Micro-flow photosynthesis of new dienophiles for inverse-electron-demand Diels–Alder reactions. Potential applications for pretargeted in vivo PET imaging

Applications of Continuous-Flow Photochemistry in Organic Synthesis, Material Science, and Water Treatment

(2016) Dario Cambié et al.   CHEMICAL REVIEWS

Efficient low-cost preparation of trans-cyclooctenes using a simplified flow setup for photoisomerization

(2016) Dennis Svatunek et al.   MONATSHEFTE FUR CHEMIE

A convenient numbering-up strategy for the scale-up of gas–liquid photoredox catalysis in flow

(2016) Yuanhai Su et al.   Reaction Chemistry & Engineering

Improved Metabolic Stability for 18F PET Probes Rapidly Constructed via Tetrazine trans-Cyclooctene Ligation

(2015) Ramajeyam Selvaraj et al.   BIOCONJUGATE CHEMISTRY

18F-Based Pretargeted PET Imaging Based on Bioorthogonal Diels–Alder Click Chemistry

(2015) Jan-Philip Meyer et al.   BIOCONJUGATE CHEMISTRY

Antibody Positron Emission Tomography Imaging in Anticancer Drug Development

(2015) Laetitia E. Lamberts et al.   JOURNAL OF CLINICAL ONCOLOGY

Pretargeted Immuno-PET of Pancreatic Cancer: Overcoming Circulating Antigen and Internalized Antibody to Reduce Radiation Doses

(2015) J. L. Houghton et al.   JOURNAL OF NUCLEAR MEDICINE

Diabody Pretargeting with Click Chemistry In Vivo

(2015) S. M. J. van Duijnhoven et al.   JOURNAL OF NUCLEAR MEDICINE

Feasibility of Affibody-Based Bioorthogonal Chemistry-Mediated Radionuclide Pretargeting

(2015) M. Altai et al.   JOURNAL OF NUCLEAR MEDICINE

Optimization of a Pretargeted Strategy for the PET Imaging of Colorectal Carcinoma via the Modulation of Radioligand Pharmacokinetics

(2015) Brian M. Zeglis et al.   MOLECULAR PHARMACEUTICS

Development of a18F-Labeled Tetrazine with Favorable Pharmacokinetics for Bioorthogonal PET Imaging

(2014) Christoph Denk et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

68Ga chelating bioorthogonal tetrazine polymers for the multistep labeling of cancer biomarkers

(2014) Brandon Nichols et al.   CHEMICAL COMMUNICATIONS

A bioorthogonal 68Ga-labelling strategy for rapid in vivo imaging

(2014) Helen L. Evans et al.   CHEMICAL COMMUNICATIONS

Photochemical Transformations Accelerated in Continuous-Flow Reactors: Basic Concepts and Applications

(2014) Yuanhai Su et al.   CHEMISTRY-A EUROPEAN JOURNAL

Theranostic applications of antibodies in oncology

(2014) Emmy D.G. Fleuren et al.   Molecular Oncology

Trans-Cyclooctene Tag with Improved Properties for Tumor Pretargeting with the Diels–Alder Reaction

(2014) Raffaella Rossin et al.   MOLECULAR PHARMACEUTICS

In vivo evaluation of 18F-labeled TCO for pre-targeted PET imaging in the brain

(2014) Leonie wyffels et al.   NUCLEAR MEDICINE AND BIOLOGY

Conformationally strained trans-cyclooctene with improved stability and excellent reactivity in tetrazine ligation

(2014) Ampofo Darko et al.   Chemical Science

18F-Labeled-Bioorthogonal Liposomes for In Vivo Targeting

(2013) Fabien Emmetiere et al.   BIOCONJUGATE CHEMISTRY

Highly Reactive trans-Cyclooctene Tags with Improved Stability for Diels–Alder Chemistry in Living Systems

(2013) Raffaella Rossin et al.   BIOCONJUGATE CHEMISTRY

The inverse electron demand Diels-Alder click reaction in radiochemistry

(2013) Thomas Reiner et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Development and Evaluation of 18F-TTCO-Cys40-Exendin-4: A PET Probe for Imaging Transplanted Islets

(2013) Z. Wu et al.   JOURNAL OF NUCLEAR MEDICINE

A Pretargeted PET Imaging Strategy Based on Bioorthogonal Diels-Alder Click Chemistry

(2013) B. M. Zeglis et al.   JOURNAL OF NUCLEAR MEDICINE

Diels-Alder Reaction for Tumor Pretargeting: In Vivo Chemistry Can Boost Tumor Radiation Dose Compared with Directly Labeled Antibody

(2013) R. Rossin et al.   JOURNAL OF NUCLEAR MEDICINE

A Magnetic Gram Stain for Bacterial Detection

(2012) Ghyslain Budin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

68Ga-Complex Lipophilicity and the Targeting Property of a Urea-Based PSMA Inhibitor for PET Imaging

(2012) Matthias Eder et al.   BIOCONJUGATE CHEMISTRY

PET imaging with 89Zr: From radiochemistry to the clinic

(2012) Melissa A. Deri et al.   NUCLEAR MEDICINE AND BIOLOGY

Reactive polymer enables efficient in vivo bioorthogonal chemistry

(2012) N. K. Devaraj et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficient18F-Labeling of Synthetic Exendin-4 Analogues for Imaging Beta Cells

(2012) Edmund J. Keliher et al.   ChemistryOpen

Synthesis and In Vivo Imaging of a 18F-Labeled PARP1 Inhibitor Using a Chemically Orthogonal Scavenger-Assisted High-Performance Method

(2011) Thomas Reiner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and Evaluation of a Series of 1,2,4,5-Tetrazines for Bioorthogonal Conjugation

(2011) Mark R. Karver et al.   BIOCONJUGATE CHEMISTRY

Tetrazine-trans-cyclooctene ligation for the rapid construction of integrin αvβ3 targeted PET tracer based on a cyclic RGD peptide

(2011) Ramajeyam Selvaraj et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

In Vivo Chemistry for Pretargeted Tumor Imaging in Live Mice

(2010) Raffaella Rossin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tetrazine–trans-cyclooctene ligation for the rapid construction of 18F labeled probes

(2010) Zibo Li et al.   CHEMICAL COMMUNICATIONS

Fast and Sensitive Pretargeted Labeling of Cancer Cells through a Tetrazine/trans-Cyclooctene Cycloaddition

(2009) Neal K. Devaraj et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Developing new molecular imaging probes for PET

(2009) Kim Serdons et al.   METHODS

Tetrazine-Based Cycloadditions: Application to Pretargeted Live Cell Imaging

(2008) Neal K. Devaraj et al.   BIOCONJUGATE CHEMISTRY

A Photochemical Synthesis of Functionalizedtrans-Cyclooctenes Driven by Metal Complexation

(2008) Maksim Royzen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tetrazine Ligation: Fast Bioconjugation Based on Inverse-Electron-Demand Diels−Alder Reactivity

(2008) Melissa L. Blackman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY