Updates on synthesis and biological activities of 1,3,4-oxadiazole: A review

Novel gold(I) complexes with 5-phenyl-1,3,4-oxadiazole-2-thione and phosphine as potential anticancer and antileishmanial agents

(2017) Joana Darc S. Chaves et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis and anticancer activity of new monastrol analogues bearing 1,3,4-oxadiazole moiety

(2017) Fatma A.F. Ragab et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, structural studies and biological activities of three new 2-(pentadecylthio)-5-aryl-1,3,4-oxadiazoles

(2017) Muhammad Naeem Ahmed et al.   JOURNAL OF MOLECULAR STRUCTURE

Synthesis, characterization and antimicrobial activity of 1,3,4-oxadiazole bearing 1H-benzimidazole derivatives

(2017) Salahuddin et al.   Arabian Journal of Chemistry

Synthesis and bioactivities of 1-aryl-4-hydroxy-1H-pyrrol-2(5H)-one derivatives bearing 1,3,4-oxadiazole moiety

(2017) Pei-Yi Wang et al.   Journal of Saudi Chemical Society

Synthesis and in vitro antiproliferative evaluation of novel nonsymmetrical disulfides bearing 1,3,4-oxadiazole moiety

(2016) Ji-Jun Zhao et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and biological activities of novel 5-substituted-1,3,4-oxadiazole Mannich bases and bis-Mannich bases as ketol-acid reductoisomerase inhibitors

(2016) Yan Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Novel 1,3,4-oxadiazole/oxime hybrids: Synthesis, docking studies and investigation of anti-inflammatory, ulcerogenic liability and analgesic activities

(2016) Heba S. Abd-Ellah et al.   BIOORGANIC CHEMISTRY

Synthesis, characterization and antimicrobial activity of benzodioxane ring containing 1,3,4-oxadiazole derivatives

(2016) Habibullah Khalilullah et al.   Arabian Journal of Chemistry

Synthesis, characterization and pharmacological screening of novel benzimidazole derivatives

(2016) Mohammad Shaharyar et al.   Arabian Journal of Chemistry

Synthesis and biological activities of Bis alkyl 1,3,4-oxadiazole incorporated azo dye derivatives

(2016) A.H. Shridhar et al.   Arabian Journal of Chemistry

Synthesis and broad-spectrum antiproliferative activity of diarylamides and diarylureas possessing 1,3,4-oxadiazole derivatives

(2015) Mahmoud M. Gamal El-Din et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and in vitro antiproliferative activity of new 1,3,4-oxadiazole derivatives possessing sulfonamide moiety

(2015) Mahmoud M. Gamal El-Din et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, characterization, evaluation and molecular dynamics studies of 5, 6–diphenyl–1,2,4–triazin–3(2 H )–one derivatives bearing 5–substituted 1,3,4–oxadiazole as potential anti–inflammatory and analgesic agents

(2015) Anupam G. Banerjee et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

One-Pot Synthesis of 2,5-Diaryl 1,3,4-Oxadiazoles via Di-tert-butyl Peroxide Promoted N-Acylation of Aryl Tetrazoles with Aldehydes

(2015) Liang Wang et al.   JOURNAL OF ORGANIC CHEMISTRY

Direct Annulation of Hydrazides to 1,3,4-Oxadiazoles via Oxidative C(CO)–C(Methyl) Bond Cleavage of Methyl Ketones

(2015) Qinghe Gao et al.   ORGANIC LETTERS

Photocatalytic Oxidative Heterocyclization of Semicarbazones: An Efficient Approach for the Synthesis of 1,3,4-Oxadiazoles

(2015) Lal Yadav et al.   SYNLETT

Tandem Prins and Friedel–Crafts Cyclizations for the Stereo­selective Synthesis of trans-Fused Hexahydro-1H-benzo[g]isochromene Derivatives

(2015) B. Reddy et al.   SYNTHESIS-STUTTGART

Synthesis, characterization and anticancer studies of new steroidal oxadiazole, pyrrole and pyrazole derivatives

(2015) Shamsuzzaman et al.   Journal of Saudi Chemical Society

Zibotentan

(2015) N.D. James et al.   DRUGS OF THE FUTURE

Design, synthesis, and antibacterial activity against rice bacterial leaf blight and leaf streak of 2,5-substituted-1,3,4-oxadiazole/thiadiazole sulfone derivative

(2014) Pei Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of 2-Amino-1,3,4-oxadiazoles and 2-Amino-1,3,4-thiadiazoles via Sequential Condensation and I2-Mediated Oxidative C–O/C–S Bond Formation

(2014) Pengfei Niu et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis, antibacterial and anticancer evaluation of 5-substituted (1,3,4-oxadiazol-2-yl)quinoline

(2014) Salahuddin et al.   MEDICINAL CHEMISTRY RESEARCH

Pd-Catalyzed Oxidative Annulation of Hydrazides with Isocyanides: Synthesis of 2-Amino-1,3,4-oxadiazoles

(2014) Tao Fang et al.   ORGANIC LETTERS

A Facile and Expeditious One-Pot Synthesis of α-Keto-1,3,4-oxadiazoles

(2014) Dalip Kumar et al.   SYNLETT

Synthesis and Anticancer Activity ofN-Aryl-5-substituted-1,3,4-oxadiazol-2-amine Analogues

(2014) Mohamed Jawed Ahsan et al.   Biomed Research International

Synthesis, Characterization, andIn VitroAnticancer Evaluation of Novel 2,5-Disubstituted 1,3,4-Oxadiazole Analogue

(2014) Salahuddin et al.   Biomed Research International

Novel pyrazole integrated 1,3,4-oxadiazoles: Synthesis, characterization and antimicrobial evaluation

(2013) Srikantamurthy Ningaiah et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis, Insecticidal Activities, and SAR Studies of Novel Pyridylpyrazole Acid Derivatives Based on Amide Bridge Modification of Anthranilic Diamide Insecticides

(2013) Bao-Lei Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

I2-Mediated Oxidative C–O Bond Formation for the Synthesis of 1,3,4-Oxadiazoles from Aldehydes and Hydrazides

(2013) Wenquan Yu et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis and Evaluation of In Vivo Anticonvulsant Activity of 2,5- Disubstituted-1,3,4-Oxadiazole Derivatives

(2013) Kikkeri Harish et al.   Letters in Drug Design & Discovery

Synthesis, characterization and anticancer evaluation of 2-(naphthalen-1-ylmethyl/naphthalen-2-yloxymethyl)-1-[5-(substituted phenyl)-[1,3,4]oxadiazol-2-ylmethyl]-1H-benzimidazole

(2013) Salahuddin et al.   Arabian Journal of Chemistry

Novel limonene and citral based 2,5-disubstituted-1,3,4-oxadiazoles: A natural product coupled approach to semicarbazones for antiepileptic activity

(2012) Harish Rajak et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Regioselective Synthesis of 2-Amino-Substituted 1,3,4-Oxadiazole and 1,3,4-Thiadiazole Derivatives via Reagent-Based Cyclization of Thiosemicarbazide Intermediate

(2012) Seung-Ju Yang et al.   JOURNAL OF ORGANIC CHEMISTRY

1,3,4-Oxadiazole: A Biologically Active Scaffold

(2012) H. Khalilullah et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

A Novel Strategy for the Construction of Azole Heterocycles via an Oxidative Desulfurization Approach Using Iodobenzene and Oxone®

(2012) Vikas Telvekar et al.   SYNLETT

Synthesis and Antimicrobial Activity of New 2,5-Disubstituted 1,3,4-Oxadiazoles and 1,2,4-Triazoles and Their Sugar Derivatives

