOURNAL OF HEPATOLOGY

Inhibitor of apoptosis signal-regulating kinase 1 protects against acetaminophen-induced liver injury

(2015) Yuchao Xie et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

JNK interaction with Sab mediates ER stress induced inhibition of mitochondrial respiration and cell death

(2014) S Win et al.   Cell Death & Disease

Disruption of Thioredoxin Reductase 1 Protects Mice from Acute Acetaminophen-Induced Hepatotoxicity through Enhanced NRF2 Activity

(2013) Andrew D. Patterson et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Regulation of drug-induced liver injury by signal transduction pathways: critical role of mitochondria

(2013) Derick Han et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Mitogen-activated Protein Kinase Phosphatase (Mkp)-1 Protects Mice against Acetaminophen-induced Hepatic Injury

(2012) Lyn M. Wancket et al.   TOXICOLOGIC PATHOLOGY

c-Jun N-terminal Kinase (JNK)-dependent Acute Liver Injury from Acetaminophen or Tumor Necrosis Factor (TNF) Requires Mitochondrial Sab Protein Expression in Mice

(2011) Sanda Win et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity

(2010) Chieko Saito et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A novel technique for selective NF- B inhibition in Kupffer cells: contrary effects in fulminant hepatitis and ischaemia-reperfusion

(2009) F. Hoffmann et al.   GUT

The liver's dance with death: Two Bcl-2 guardian proteins from the abyss

(2009) Sophie C. Cazanave et al.   HEPATOLOGY

Mcl-1 Degradation during Hepatocyte Lipoapoptosis

(2009) Howard C. Masuoka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mcl-1 Integrates the Opposing Actions of Signaling Pathways That Mediate Survival and Apoptosis

(2009) C. Morel et al.   MOLECULAR AND CELLULAR BIOLOGY

Protective role of c-Jun N-terminal kinase 2 in acetaminophen-induced liver injury

(2008) Mohammed Bourdi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

p38α MAPK inhibits JNK activation and collaborates with IκB kinase 2 to prevent endotoxin-induced liver failure

(2008) Jan Heinrichsdorff et al.   EMBO REPORTS

Deletion of Apoptosis Signal-Regulating Kinase 1 Attenuates Acetaminophen-Induced Liver Injury by Inhibiting c-Jun N-Terminal Kinase Activation

(2008) Hayato Nakagawa et al.   GASTROENTEROLOGY

Role of JNK Translocation to Mitochondria Leading to Inhibition of Mitochondria Bioenergetics in Acetaminophen-induced Liver Injury

(2008) Naoko Hanawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY