期刊
CHEMICAL SCIENCE
卷 8, 期 4, 页码 3026-3030出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6sc04522g
关键词
-
资金
- IISER Bhopal
- CSIR
- UGC, New Delhi, India
An unprecedented enantioselective synthesis of 3-substituted benzoxaboroles has been developed. An in situ generated ortho-boronic acid containing chalcone provides the chiral benzoxaboroles via an asymmetric oxa-Michael addition of hydroxyl group attached to the boronic acid triggered by the cinchona alkaloid based chiral amino-squaramide catalysts. In general, good yields with good to excellent enantioselectivities (up to 99%) were obtained. The resulting benzoxaboroles were converted to the corresponding chiral beta-hydroxy ketones without affecting the enantioselectivity.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据