Article
Infectious Diseases
Taehyeong Lim, So-Young Ham, SangJin Nam, Myoungsun Kim, Ki Yong Lee, Hee-Deung Park, Youngjoo Byun
Summary: This article reviews recent studies on small molecules targeting the RhlI/RhlR system in P. aeruginosa, discussing their in vitro and in vivo biological activities. The article focuses on structure-activity relationship studies and the outlook for next-generation anti-biofilm agents.
Article
Biotechnology & Applied Microbiology
James Redfern, Janine Wallace, Alex van Belkum, Magali Jaillard, Elliot Whittard, Roobinidevi Ragupathy, Joanna Verran, Peter Kelly, Mark Charles Enright
Summary: Pseudomonas aeruginosa is a common environmental microorganism that can form biofilms on indwelling device surfaces, promoting adhesion and survival. Research identified accessory genes and core-genome SNPs associated with enhanced biofilm production at 22 degrees C, including a 165 kb genomic island with heavy metal resistance genes.
Article
Infectious Diseases
Tomasz Bogiel, Dagmara Depka, Mateusz Rzepka, Joanna Kwiecinska-Pirog, Eugenia Gospodarek-Komkowska
Summary: The study investigated the frequency and genotype distribution of 10 virulence factor genes in 107 non-duplicated carbapenem-resistant P. aeruginosa isolates. Variations were observed in the prevalence and distribution of virulence genes, especially in terms of their carbapenemase synthesis ability and the strain origin.
Article
Biology
Steffen Geisel, Eleonora Secchi, Jan Vermant
Summary: Biofilms are bacterial communities encased by a self-produced matrix, and the channel networks formed within the biofilm play a vital role in promoting the transport of nutrients and chemicals. This study focuses on the role of the biofilm matrix adhesion in channel formation, specifically in Pseudomonas aeruginosa biofilms grown under constant flow in microfluidic channels. The formation of wrinkles and folds is triggered by a mechanical buckling instability, resulting in hollow channels that facilitate bacterial movement.
Review
Biotechnology & Applied Microbiology
Anming Xu, Xiaoxiao Zhang, Tong Wang, Fengxue Xin, Luyan Z. Ma, Jie Zhou, Weiliang Dong, Min Jiang
Summary: Pseudomonas aeruginosa is known for its excellent ecological flexibility and can survive in diverse niches. The adaptive mutants RSCVs have been frequently isolated from chronic infections, sparking interest in investigating their formation, persistence, and pathogenesis. RSCVs are believed to play a significant role in biofilm formation and high adaptability.
BIOTECHNOLOGY ADVANCES
(2021)
Article
Chemistry, Physical
Jacobo Hernandez-Montelongo, Gianlucca G. Nicastro, Thays de O. Pereira, Mariana Zavarize, Marisa M. Beppu, Waldemar A. A. Macedo, Regina L. Baldini, Monica A. Cotta
Summary: Materials coated with nanofilms obtained by polyelectrolytes assembled layer-by-layer show promising antibacterial effects, with nanofilms of hyaluronan/chitosan (HA/CHI) exhibiting satisfactory effects against certain human pathogenic bacteria but less efficient against Pseudomonas aeruginosa. Understanding the interaction between P. aeruginosa and HA/CHI nanofilms involves evaluating the role of type IV pili (T4P) and lipopolysaccharide (LPS) structures in initial adhesion, with genetically modified strains revealing different adhesion behaviors. Although the HA/CHI nanofilm demonstrates antibacterial effects, the lack of LPS may partially protect bacteria from the nanofilm, affecting its efficiency over longer culture times.
SURFACES AND INTERFACES
(2021)
Article
Chemistry, Multidisciplinary
Xiaodie Yuan, Xia Zhao, Yuan Lin, Zhaohui Su
Summary: This study synthesized PDA nanoparticles of various sizes and introduced different surface groups to investigate their penetration and accumulation abilities in biofilms. The PDA nanoparticles of approximately 60 nm size showed higher penetration and accumulation abilities, and the positively charged amine groups were more effective in enhancing the interactions with the biofilm compared to carboxyl or methoxy groups. The PDA60 nanoparticles with amine surface groups also exhibited good photothermal properties.
Article
Infectious Diseases
Emilie Charpentier, Ludovic Doudet, Ingrid Allart-Simon, Marius Colin, Sophie C. Gangloff, Stephane Gerard, Fany Reffuveille
Summary: The combination of non-antimicrobial molecules with antibiotics can significantly reduce bacterial biofilm formation, potentially offering a solution to combat antibiotic resistance emergence.
Article
Biochemistry & Molecular Biology
Marta Guerini, Pietro Grisoli, Cristina Pane, Paola Perugini
Summary: This study aimed to develop microstructured lipid carriers (MLC) based on chitosan and containing N-acetylcysteine (NAC) to inhibit biofilm formation of Pseudomonas aeruginosa. The use of chitosan as a carrier allowed for the production of microstructured particles with narrow size range and high encapsulation efficiency. NAC-loaded MLC demonstrated increased antioxidant activity compared to free molecules and showed significant inhibition of biofilm growth by Pseudomonas aeruginosa.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Pharmacology & Pharmacy
Davoodbasha MubarakAli, Kannappan Arunachalam, Murugan Lakshmanan, Bazigha Badar, Jung-Wan Kim, Sang-Yul Lee
Summary: Biofilm-related nosocomial infections can cause various life-threatening infections. In this study, hydroxyapatite nanoparticles (HANPs) were synthesized using a co-precipitation method followed by microwave treatment, and their ability to inhibit the biofilm formation of Pseudomonas aeruginosa ATCC 10145 was investigated. The results showed that the synthesized HANPs effectively inhibited biofilm formation, suggesting their potential use in controlling biofilm-related infections caused by Pseudomonas aeruginosa.
Article
Immunology
Zuoji Ye, Liumei Ye, Dingbin Li, Shunsheng Lin, Wusheng Deng, Li Zhang, Jinhua Liang, Jinlong Li, Qingjun Wei, Ke Wang
Summary: In this study, the researchers found that Daphnetin (DAP) can effectively inhibit and eradicate biofilm formation of Pseudomonas aeruginosa. DAP also reduced bacterial motility and pyocyanin production. These findings suggest that DAP may serve as a natural anti-biofilm therapeutic agent.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Christian Schuetz, Duy-Khiet Ho, Mostafa Mohamed Hamed, Ahmed Saad Abdelsamie, Teresa Roehrig, Christian Herr, Andreas Martin Kany, Katharina Rox, Stefan Schmelz, Lorenz Siebenbuerger, Marius Wirth, Carsten Boerger, Samir Yahiaoui, Robert Bals, Andrea Scrima, Wulf Blankenfeldt, Justus Constantin Horstmann, Rebekka Christmann, Xabier Murgia, Marcus Koch, Aylin Berwanger, Brigitta Loretz, Anna Katharina Herta Hirsch, Rolf Wolfgang Hartmann, Claus-Michael Lehr, Martin Empting
Summary: A new generation of quorum sensing inhibitors (QSI) is reported to effectively inhibit the virulence of Pseudomonas aeruginosa and enhance antibiotic efficacy, potentially preventing the development of antimicrobial resistance. Additionally, a significant synergistic effect of QSI in combination with tobramycin against P. aeruginosa biofilms is demonstrated, showing promising implications for adjunctive pathoblocker-mediated therapy.
Article
Chemistry, Multidisciplinary
Pengyu Li, Jieyi Pan, Yating Dong, Yingying Sun, Yalong Wang, Kang Liao, Yili Chen, Xin Deng, Shihui Yu, Haiyan Hu
Summary: Chronic pulmonary infection caused by Pseudomonas aeruginosa is a serious public health problem with high mortality rates. In this study, infection-microenvironment responsive nanoparticles were developed to eradicate biofilms and inhibit virulence. These nanoparticles showed promising results in treating chronic pulmonary infections.
JOURNAL OF CONTROLLED RELEASE
(2024)
Article
Immunology
Qi Tan, Qing Ai, Yu He, Fang Li, Jialin Yu
Summary: The ability of P.aeruginosa biofilms to activate inflammasomes and increase inflammatory response contributes to chronic infection. This study found that P.aeruginosa biofilms significantly enhance the production of IL-1β and IL-18, possibly through the regulation of NLRP3 inflammasomes rather than NLRC4 inflammasomes.
MICROBIAL PATHOGENESIS
(2022)
Article
Immunology
Laia Fernandez-Barat, Nil Vazquez Burgos, Victoria Alcaraz, Leticia Bueno-Freire, Ruben Lopez-Aladid, Roberto Cabrera, Albert Gabarrus, Andrea Palomeque, Patricia Oscanoa, Adrian Ceccato, Ana Motos, Rosanel Amaro, Thierry Bernardi, Christian Provot, Alba Soler-Comas, Laura Munoz, Jordi Vila, Antoni Torres
Summary: The aim of this study was to validate and identify additional applications of the BioFilm Ring Test (BRT) for Pseudomonas aeruginosa (PA) isolates from patients with bronchiectasis (BE), and evaluate its relationship with antimicrobial stewardship. The results showed that a BPI value below 14.75 at 5 hours predicted the mucoid PA phenotype. In conclusion, the BRT has the potential to reveal biofilm features with clinical implications.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Article
Polymer Science
Neslihan Nohut Maslakci, Abdullah Bicer, Gunseli Turgut Cin, Aysegul Uygun Oksuz
JOURNAL OF APPLIED POLYMER SCIENCE
(2018)
Article
Chemistry, Medicinal
Sevda Turk, Sevgi Karakus, Abdulilah Ece, Seyhan Ulusoy, Gulgun Bosgelmez-Tinaz
LETTERS IN DRUG DESIGN & DISCOVERY
(2019)
Article
Polymer Science
Cigdem Dulgerbaki, Neslihan Nohut Maslakci, Ali Ihsan Komur, Aysegul Uygun Oksuz
EUROPEAN POLYMER JOURNAL
(2018)
Article
Polymer Science
Sibel Kaplan, Selcuk Aslan, Seyhan Ulusoy, Ayhan Oral
JOURNAL OF APPLIED POLYMER SCIENCE
(2020)
Article
Chemistry, Multidisciplinary
Gunseli Turgut Cin, Neslihan Nohut Maslakci, Abdullah Bicer, Gul Yakal, Aysegul Uygun Oksuz
Article
Nanoscience & Nanotechnology
Gulsah Ballica, Halime Cevikbas, Seyhan Ulusoy, Yeliz Yildirim
APPLIED NANOSCIENCE
(2020)
Article
Nanoscience & Nanotechnology
Gozde Yurdabak Karaca, Filiz Kuralay, Ozlem Bingol Ozakpinar, Emre Uygun, Umran Koc, Seyhan Ulusoy, Gulgun Bosgelmez Tinaz, Lutfi Oksuz, Aysegul Uygun Oksuz
Summary: The study focused on the preparation and characterization of catalytic gold/poly(3,4-ethylenedioxythiophene)/platinum micromotors for cancer biomarker miRNA-21 detection, and also explored their potential use in cancer treatment. Intracellular studies demonstrated the high selectivity of the micromotors for specific cancer cells, highlighting their potential in targeted cancer therapy.
APPLIED NANOSCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Neslihan Nohut Maslakci
Summary: The study evaluated pH-dependent drug release from PVP/PAN/Gr fibers using QCM, showing different drug release amounts at different pH levels, with higher release at pH 5.4.
