Endonuclease G initiates DNA rearrangements at the MLL breakpoint cluster upon replication stress

Identification of Early Replicating Fragile Sites that Contribute to Genome Instability

(2013) Jacqueline H. Barlow et al.   CELL

The MLL recombinome of acute leukemias in 2013

(2013) C Meyer et al.   LEUKEMIA

Mouse embryonic stem cells undergo charontosis, a novel programmed cell death pathway dependent upon cathepsins, p53, and EndoG, in response to etoposide treatment

(2013) Elisia D. Tichy et al.   Stem Cell Research

CHIP has a protective role against oxidative stress-induced cell death through specific regulation of Endonuclease G

(2013) J S Lee et al.   Cell Death & Disease

Deficiency in Mammalian Histone H2B Ubiquitin Ligase Bre1 (Rnf20/Rnf40) Leads to Replication Stress and Chromosomal Instability

(2012) S. B. Chernikova et al.   CANCER RESEARCH

Rearrangement of the Myeloid/Lymphoid Leukemia Gene in Therapy-Related Myelodysplastic Syndrome in Patients Previously Treated with Agents Targeting DNA Topoisomerase II

(2012) Eman Mosad et al.   ONCOLOGY

Secondary Leukemia Associated with the Anti-Cancer Agent, Etoposide, a Topoisomerase II Inhibitor

(2012) Sachiko Ezoe   International Journal of Environmental Research and Public Health

Therapy-related acute lymphoblastic leukemia is more frequent than previously recognized and has a poor prognosis

(2011) Amal Abdulwahab et al.   CANCER

The cancer burden in the United Kingdom in 2007 due to radiotherapy

(2011) Jacob Maddams et al.   INTERNATIONAL JOURNAL OF CANCER

Endonuclease G interacts with histone H2B and DNA topoisomerase II alpha during apoptosis

(2011) Miroslav Vařecha et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Failure of Origin Activation in Response to Fork Stalling Leads to Chromosomal Instability at Fragile Sites

(2011) Efrat Ozeri-Galai et al.   MOLECULAR CELL

Requirement of ATM-Dependent Monoubiquitylation of Histone H2B for Timely Repair of DNA Double-Strand Breaks

(2011) Lilach Moyal et al.   MOLECULAR CELL

Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction

(2011) Beat Fierz et al.   Nature Chemical Biology

NF-κB regulates DNA double-strand break repair in conjunction with BRCA1–CtIP complexes

(2011) Meta Volcic et al.   NUCLEIC ACIDS RESEARCH

Loss of ATM positively regulates the expression of hypoxia inducible factor 1 (HIF-1) through oxidative stress: Role in the physiopathology of the disease

(2010) Marielle Ousset et al.   CELL CYCLE

A Distinctive DNA Damage Response in Human Hematopoietic Stem Cells Reveals an Apoptosis-Independent Role for p53 in Self-Renewal

(2010) Michael Milyavsky et al.   Cell Stem Cell

Role of endonuclease G in senescence-associated cell death of human endothelial cells

(2010) Thomas Diener et al.   EXPERIMENTAL GERONTOLOGY

Apoptosis of leukocytes triggered by acute DNA damage promotes lymphoma formation

(2010) V. Labi et al.   GENES & DEVELOPMENT

Endonuclease G plays a role in immunoglobulin class switch DNA recombination by introducing double-strand breaks in switch regions

(2010) Hong Zan et al.   MOLECULAR IMMUNOLOGY

ATM Modulates the Loading of Recombination Proteins onto a Chromosomal Translocation Breakpoint Hotspot

(2010) Jiying Sun et al.   PLoS One

ATR: a master conductor of cellular responses to DNA replication stress

(2010) Rachel Litman Flynn et al.   TRENDS IN BIOCHEMICAL SCIENCES

ARTEMIS Nuclease Facilitates Apoptotic Chromatin Cleavage

(2009) S. Britton et al.   CANCER RESEARCH

Complex human chromosomal and genomic rearrangements

(2009) Feng Zhang et al.   TRENDS IN GENETICS

Biologic features and treatment outcome of secondary acute lymphoblastic leukemia—a review of 101 cases

(2008) R. Shivakumar et al.   ANNALS OF ONCOLOGY

Etoposide-initiatedMLLrearrangements detected at high frequency in human primitive hematopoietic stem cells within vitroandin vivolong-term repopulating potential

(2008) Jolanta Libura et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Histone Ubiquitination Associates with BRCA1-Dependent DNA Damage Response

(2008) J. Wu et al.   MOLECULAR AND CELLULAR BIOLOGY