Barriers to the conduct of randomised clinical trials within all disease areas

Evidence-based clinical practice: Overview of threats to the validity of evidence and how to minimise them

(2016) Silvio Garattini et al.   European Journal of Internal Medicine

Publicly funded practice-oriented clinical trials: of importance for healthcare payers

(2016) Mattias Neyt et al.   Journal of Comparative Effectiveness Research

Clarithromycin for stable coronary heart disease increases all-cause and cardiovascular mortality and cerebrovascular morbidity over 10years in the CLARICOR randomised, blinded clinical trial

(2015) Per Winkel et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Statistical challenges for central monitoring in clinical trials: a review

(2015) Koji Oba   International Journal of Clinical Oncology

Is crowdfunding a viable source of clinical trial research funding?

(2015) Abhinav Sharma et al.   LANCET

In new crowdfunding trend, donors decide fate of clinical trials

(2015) Shraddha Chakradhar   NATURE MEDICINE

The Cooperative Landscape of Multinational Clinical Trials

(2015) David Hsiehchen et al.   PLoS One

Differential Globalization of Industry- and Non-Industry–Sponsored Clinical Trials

(2015) Ignacio Atal et al.   PLoS One

Levels of Alkaline Phosphatase and Bilirubin Are Surrogate End Points of Outcomes of Patients With Primary Biliary Cirrhosis: An International Follow-up Study

(2014) Willem J. Lammers et al.   GASTROENTEROLOGY

Reducing waste from incomplete or unusable reports of biomedical research

(2014) Paul Glasziou et al.   LANCET

Increasing value and reducing waste: addressing inaccessible research

(2014) An-Wen Chan et al.   LANCET

Increasing value and reducing waste in biomedical research regulation and management

(2014) Rustam Al-Shahi Salman et al.   LANCET

How to increase value and reduce waste when research priorities are set

(2014) Iain Chalmers et al.   LANCET

Increasing value and reducing waste in research design, conduct, and analysis

(2014) John P A Ioannidis et al.   LANCET

Outcome Reporting Among Drug Trials Registered in ClinicalTrials.gov

(2013) Florence T. Bourgeois   ANNALS OF INTERNAL MEDICINE

Registration Rates, Adequacy of Registration, and a Comparison of Registered and Published Primary Outcomes in Randomized Controlled Trials Published in Surgery Journals

(2013) Shane Killeen et al.   ANNALS OF SURGERY

What do non-randomized trials offer above and beyond randomized trials?

(2013) Vance W. Berger   Contemporary Clinical Trials

Concern about security and privacy, and perceived control over collection and use of health information are related to withholding of health information from healthcare providers

(2013) Israel T Agaku et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

The fourth age of research

(2013) Jonathan Adams   NATURE

Randomized Clinical Trials — Removing Unnecessary Obstacles

(2013) Christina Reith et al.   NEW ENGLAND JOURNAL OF MEDICINE

Factors influencing clinical trial site selection in Europe: the Survey of Attitudes towards Trial sites in Europe (the SAT-EU Study)

(2013) Marta Gehring et al.   BMJ Open

A European approach to clinical investigator training

(2013) Jean-Marie Boeynaems et al.   Frontiers in Pharmacology

GRADE guidelines: 11. Making an overall rating of confidence in effect estimates for a single outcome and for all outcomes

(2012) Gordon Guyatt et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

The rise of research networks

(2012) Jonathan Adams   NATURE

Typical investigational medicinal products follow relatively uniform regulations in 10 European Clinical Research Infrastructures Network (ECRIN) countries

(2012) Christian Gluud et al.   Trials

Impact assessment of the European Clinical Trials Directive: a longitudinal, prospective, observational study analyzing patterns and trends in clinical drug trial applications submitted since 2001 to regulatory agencies in six EU countries

(2012) Markus Hartmann   Trials

A European perspective - the European clinical research infrastructures network

(2011) J. Demotes-Mainard et al.   ANNALS OF ONCOLOGY

Monitoring the quality of conduct of clinical trials: a survey of current practices

(2011) Briggs W Morrison et al.   Clinical Trials

New FDA Regulation to Improve Safety Reporting in Clinical Trials

(2011) Rachel Behrman Sherman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Harmonisation of ethics committees' practice in 10 European countries

(2009) R Hernandez et al.   JOURNAL OF MEDICAL ETHICS

Avoidable waste in the production and reporting of research evidence

(2009) Iain Chalmers et al.   LANCET

Ethical and Scientific Implications of the Globalization of Clinical Research

(2009) Seth W. Glickman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Norwegian Physicians' Knowledge of and Opinions about Evidence-Based Medicine: Cross-Sectional Study

(2009) Lidziya Vanahel Ulvenes et al.   PLoS One

Sensible approaches for reducing clinical trial costs

(2008) Eric L Eisenstein et al.   Clinical Trials

Specific barriers to the conduct of randomized trials

(2008) Lelia Duley et al.   Clinical Trials