Executioner caspases and CAD are essential for mutagenesis induced by TRAIL or vincristine

Onto better TRAILs for cancer treatment

(2016) D de Miguel et al.   CELL DEATH AND DIFFERENTIATION

The caspase-activated DNase: apoptosis and beyond

(2016) Brian D. Larsen et al.   FEBS Journal

TRAIL causes deletions at the HPRT and TK1 loci of clonogenically competent cells

(2016) Mark A. Miles et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Prolonged mitotic arrest induces a caspase-dependent DNA damage response at telomeres that determines cell survival

(2016) Karolina O. Hain et al.   Scientific Reports

DNA Damage in Cancer Therapeutics: A Boon or a Curse?

(2015) Anchit Khanna   CANCER RESEARCH

Limited Mitochondrial Permeabilization Causes DNA Damage and Genomic Instability in the Absence of Cell Death

(2015) Gabriel Ichim et al.   MOLECULAR CELL

Caspase-3 Promotes Genetic Instability and Carcinogenesis

(2015) Xinjian Liu et al.   MOLECULAR CELL

Inhibition of Bcl-2 or IAP proteins does not provoke mutations in surviving cells

(2015) Tanmay M. Shekhar et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

An Inducible Lentiviral Guide RNA Platform Enables the Identification of Tumor-Essential Genes and Tumor-Promoting Mutations In Vivo

(2015) Brandon J. Aubrey et al.   Cell Reports

Genetic variation as a modifier of association between therapeutic exposure and subsequent malignant neoplasms in cancer survivors

(2014) Smita Bhatia   CANCER

Getting TRAIL back on track for cancer therapy

(2014) J Lemke et al.   CELL DEATH AND DIFFERENTIATION

Targeting Microtubules by Natural Agents for Cancer Therapy

(2014) E. Mukhtar et al.   MOLECULAR CANCER THERAPEUTICS

Endonuclease G initiates DNA rearrangements at the MLL breakpoint cluster upon replication stress

(2014) B Gole et al.   ONCOGENE

New roles for old enzymes: killer caspases as the engine of cell behavior changes

(2014) Patrick F. Connolly et al.   Frontiers in Physiology

Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy

(2013) Peter E. Czabotar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Yeast techniques for modeling drugs targeting Bcl-2 and caspase family members

(2013) T E Beaumont et al.   Cell Death & Disease

DNA damage-induced cell death: From specific DNA lesions to the DNA damage response and apoptosis

(2012) Wynand P. Roos et al.   CANCER LETTERS

The central role of initiator caspase-9 in apoptosis signal transduction and the regulation of its activation and activity on the apoptosome

(2012) Maximilian L. Würstle et al.   EXPERIMENTAL CELL RESEARCH

A new way of measuring apoptosis by absolute quantitation of inter-nucleosomally fragmented genomic DNA

(2012) David J. Hooker et al.   NUCLEIC ACIDS RESEARCH

Caspase-3 activation as a bifurcation point between plasticity and cell death

(2012) Shikha Snigdha et al.   Neuroscience Bulletin

Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction

(2011) James D. Orth et al.   MOLECULAR BIOLOGY OF THE CELL

Mitotic catastrophe: a mechanism for avoiding genomic instability

(2011) Ilio Vitale et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Next-Generation Sequencing of Apoptotic DNA Breakpoints Reveals Association with Actively Transcribed Genes and Gene Translocations

(2011) Melissa J. Fullwood et al.   PLoS One

The BH3 Mimetic ABT-737 Induces Cancer Cell Senescence

(2010) Jin H. Song et al.   CANCER RESEARCH

TRAIL treatment provokes mutations in surviving cells

(2010) M M Lovric et al.   ONCOGENE

Caspase 3/caspase-activated DNase promote cell differentiation by inducing DNA strand breaks

(2010) B. D. Larsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The major apoptotic endonuclease DFF40/CAD is a deoxyribose-specific and double-strand-specific enzyme

(2008) Jakub Hanus et al.   APOPTOSIS

Death through a tragedy: mitotic catastrophe

(2008) H Vakifahmetoglu et al.   CELL DEATH AND DIFFERENTIATION

Roles of the Major Apoptotic Nuclease-DNA Fragmentation Factor-in Biology and Disease

(2008) P. Widlak et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Trapping of human DNA topoisomerase I by DNA structures mimicking intermediates of DNA repair

(2008) Natalia Lebedeva et al.   IUBMB LIFE

Topoisomerase I Requirement for Death Receptor-induced Apoptotic Nuclear Fission

(2008) Olivier Sordet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Death Receptor-Induced Activation of the Chk2- and Histone H2AX-Associated DNA Damage Response Pathways

(2008) S. Solier et al.   MOLECULAR AND CELLULAR BIOLOGY

 -H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin

(2008) A. Kinner et al.   NUCLEIC ACIDS RESEARCH

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY