Discovery of potent human lactate dehydrogenase A (LDHA) inhibitors with antiproliferative activity against lung cancer cells: virtual screening and biological evaluation
出版年份 2017 全文链接
标题
Discovery of potent human lactate dehydrogenase A (LDHA) inhibitors with antiproliferative activity against lung cancer cells: virtual screening and biological evaluation
作者
关键词
-
出版物
MedChemComm
Volume 8, Issue 3, Pages 599-605
出版商
Royal Society of Chemistry (RSC)
发表日期
2017-01-14
DOI
10.1039/c6md00670a
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Lactate dehydrogenase inhibitors can reverse inflammation induced changes in colon cancer cells
- (2017) Marcella Manerba et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Discovery of 2-((3-cyanopyridin-2-yl)thio)acetamides as human lactate dehydrogenase A inhibitors to reduce the growth of MG-63 osteosarcoma cells: Virtual screening and biological validation
- (2016) Wei Cui et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition
- (2016) Aaron Boudreau et al. Nature Chemical Biology
- Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice
- (2016) Hans E. Purkey et al. ACS Medicinal Chemistry Letters
- Lactate dehydrogenase 5: An old friend and a new hope in the war on cancer
- (2015) Katarzyna Augoff et al. CANCER LETTERS
- Development of pyruvate dehydrogenase kinase inhibitors in medicinal chemistry with particular emphasis as anticancer agents
- (2015) Shao-Lin Zhang et al. DRUG DISCOVERY TODAY
- Identification of N-acylhydrazone derivatives as novel lactate dehydrogenase A inhibitors
- (2015) Sebastiano Rupiani et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Recent Update on Human Lactate Dehydrogenase Enzyme 5 (hLDH5) Inhibitors: A Promising Approach for Cancer Chemotherapy
- (2015) Reshma Rani et al. JOURNAL OF MEDICINAL CHEMISTRY
- Identification of substituted 3-hydroxy-2-mercaptocyclohex-2-enones as potent inhibitors of human lactate dehydrogenase
- (2014) Peter S. Dragovich et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Targeting Lactate Dehydrogenase-A Inhibits Tumorigenesis and Tumor Progression in Mouse Models of Lung Cancer and Impacts Tumor-Initiating Cells
- (2014) Han Xie et al. Cell Metabolism
- FOXM1 Promotes the Warburg Effect and Pancreatic Cancer Progression via Transactivation of LDHA Expression
- (2014) J. Cui et al. CLINICAL CANCER RESEARCH
- Knockdown of lactate dehydrogenase A suppresses tumor growth and metastasis of human hepatocellular carcinoma
- (2012) Shi L. Sheng et al. FEBS Journal
- Design and Synthesis of Novel Lactate Dehydrogenase A Inhibitors by Fragment-Based Lead Generation
- (2012) Richard A. Ward et al. JOURNAL OF MEDICINAL CHEMISTRY
- LDH-A silencing suppresses breast cancer tumorigenicity through induction of oxidative stress mediated mitochondrial pathway apoptosis
- (2011) Zhi-Yu Wang et al. BREAST CANCER RESEARCH AND TREATMENT
- Discovery ofN-Hydroxyindole-Based Inhibitors of Human Lactate Dehydrogenase Isoform A (LDH-A) as Starvation Agents against Cancer Cells
- (2011) Carlotta Granchi et al. JOURNAL OF MEDICINAL CHEMISTRY
- Interfering with pH regulation in tumours as a therapeutic strategy
- (2011) Dario Neri et al. NATURE REVIEWS DRUG DISCOVERY
- Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
- (2010) A. Le et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now