(2011) Wael A. El-Sayed et al.   CHINESE JOURNAL OF CHEMISTRY

Synthesis, antibacterial evaluation and QSAR studies of 7-[4-(5-aryl-1,3,4-oxadiazole-2-yl)piperazinyl] quinolone derivatives

(2011) Rajnish Kumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Cu(II) Catalyzed Imine C–H Functionalization Leading to Synthesis of 2,5-Substituted 1,3,4-Oxadiazoles‡

(2011) Srimanta Guin et al.   ORGANIC LETTERS

Synthesis and in vitro antibacterial activity of new oxoethylthio-1,3,4-oxadiazole derivatives

(2011) Jignesh P. Raval et al.   Journal of Saudi Chemical Society

Synthesis and antimicrobial screening of 1,3,4-oxadiazole and clubbed thiophene derivatives

(2011) N.C. Desai et al.   Journal of Saudi Chemical Society

Novel semicarbazones based 2,5-disubstituted-1,3,4-oxadiazoles: One more step towards establishing four binding site pharmacophoric model hypothesis for anticonvulsant activity

(2010) Harish Rajak et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Microwave assisted one pot synthesis of some novel 2,5-disubstituted 1,3,4-oxadiazoles as antifungal agents

(2010) Jaiprakash N. Sangshetti et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of substituted acridinyl pyrazoline derivatives and their evaluation for anti-inflammatory activity

(2010) Trilok Chandra et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis and biological evaluation of 1,3,4-oxadiazole derivatives

(2010) Keshari Kishore Jha et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, characterization and antimicrobial activity of some disubstituted 1,3,4-oxadiazoles carrying 2-(aryloxymethyl)phenyl moiety

(2010) Channamata Shankara Naveena et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and bioassay of aminosulfonyl-1,3,4-oxadiazoles and their interconversion to 1,3,4-thiadiazoles

(2010) V. Padmavathi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Derivatives of benzimidazole pharmacophore: Synthesis, anticonvulsant, antidiabetic and DNA cleavage studies

(2010) Ramya V. Shingalapur et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Vasorelaxant effect in rat aortic rings through calcium channel blockage: A preliminary in vitro assessment of a 1,3,4-oxadiazole derivative

(2009) Girish R. Bankar et al.   CHEMICO-BIOLOGICAL INTERACTIONS

A possible correlation between the correction of endothelial dysfunction and normalization of high blood pressure levels by 1,3,4-oxadiazole derivative, an L-type Ca2+ channel blocker in deoxycorticosterone acetate and NG-nitro-l-arginine hypertensive rats

(2009) Girish R. Bankar et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Emerging Treatments in Cystic Fibrosis

(2009) Andrew M. Jones et al.   DRUGS

Fenbufen based 3-[5-(substituted aryl)-1,3,4-oxadiazol-2-yl]-1-(biphenyl-4-yl)propan-1-ones as safer antiinflammatory and analgesic agents

(2009) Asif Husain et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and pharmacological evaluation of 1,3,4-oxadiazole bearing bis(heterocycle) derivatives as anti-inflammatory and analgesic agents

(2009) B. Jayashankar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, characterization and biological activity of some new 1,3,4-oxadiazole bearing 2-flouro-4-methoxy phenyl moiety

(2009) B. Chandrakantha et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors

(2009) Erik Serrao et al.   Retrovirology

Reaction between N-Isocyaniminotriphenylphosphorane, Aldehydes, and Carboxylic Acids: A One-Pot and Three-Component Synthesis of 2-Aryl-5-hydroxyalkyl-1,3,4-oxadiazoles

(2009) Mehdi Adib et al.   SYNLETT

1,3,4-Oxadiazole-3(2H)-carboxamide derivatives as potential novel class of monoamine oxidase (MAO) inhibitors: Synthesis, evaluation, and role of urea moiety

(2008) Shaoyong Ke et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection

(2008) Vincenzo Summa et al.   JOURNAL OF MEDICINAL CHEMISTRY