The NADPH oxidase Nox4 has anti-atherosclerotic functions

Vascular oxidative stress, nitric oxide and atherosclerosis

(2014) Huige Li et al.   ATHEROSCLEROSIS

Assessment of Atherosclerosis in Chronic Granulomatous Disease

(2014) Christopher T. Sibley et al.   CIRCULATION

NOX1 deficiency in apolipoprotein E-knockout mice is associated with elevated plasma lipids and enhanced atherosclerosis

(2014) C. G. Sobey et al.   FREE RADICAL RESEARCH

Nox4 NADPH oxidase contributes to smooth muscle cell phenotypes associated with unstable atherosclerotic plaques

(2014) Shaoping Xu et al.   Redox Biology

Reduced Atherosclerotic Burden in Subjects With Genetically Determined Low Oxidative Stress

(2013) Francesco Violi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

NADPH Oxidase 1 Plays a Key Role in Diabetes Mellitus–Accelerated Atherosclerosis

(2013) Stephen P. Gray et al.   CIRCULATION

NADPH oxidase 4 limits bone mass by promoting osteoclastogenesis

(2013) Claudia Goettsch et al.   JOURNAL OF CLINICAL INVESTIGATION

Increased Epidermal Growth Factor–Like Ligands Are Associated With Elevated Vascular Nicotinamide Adenine Dinucleotide Phosphate Oxidase in a Primate Model of Atherosclerosis

(2012) Bojana Stanic et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Nox4 Is a Protective Reactive Oxygen Species Generating Vascular NADPH Oxidase

(2012) Katrin Schröder et al.   CIRCULATION RESEARCH

Role of Nox4 in murine models of kidney disease

(2012) Andrea Babelova et al.   FREE RADICAL BIOLOGY AND MEDICINE

Actions of “antioxidants” in the protection against atherosclerosis

(2012) Maria E. Lönn et al.   FREE RADICAL BIOLOGY AND MEDICINE

NADPH Oxidase 4 Promotes Endothelial Angiogenesis Through Endothelial Nitric Oxide Synthase Activation

(2011) Siobhan M. Craige et al.   CIRCULATION

Nox4 regulates Nrf2 and glutathione redox in cardiomyocytes in vivo

(2011) Alison C. Brewer et al.   FREE RADICAL BIOLOGY AND MEDICINE

Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets

(2011) Grant R. Drummond et al.   NATURE REVIEWS DRUG DISCOVERY

Nox4 is a Novel Inducible Source of Reactive Oxygen Species in Monocytes and Macrophages and Mediates Oxidized Low Density Lipoprotein–Induced Macrophage Death

(2010) Chi Fung Lee et al.   CIRCULATION RESEARCH

Novel Nox homologues in the vasculature: focusing on Nox4 and Nox5

(2010) Augusto C. Montezano et al.   CLINICAL SCIENCE

NADPH oxidases in cardiovascular disease

(2010) Ralf P. Brandes et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nox4-Derived H2O2 Mediates Endoplasmic Reticulum Signaling through Local Ras Activation

(2010) R.-F. Wu et al.   MOLECULAR AND CELLULAR BIOLOGY

NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis

(2010) M. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Partial carotid ligation is a model of acutely induced disturbed flow, leading to rapid endothelial dysfunction and atherosclerosis

(2009) Douglas Nam et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Direct evidence of a role for Nox2 in superoxide production, reduced nitric oxide bioavailability, and early atherosclerotic plaque formation in ApoE−/− mice

(2009) Courtney P. Judkins et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The NADPH oxidase Nox4 restricts the replicative lifespan of human endothelial cells

(2009) Barbara Lener et al.   BIOCHEMICAL JOURNAL

Hereditary Deficiency of gp91 phox Is Associated With Enhanced Arterial Dilatation

(2009) Francesco Violi et al.   CIRCULATION