Article
Multidisciplinary Sciences
Laura Pirkola, Johan Dicksved, Jussi Loponen, Ingela Marklinder, Roger Andersson
Summary: This study investigated the effect of two different microbial compositions on the in vitro fermentation of oat, rye, and wheat breads. The fermentation outcomes were found to be influenced by the microbiota composition and the source of dietary fiber.
SCIENTIFIC REPORTS
(2023)
Article
Agriculture, Dairy & Animal Science
Mohan Qiu, Junqing Hu, Han Peng, Bo Li, Jingliang Xu, Xiaoyan Song, Chunlin Yu, Zengrong Zhang, Xiaogang Du, Guixian Bu, Anqi Huang, Xingfa Han, Xianyin Zeng, Chaowu Yang, Fanli Kong
Summary: The dietary fiber level has a significant impact on the cecal microbiota in broilers, promoting microbiota diversity and altering microbial functions. This study highlights the potential benefits of dietary fiber level in poultry production.
Article
Microbiology
Thaisa M. Cantu-Jungles, Nuseybe Bulut, Eponine Chambry, Andrea Ruthes, Marcello Iacomini, Ali Keshavarzian, Timothy A. Johnson, Bruce R. Hamaker
Summary: The study suggests that high-specificity dietary fibers result in more similar responses in gut microbiota, while low-specificity dietary fibers lead to different responses among subjects. High-specificity fibers can promote targeted and predictable microbial shifts in the gut.
Review
Immunology
Ruiqi Hu, Shuwei Li, Hui Diao, Chongbo Huang, Jiayou Yan, Xiaolan Wei, Mengjia Zhou, Peng He, Tianwei Wang, Hongsen Fu, Chengbo Zhong, Chi Mao, Yongsheng Wang, Shengyao Kuang, Wenjie Tang
Summary: Intestinal health is essential for overall animal health and influences production efficiency in animal production systems. Dietary fiber maintains normal intestinal function through microbial fermentation. Short-chain fatty acids, the main metabolites of microbial fermentation, provide energy for intestinal cells and have immunomodulatory effects. Understanding the role of dietary fiber in modulating gut microbiota and its effects on intestinal health is crucial.
FRONTIERS IN IMMUNOLOGY
(2023)
Review
Microbiology
Changxia Yu, Qin Dong, Mingjie Chen, Ruihua Zhao, Lei Zha, Yan Zhao, Mengke Zhang, Baosheng Zhang, Aimin Ma
Summary: This review summarizes the preparation and modification methods, degradation and metabolism in the intestine, impact on gut microbiota community, and beneficial effects on host health of mushroom dietary fiber. It aims to provide theoretical guidance and fresh perspective for the prebiotic application of mushroom dietary fiber in the development of new functional foods and drugs.
Article
Nutrition & Dietetics
Kia Nohr Iversen, Johan Dicksved, Camille Zoki, Rikard Fristedt, Erik A. Pelve, Maud Langton, Rikard Landberg
Summary: Consumption of whole grain and cereal fiber is inversely associated with body weight and obesity. Intake of high fiber rye foods can improve gut microbiota composition and reduce inflammation.
Article
Biochemistry & Molecular Biology
Xincheng Wu, Xiaojun Huang, Wanning Ma, Mingzhi Li, Jiajia Wen, Chunhua Chen, Liandi Liu, Shaoping Nie
Summary: This study compared the intestinal immunomodulatory mechanisms of nine representative bioactive polysaccharides. The results revealed that these polysaccharides promote intestinal immunity through different ways, such as alleviating immune suppression in intestinal mucosal T cells, improving the intestinal microenvironment, promoting the colonization of beneficial bacteria, inhibiting the colonization of harmful bacteria, and alleviating the accumulation of certain metabolites in the large intestine. These findings provide a guideline for the development of superior intestinal immunomodulatory polysaccharides.
Review
Food Science & Technology
Pan Yang, Jinbiao Zhao
Summary: Dietary fibers play a crucial role in promoting intestinal health by modulating gut microbiota and SCFA production. However, different types of dietary fibers from edible sources may have divergent impacts on gut health, energy metabolism, and microbial composition. More attention should be focused on the varying responses of different dietary fibers intake on host metabolism and health.