Article
Biotechnology & Applied Microbiology
Seda Bikric, Belma Aslim, Ilknur Dincer, Zehranur Yuksekdag, Seyhan Ulusoy, Serkan Yavuz
Summary: This study aimed to reveal the potential of using exopolysaccharides obtained from Ligilactobacillus salivarius as a prebiotic that regulates chicken intestinal microbiota. The EPS showed anti-biofilm and anti-quorum sensing effects, promoted lactobacilli growth, and increased adhesion abilities in colorectal adenocarcinoma cell line. These characterized EPS may serve as an alternative to plant prebiotics such as inulin in poultry.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2022)
Article
Microbiology
Seyhan Ulusoy, Ramadan B Akalin, Halime cevikbas, Avni Berisha, Ayhan Oral, Gulgun Bosgelmez-Tinaz
Summary: The study shows that zeolites can disrupt the QS systems of Chromobacterium violaceum and Pseudomonas aeruginosa by adsorbing AHL signal molecules, reducing their production and virulence. This finding may provide new insights for the treatment of P. aeruginosa-related infections.
FUTURE MICROBIOLOGY
(2022)
Article
Materials Science, Multidisciplinary
Neslihan Nohut Maslakci, Esin Eren, Kadinsah Nur Kocer, Halime Cevikbas, Seyhan Ulusoy, Abdullah Bicer, Gunseli Turgut Cin, Aysegul Uygun Oksuz
Summary: The aim of this study is to fabricate bis-chalcone/poly(methyl methacrylate) (PMMA)/poly(ethylene oxide) (PEO) based fiber mats loaded with streptomycin sulfate (STM) for drug delivery and antibacterial applications. The study demonstrates the synergistic effect of bis-chalcone derivatives (BTC or BNC) on STM loading and antibacterial properties of the fibers. Characterization techniques including FTIR, SEM, and EDS were used to analyze the morphology, elemental composition, and molecular chain structures of the electrospun fibers. PMMA/PEO/BTC-STM60 fiber exhibited the longest drug release profile and showed effective inhibition against Bacillus cereus and Escherichia coli.
MATERIALS TODAY COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Hayfa Argui, Salih Can Suner, Cagdas Deniz Periz, Seyhan Ulusoy, Gulen Turker, Mossadok Ben-Attia, Fikret Buyukkaya, Ayhan Oral, Yalcin Coskun, Hechmi Said
Summary: This study successfully prepared poly (lactic acid) nanofibers containing cypress essential oil using electrospinning technology. The thermal stability of the nanofibers decreased with the increase of cypress essential oil content, while the flexibility increased. The nanofibers showed antibacterial activity against Escherichia coli and Staphylococcus aureus, with inhibition zone diameters larger than those in the presence of Kanamycin.
Article
Plant Sciences
Hayfa Argui, Oumayma Ben Youchret-Zalleza, Salih Can Suner, Cagdas Deniz Periz, Gulen Turker, Seyhan Ulusoy, Mossadok Ben-Attia, Fikret Buyukkaya, Ayhan Oral, Yalcin Coskun, Hechmi Said
Summary: The Cupressus sempervirens L. essential oil exhibited significant antioxidant and antibacterial activities, particularly against Staphylococcus aureus, Enterococcus faecalis, and Escherichia coli. It also showed contact toxic effect and repellent activity against Sitophilus granarius adults.
JOURNAL OF ESSENTIAL OIL BEARING PLANTS
(2021)
Article
Multidisciplinary Sciences
Cansel Dogan, Aysegul Uygun Oksuz, Neslihan Nohut Maslakci, Esin Eren, Emre Uygun, Lutfi Oksuz
ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING
(2019)
Article
Chemistry, Multidisciplinary
Neslihan Nohut Maslakci, Seyhan Ulusoy, Aysegul Uygun Oksuz
MOLECULAR CRYSTALS AND LIQUID CRYSTALS
(2018)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
