A thiocyanopalladation/carbocyclization transformation identified through enzymatic screening: stereocontrolled tandem C–SCN and C–C bond formation
出版年份 2017 全文链接
标题
A thiocyanopalladation/carbocyclization transformation identified through enzymatic screening: stereocontrolled tandem C–SCN and C–C bond formation
作者
关键词
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出版物
Chemical Science
Volume 8, Issue 12, Pages 8050-8060
出版商
Royal Society of Chemistry (RSC)
发表日期
2017-10-03
DOI
10.1039/c7sc04083k
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Synthesis and Deployment of an Elusive Fluorovinyl Cation Equivalent: Access to Quaternary α-(1′-Fluoro)vinyl Amino Acids as Potential PLP Enzyme Inactivators
- (2017) Christopher D. McCune et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Discovery of Multicomponent Heterogeneous Catalysts via Admixture Screening: PdBiTe Catalysts for Aerobic Oxidative Esterification of Primary Alcohols
- (2017) David S. Mannel et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Practical High-Throughput Experimentation for Chemists
- (2017) Michael Shevlin ACS Medicinal Chemistry Letters
- Regioselective Synthesis of 2-Substituted Indoles from Benzotriazoles and Alkynes by Photoinitiated Denitrogenation
- (2017) Michael Teders et al. ACS Catalysis
- An NAD(P)H-Dependent Artificial Transfer Hydrogenase for Multienzymatic Cascades
- (2016) Yasunori Okamoto et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Nitrile Probes of Electric Field Agree with Independently Measured Fields in Green Fluorescent Protein Even in the Presence of Hydrogen Bonding
- (2016) Joshua D. Slocum et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Non-covalent S⋯O interactions control conformation in a scaffold that disrupts islet amyloid polypeptide fibrillation
- (2016) Hayden Peacock et al. Chemical Science
- One-Pot Cascade Synthesis of Mono- and Disubstituted Piperidines and Pyrrolidines using Carboxylic Acid Reductase (CAR), ω-Transaminase (ω-TA), and Imine Reductase (IRED) Biocatalysts
- (2016) Scott P. France et al. ACS Catalysis
- Miniature high-throughput chemosensing of yield, ee, and absolute configuration from crude reaction mixtures
- (2016) K. W. Bentley et al. Science Advances
- Ruthenium(0)-Catalyzed [4+2] Cycloaddition of Acetylenic Aldehydes with α-Ketols: Convergent Construction of Angucycline Ring Systems
- (2015) Aakarsh Saxena et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Catalytic Decarboxylative Cross-Coupling of Aryl Chlorides and Benzoates without ActivatingorthoSubstituents
- (2015) Jie Tang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes
- (2015) Stuart L. Schreiber et al. CELL
- Recent advances in C–S bond formation via C–H bond functionalization and decarboxylation
- (2015) Chao Shen et al. CHEMICAL SOCIETY REVIEWS
- Rhodium-Catalyzed CS and CN Functionalization of Arenes: Combination of CH Activation and Hypervalent Iodine Chemistry
- (2015) Fen Wang et al. CHEMISTRY-A EUROPEAN JOURNAL
- Diastereoselective Synthesis of Fluorine-Containing Pyrrolizidines via Triphenylcarbenium Tetrafluoroborate-Promoted Carbofluorination of N-3-Arylpropargylpyrrolidine-Tethered Tertiary Allylic Alcohols
- (2015) Ming-Chang P. Yeh et al. JOURNAL OF ORGANIC CHEMISTRY
- Combining a Clostridial Enzyme Exhibiting Unusual Active Site Plasticity with a Remarkably Facile Sigmatropic Rearrangement: Rapid, Stereocontrolled Entry into Densely Functionalized Fluorinated Phosphonates for Chemical Biology
- (2015) Kaushik Panigrahi et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Copper-Catalyzed Intermolecular Trifluoromethylazidation and Trifluoromethylthiocyanation of Allenes: Efficient Access to CF3-Containing Allyl Azides and Thiocyanates
- (2015) Na Zhu et al. ORGANIC LETTERS
- Activation of Aryl Thiocyanates Followed by Aryne Insertion: Access to 1,2-Thiobenzonitriles
- (2015) Martin Pawliczek et al. ORGANIC LETTERS
- Copper-Catalyzed Intermolecular Trifluoromethylthiocyanation of Alkenes: Convenient Access to CF3-Containing Alkyl Thiocyanates
- (2015) Zhaoli Liang et al. ORGANIC LETTERS
- Identifying lead hits in catalyst discovery by screening and deconvoluting complex mixtures of catalyst components
- (2015) Eléna Wolf et al. Chemical Science
- Mini-ISES identifies promising carbafructopyranose-based salens for asymmetric catalysis: Tuning ligand shape via the anomeric effect
- (2015) K. R. Karukurichi et al. Science Advances