FOOD SCIENCE & NUTRITION
(2021)
Article
Nutrition & Dietetics
Laura Sinisterra-Loaiza, Patricia Alonso-Lovera, Alejandra Cardelle-Cobas, Jose Manuel Miranda, Beatriz I. Vazquez, Alberto Cepeda
Summary: Various studies have found that specific groups or dietary compounds play a role in the onset and progression of obesity, and gut microbiota serves as a mediator between these compounds and the associated inflammation. This study aimed to evaluate the dietary intake of overweight, obese, and normal-weight individuals and analyze their gut microbiota profile in relation to changes in Body Mass Index (BMI) and diet. The results showed significant differences in fiber and monounsaturated fatty acids (MUFAs) intake among different BMI groups, with better intake adequacy observed in the normal-weight group. The analysis of gut microbiota revealed distinct microbial composition in overweight and obese individuals compared to normal-weight individuals, with specific genera identified as biomarkers for each group.
Article
Food Science & Technology
Ying Hui Lee, Pazhanichamy Kalailingam, Jan A. Delcour, Vincenzo Fogliano, Thirumaran Thanabalu
Summary: This study examines the effect of an olive-derived antioxidant dietary fiber (OADF) on relieving symptoms of atopic dermatitis (AD) and its modulation of gut microbiota. The results show that OADF supplementation significantly improves AD-like symptoms and restores the altered gut microbiota composition in AD mice. OADF also influences cytokine profile and butyrate production, which are associated with AD-associated immune response.
MOLECULAR NUTRITION & FOOD RESEARCH
(2023)
Article
Immunology
Dengfeng Xu, Meiyuan Feng, YiFang Chu, Shaokang Wang, Varsha Shete, Kieran M. Tuohy, Feng Liu, Xirui Zhou, Alison Kamil, Da Pan, Hechun Liu, Xian Yang, Chao Yang, Baoli Zhu, Na Lv, Qian Xiong, Xin Wang, Jianqin Sun, Guiju Sun, Yuexin Yang
Summary: Oats consumption is beneficial for lipid modulation, leading to significant reductions in TC and LDL-C levels. Oats also have a positive impact on gut microbiome, promoting beneficial bacteria and prebiotic effects.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Microbiology
Jori Fuhren, Markus Schwalbe, Jos Boekhorst, Christiane Rosch, Henk A. Schols, Michiel Kleerebezem
Summary: The study found that different levels of calcium phosphate can affect the regulation effects of prebiotics on the intestinal microbiota, while inulin and GOS can modulate the gut microbiota in a similar manner, strongly depending on the level of dietary calcium phosphate.
Article
Nutrition & Dietetics
Laure Meiller, Valerie Sauvinet, Anne-Esther Breyton, Harimalala Ranaivo, Christelle Machon, Anne Mialon, Alexandra Meynier, Stephan C. Bischoff, Jens Walter, Audrey M. Neyrinck, Martine Laville, Nathalie M. Delzenne, Sophie Vinoy, Julie-Anne Nazare
Summary: This pilot study aimed to analyze the kinetics of C-13-labeled gut-derived metabolites from C-13-labeled wheat bran in breath, plasma, and stools. The study found differential fermentation profiles among subjects and identified distinct excretion patterns of gases in high-CH4 producers compared to low-CH4 producers. The study also revealed different kinetics of C-13-labelled short-chain fatty acids in plasma.
EUROPEAN JOURNAL OF NUTRITION
(2023)
Article
Nutrition & Dietetics
Marta Calatayud, Pieter Van den Abbeele, Jonas Ghyselinck, Massimo Marzorati, Eric Rohs, Anne Birkett
Summary: Human gut microbiota plays a crucial role in human health, with diet being one of the key factors that modulates the gut microbial ecosystem. Various dietary components such as fiber, fat, proteins, and micronutrients can shape microbial activity and structure. Research has shown that whole grain cereals have a similar effect on gut microbiota modulation, inducing the production of acetate and butyrate as well as increasing bifidobacteria levels.
FRONTIERS IN NUTRITION
(2021)
Review
Food Science & Technology
Bingbing Guo, Jingyi Zhang, Weihao Zhang, Feng Chen, Bin Liu
Summary: This comprehensive review explores the production of short chain fatty acids (SCFAs) by gut microbiota, their transportation through the gut-brain axis, and the potential mechanisms by which they influence age-related neurodegenerative disorders. The review also discusses the importance of dietary fiber sources and the challenges associated with harnessing dietary-derived SCFAs as promoters of neurological health in elderly individuals.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Agriculture, Multidisciplinary
Parv Nayak, Kalpana Rayaguru, Sandrayee Brahma, Winny Routray, Sanjaya Kumar Dash
Summary: The study found that the optimal method for isolating starch from mango kernels involved a solid-to-water ratio of 1:3 and centrifugation at a frequency of 3 times, resulting in a starch yield of 48.43% ± 1.08% and purity of 76.46% ± 0.83%. The chemically isolated starch exhibited higher paste clarity and better color attributes compared to the starch obtained through centrifugation. Both starches showed good functional, structural, and thermal properties, making them suitable for various applications in the food and non-food industries.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2022)
Correction
Ecology
Rafael R. Segura Munoz, Sara Mantz, Ines Martinez, Fuyong Li, Robert J. Schmaltz, Nicholas A. Pudlo, Karthik Urs, Eric C. Martens, Jens Walter, Amanda E. Ramer-Tait
Article
Immunology
Diana Chiang, Tanis C. Dingle, Sara Belga, Dima Kabbani, Rahima A. Bhanji, Jens Walter, Juan G. Abraldes, Carlos Cervera
Summary: VRE colonization in liver transplant patients is associated with increased risk of early AKI, clinically significant infections, and a trend toward increased mortality at 2 years.
TRANSPLANT INFECTIOUS DISEASE
(2022)
Article
Multidisciplinary Sciences
Harimalala Ranaivo, Zhengxiao Zhang, Maud Alligier, Laurie Van den Berghe, Monique Sothier, Stephanie Lambert-Porcheron, Nathalie Feugier, Charlotte Cuerq, Christelle Machon, Audrey M. Neyrinck, Benjamin Seethaler, Julie Rodriguez, Martin Roumain, Giulio G. Muccioli, Veronique Maquet, Martine Laville, Stephan C. Bischoff, Jens Walter, Nathalie M. Delzenne, Julie-Anne Nazare
Summary: This study investigated the effects of chitin-glucan on participants at cardiometabolic risk, showing improvements in postprandial glycemic response and changes in gut microbiota composition. Compared to the control group, CG supplementation had a positive impact, particularly in subjects with higher exhaled hydrogen levels.
SCIENTIFIC REPORTS
(2022)
Article
Microbiology
Edward C. Deehan, Zhengxiao Zhang, Alessandra Riva, Anissa M. Armet, Maria Elisa Perez-Munoz, Nguyen K. Nguyen, Jacqueline A. Krysa, Benjamin Seethaler, Yuan-Yuan Zhao, Janis Cole, Fuyong Li, Bela Hausmann, Andreas Spittler, Julie-Anne Nazare, Nathalie M. Delzenne, Jonathan M. Curtis, Wendy Wismer, Spencer D. Proctor, Jeffrey A. Bakal, Stephan C. Bischoff, Dan Knights, Catherine J. Field, David Berry, Carla M. Prado, Jens Walter
Summary: This study demonstrates the efficacy of purified dietary fibers when used as supplements and suggests that the satiating effects of AX may be linked to bacterial taxa that ferment the fiber or utilize breakdown products.
Article
Microbiology
Daniel Podlesny, Cesar Arze, Elisabeth Doerner, Sandeep Verma, Sudhir Dutta, Jens Walter, W. Florian Fricke
Summary: SameStr is a bioinformatic tool that can robustly identify shared strains in metagenomic data, providing sufficient specificity and sensitivity to examine strain persistence, transfer, and engraftment. The study identified a persisting core gut microbiota in healthy adults, which has important implications for understanding the contribution of microbiota to chronic diseases.
Article
Gastroenterology & Hepatology
Heather K. Armstrong, Michael Bording-Jorgensen, Deanna M. Santer, Zhengxiao Zhang, Rosica Valcheva, Aja M. Rieger, Justin Sung-Ho Kim, Stephanie I. Dijk, Ramsha Mahmood, Olamide Ogungbola, Juan Jovel, France Moreau, Hayley Gorman, Robyn Dickner, Jeremy Jerasi, Inderdeep K. Mander, Dawson Lafleur, Christopher Cheng, Alexandra Petrova, Terri-Lyn Jeanson, Andrew Mason, Consolato M. Sergi, Arie Levine, Kris Chadee, David Armstrong, Sarah Rauscher, Charles N. Bernstein, Matthew W. Carroll, Hien Q. Huynh, Jens Walter, Karen L. Madsen, Levinus A. Dieleman, Eytan Wine
Summary: Dietary fibers play a role in inflammatory bowel diseases (IBD) by fermenting in the colon, but not all fibers are beneficial. Some IBD patients are intolerant to fiber consumption. This study found that intact b-fructan fibers in certain IBD patients without fermentative microbes can induce gut inflammation by binding to host cell receptors.
Review
Nutrition & Dietetics
Alcides C. de Morais Junior, Raquel M. Schincaglia, Ricardo B. Viana, Anissa M. Armet, Carla M. Prado, Jens Walter, Joao F. Mota
Summary: This study assessed the impact of oats or fi-glucan supplements on lipid profiles through a systematic review and meta-analysis. The results showed that both oats and fi-glucan improved lipid profiles, indicating their potential role in preventing cardiovascular diseases.