- Catalytic Enantioselective 1,3-Dipolar Cycloadditions of Azomethine Ylides for Biology-Oriented Synthesis
- (2014) Rishikesh Narayan et al. ACCOUNTS OF CHEMICAL RESEARCH
- General Platform for Systematic Quantitative Evaluation of Small-Molecule Permeability in Bacteria
- (2014) Tony D. Davis et al. ACS Chemical Biology
- [4+2+2] Cycloaddition catalyzed by a new cationic rhodium–bisphosphine monooxide complex
- (2014) Gino Martin R. Canlas et al. CHEMICAL COMMUNICATIONS
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- (2013) Satsuki Otsuki et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
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- (2013) Linda M. Suen et al. Chemical Science
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- (2012) Amy J. Stafford et al. BIOCHEMISTRY
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- (2012) Hugo Lachance et al. JOURNAL OF MEDICINAL CHEMISTRY
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- (2012) Olivier Jackowski et al. ORGANIC LETTERS
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- (2012) T. K. Hyster et al. SCIENCE
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- (2011) Lin Xu et al. BIOCHEMISTRY
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- (2011) Irina P. Beletskaya et al. CHEMICAL REVIEWS
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- (2011) Aireal D. Jenkins et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Carbon−Sulfur Bond Formation via Iridium-Catalyzed Asymmetric Allylation of Aliphatic Thiols
- (2011) Ning Gao et al. ORGANIC LETTERS
- Neuraminidase Inhibitory Polyketides from the Marine-derived FungusPhoma herbarum
- (2011) Gao Zhang et al. PLANTA MEDICA
- A P,N-Ligand for Palladium-Catalyzed Ammonia Arylation: Coupling of Deactivated Aryl Chlorides, Chemoselective Arylations, and Room Temperature Reactions
- (2010) Rylan J. Lundgren et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- One-Pot Synthesis of Unsymmetrical Diaryl Thioethers by Palladium-Catalyzed Coupling of Two Aryl Bromides and a Thiol Surrogate
- (2010) Manuel A. Fernández-Rodríguez et al. CHEMISTRY-A EUROPEAN JOURNAL
- Recent advances in multicomponent reactions for diversity-oriented synthesis
- (2010) James E. Biggs-Houck et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Privileged scaffolds for library design and drug discovery
- (2010) Matthew E Welsch et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Reaction Discovery Using Microfluidic-Based Multidimensional Screening of Polycyclic Iminium Ethers
- (2010) Jennifer L. Treece et al. JOURNAL OF ORGANIC CHEMISTRY
- The Effects of α-Helical Structure and Cyanylated Cysteine on Each Other
- (2010) Lena Edelstein et al. JOURNAL OF PHYSICAL CHEMISTRY B
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- (2010) Heather A. McMahon et al. Journal of Physical Chemistry Letters
- An Efficient Copper-Catalyzed Carbon−Sulfur Bond Formation Protocol in Water
- (2010) Fang Ke et al. ORGANIC LETTERS
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- (2010) S. Lutz SCIENCE
- Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture
- (2010) C. K. Savile et al. SCIENCE
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- (2010) J. B. Siegel et al. SCIENCE
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- (2009) Michael P. Hay et al. JOURNAL OF MEDICINAL CHEMISTRY
- A General, Efficient, and Functional-Group-Tolerant Catalyst System for the Palladium-Catalyzed Thioetherification of Aryl Bromides and Iodides
- (2009) Manuel A. Fernández-Rodríguez et al. JOURNAL OF ORGANIC CHEMISTRY
- Evolution of a Fourth Generation Catalyst for the Amination and Thioetherification of Aryl Halides
- (2008) John F. Hartwig ACCOUNTS OF CHEMICAL RESEARCH
- A Rationally Designed Aldolase Foldamer
- (2008) Manuel M. Müller et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Electrostatic Fields Near the Active Site of Human Aldose Reductase: 1. New Inhibitors and Vibrational Stark Effect Measurements†
- (2008) Lauren J. Webb et al. BIOCHEMISTRY
- A Cheap Metal for a “Noble” Task: Preparative and Mechanistic Aspects of Cycloisomerization and Cycloaddition Reactions Catalyzed by Low-Valent Iron Complexes
- (2008) Alois Fürstner et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- De Novo Computational Design of Retro-Aldol Enzymes
- (2008) L. Jiang et al. SCIENCE
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