CLINICAL NUTRITION ESPEN
(2023)
Article
Biology
Fuyong Li, Xudong Li, Christopher C. Cheng, Dalimil Bujdos, Stephanie Tollenaar, David J. Simpson, Guergana Tasseva, Maria Elisa Perez-Munoz, Steven Frese, Michael G. Ganzle, Jens Walter, Jinshui Zheng
Summary: This study investigates the evolutionary relationship between different strains of Limosilactobacillus reuteri and their vertebrate hosts. It finds that there is a stable and long-term relationship between certain strains of L. reuteri and rodents and birds, while their relationship with other host species is more dynamic and transient. These findings contribute to our understanding of the role of gut microbes in hosts and have implications for microbial-based therapeutics.
Editorial Material
Biochemistry & Molecular Biology
Jens Walter, Fergus Shanahan
Article
Nutrition & Dietetics
Laure Meiller, Valerie Sauvinet, Anne-Esther Breyton, Harimalala Ranaivo, Christelle Machon, Anne Mialon, Alexandra Meynier, Stephan C. Bischoff, Jens Walter, Audrey M. Neyrinck, Martine Laville, Nathalie M. Delzenne, Sophie Vinoy, Julie-Anne Nazare
Summary: This pilot study aimed to analyze the kinetics of C-13-labeled gut-derived metabolites from C-13-labeled wheat bran in breath, plasma, and stools. The study found differential fermentation profiles among subjects and identified distinct excretion patterns of gases in high-CH4 producers compared to low-CH4 producers. The study also revealed different kinetics of C-13-labelled short-chain fatty acids in plasma.
EUROPEAN JOURNAL OF NUTRITION
(2023)
Article
Virology
Ema H. Graham, Wesley A. Tom, Alison C. Neujahr, Michael S. Adamowicz, Jennifer L. Clarke, Joshua R. Herr, Samodha C. Fernando
Summary: This study reveals that the human skin virome is mainly composed of tailed Caudovirales phages that carry auxiliary genes to increase bacterial host fitness through antimicrobial resistance. The virome is associated with auxiliary metabolic genes and antimicrobial resistance genes, which help increase bacterial host fitness.
Article
Microbiology
Hatem Kittana, Joao C. Gomes-Neto, Kari Heck, Anthony F. Juritsch, Jason Sughroue, Yibo Xian, Sara Mantz, Rafael Segura R. Munoz, Liz A. Cody, Robert J. Schmaltz, Christopher L. Anderson, Rodney A. Moxley, Jesse M. Hostetter, Samodha C. Fernando, Jennifer Clarke, Stephen D. Kachman, Clayton E. Cressler, Andrew K. Benson, Jens Walter, Amanda E. Ramer-Tait
Summary: Inflammatory bowel disease (IBD) is associated with an altered gut microbiota composition, including expansion of Proteobacteria. Adherent-invasive Escherichia coli (AIEC) strains are enriched in some IBD patients, and AIEC strains show enhanced pathogenicity compared to non-AIEC strains. AIEC strains cause more severe intestinal inflammation and intracellular survival/replication phenotypes positively correlate with disease. This knowledge can be therapeutically exploited to alleviate intestinal inflammation.
Article
Nutrition & Dietetics
Sarah A. Potgens, Sophie Lecop, Violaine Havelange, Fuyong Li, Audrey M. Neyrinck, Nathalie Neveux, Johan Maertens, Jens Walter, Helene Schoemans, Nathalie M. Delzenne, Laure B. Bindels
Summary: In this study, the researchers investigated the changes in gut microbiota induced by intensive therapy in acute myeloid leukaemia (AML) patients. They found that the therapy temporarily impaired the gut barrier function and led to long-lasting alterations in the composition and metabolic activity of the gut microbiota, which were associated with weight loss.
CLINICAL NUTRITION
(2023)
Article
Mathematical & Computational Biology
Jennifer L. Clarke, Laurel D. Cooper, Monica F. Poelchau, Tanya Z. Berardini, Justin Elser, Andrew D. Farmer, Stephen Ficklin, Sunita Kumari, Marie-Angelique Laporte, Rex T. Nelson, Rie Sadohara, Peter Selby, Anne E. Thessen, Brandon Whitehead, Taner Z. Sen
Summary: In the past few decades, there has been a rapid growth in the number and scope of agricultural genetics, genomics, and breeding databases and resources. The AgBioData Consortium aims to facilitate data management and integration, and a survey conducted among its members showed positive data-sharing practices but no substantial change in ontology use. Recommendations include providing training, further studying metadata sharing, and improving data sharing and ontology use.
DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION
(2023)
